Potential Molecular Mechanisms of Alcohol Use Disorder with Non-Coding RNAs and Gut Microbiota for the Development of Superior Therapeutic Application

Genes, Год журнала: 2024, Номер 15(4), С. 431 - 431

Опубликована: Март 29, 2024

Many investigations have evaluated the expression of noncoding RNAs (ncRNAs) as well their related molecular functions and biological machineries in individuals with alcohol dependence. Alcohol dependence may be one most prevailing psychological disorders globally, its pathogenesis is intricate inadequately comprehended. There substantial evidence indicating significant links between multiple genetic factors development In particular, critical roles ncRNAs been emphasized pathology mental illnesses, probably including comprehension action modification, furthermore, they emerged therapeutic targets for a variety psychiatric It worth mentioning that dysregulated has regularly detected An in-depth knowledge m6A modification valuable novel treatment against general, more profound understanding practical might make important contributions to precise diagnosis and/or actual management Here, this review, we mostly focused on up-to-date regarding alterations modifications Then, present prospects future research applications concept engram system.

Язык: Английский

Gut Microbiota and Non-coding RNAs Might Be Involved in the Pathogenesis of Alcohol Dependence

Опубликована: Фев. 27, 2024

A great deal of studies have assessed the expression noncoding RNAs (ncRNAs) as well their relevant molecular functions and biological mechanisms in individuals alcohol dependence. Alcohol dependence is one most prevalent neuropsychological disorders worldwide, its pathogenesis intricate inadequately understood. There considerable evidence demonstrating substantial links between multiple genetic factors development Critical roles ncRNAs been emphasized pathophysiology mental diseases including In comprehension action modification, they emerged therapeutic targets for a variety psychiatric illness Worth mentioning, dysregulated has regularly detected An in-depth knowledge m6A modification may be valuable novel treatment against general, deeper functional make significant contributions to precise diagnosis and/or actual Here this review, we mostly focused on up-to-date regarding alterations modifications dependence, then, presented prospects future research application with concept engram-system.

Язык: Английский

Scientific investigation of non-coding RNAs in mitochondrial epigenetic and aging disorders: Current nanoengineered approaches for their therapeutic improvement

Mitochondrion, Год журнала: 2024, Номер 80, С. 101979 - 101979

Опубликована: Ноя. 5, 2024

Язык: Английский