Synergistic effects of quercetin-loaded CoFe ₂ O ₄ @Liposomes regulate DNA damage and apoptosis in MCF-7 cancer cells: based on biophysical magnetic hyperthermia

Drug Development and Industrial Pharmacy, Год журнала: 2024, Номер 50(6), С. 561 - 575

Опубликована: Июнь 2, 2024

Breast cancer (BC) is the most common malignancy in women globally. Significant progress has been made developing structural nanoparticles (NPs) and formulations for targeted smart drug delivery (SDD) of pharmaceuticals, improving precision tumor cell targeting therapy.

Язык: Английский

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A Compendium of Magnetic Nanoparticle Essentials: A Comprehensive Guide for Beginners and Experts

Pharmaceutics, Год журнала: 2025, Номер 17(1), С. 137 - 137

Опубликована: Янв. 20, 2025

Magnetic nanoparticles (MNPs) are advanced materials that combine the unique properties of magnetic and nanoscale dimensions, enabling a wide range applications in biomedicine, environmental science, information technology. This review provides comprehensive yet accessible introduction to fundamental principles, characterization techniques, diverse MNPs, with focus on their properties, such as superparamagnetism, single-domain behavior, surface effects. It also delves into classification critical role parameters like anisotropy blocking temperature. Emphasis is placed routine methods, including X-ray diffraction, electron microscopy, magnetometry, well concepts hyperthermia self-regulated heating. Designed for newcomers experts alike, this serves both an educational guide quick-reference resource, ensuring clarity while maintaining scientific rigor.

Язык: Английский

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Elastic Liposomes Containing Calcium/Magnesium Ferrite Nanoparticles Coupled with Gold Nanorods for Application in Photothermal Therapy

Nanomaterials, Год журнала: 2024, Номер 14(8), С. 679 - 679

Опубликована: Апрель 15, 2024

This work reports on the design, development, and characterization of novel magneto-plasmonic elastic liposomes (MPELs) DPPC:SP80 (85:15) containing Mg0.75Ca0.25Fe2O4 nanoparticles coupled with gold nanorods, for topical application photothermal therapy (PTT). Both magnetic plasmonic components were characterized regarding their structural, morphological, properties. The display a cubic shape size (major axis) 37 ± 3 nm, while longitudinal transverse sizes nanorods are 46 7 nm 12 1.6 respectively. A new methodology was employed to couple nanostructures, using cysteine as bridge. potential photothermia evaluated nanoparticles, magnetic/plasmonic which demonstrated maximum temperature variation 28.9 °C, 33.6 °C 37.2 respectively, during 30 min NIR-laser irradiation 1 mg/mL dispersions. Using fluorescence anisotropy studies, phase transition (Tm) 35 estimated MPELs, ensures an enhanced fluidity crucial effective crossing skin layers. this nanostructure corresponds specific absorption rate (SAR) 616.9 W/g increase 33.5 °C. These findings point development thermoelastic nanocarriers suitable features act hyperthermia agents.

Язык: Английский

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Green synthesis of Cubic Spinel ferrites and their Potential biomedical applications

Ceramics International, Год журнала: 2024, Номер unknown

Опубликована: Окт. 1, 2024

Язык: Английский

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