Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(17), С. 9588 - 9588

Опубликована: Авг. 24, 2022

Food components in our diet provide not only necessary nutrients to body but also substrates for the mutualistic microbial flora gastrointestinal tract, termed gut microbiome. Undigested food are metabolized a diverse array of metabolites. Thus, what we eat shapes structure, composition, and function microbiome, which interacts with epithelium mucosal immune system maintains intestinal homeostasis healthy state. Alterations microbiome implicated many diseases, such as inflammatory bowel disease (IBD). There is growing interest nutritional therapy target IBD. Investigations into dietary effects on composition changes flourished recent years, few focused physiology. This review summarizes current knowledge regarding impacts major their metabolites health consequences, specifically within GI tract. Additionally, influence microbiome-host interaction IBD discussed. Understanding host will be useful developing strategies maintain restore

Язык: Английский

---

Faecalibacterium: a bacterial genus with promising human health applications

FEMS Microbiology Reviews, Год журнала: 2023, Номер 47(4)

Опубликована: Июль 1, 2023

Abstract In humans, many diseases are associated with alterations in gut microbiota, namely increases or decreases the abundance of specific bacterial groups. One example is genus Faecalibacterium. Numerous studies have underscored that low levels Faecalibacterium correlated inflammatory conditions, bowel disease (IBD) forefront. Its representation also diminished case several diseases, including colorectal cancer (CRC), dermatitis, and depression. Additionally, relative presence this considered to reflect, at least part, intestinal health status because frequently present reduced individuals gastrointestinal disorders. review, we first thoroughly describe updates taxonomy Faecalibacterium, which has transformed a single-species taxon multispecies over last decade. We then explore links discovered between various since IBD-focused were published. Next, examine current available strategies for modulating gut. Finally, summarize mechanisms underlying beneficial effects been attributed genus. Together, epidemiological experimental data strongly support use as next-generation probiotic (NGP) live biotherapeutic product (LBP).

Язык: Английский

---

The Role of Diet and Nutritional Interventions for the Infant Gut Microbiome

Nutrients, Год журнала: 2024, Номер 16(3), С. 400 - 400

Опубликована: Янв. 30, 2024

The infant gut microbiome plays a key role in the healthy development of human organism and appears to be influenced by dietary practices through multiple pathways. First, maternal diet during pregnancy nutrition significantly influence microbiota. Moreover, breastfeeding fosters proliferation beneficial bacteria, while formula feeding increases microbial diversity. timing introducing solid foods also influences microbiota composition. In preterm infants is factors, including time since birth intake breast milk, interventions such as probiotics prebiotics supplementation show promising results reducing morbidity mortality this population. These findings underscore need for future research understand long-term health impacts these further strategies enrich formula-fed infants.

Язык: Английский

---

Critical Review of the Cross-Links Between Dietary Components, the Gut Microbiome, and Depression

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(2), С. 614 - 614

Опубликована: Янв. 13, 2025

The complex relationship between diet, the gut microbiota, and mental health, particularly depression, has become a focal point of contemporary research. This critical review examines how specific dietary components, such as fiber, proteins, fats, vitamins, minerals, bioactive compounds, shape microbiome influence microbial metabolism in order to regulate depressive outcomes. These dietary-induced changes microbiota can modulate production metabolites, which play vital roles gut–brain communication. axis facilitates this communication through neural, immune, endocrine pathways. Alterations metabolites central nervous system (CNS) functions by impacting neuroplasticity, inflammatory responses, neurotransmitter levels—all are linked onset course depression. highlights recent findings linking components with beneficial composition reduced symptoms. We also explore challenges individual variability responses interventions long-term sustainability these strategies. underscores necessity for further longitudinal mechanistic studies elucidate precise mechanisms diet interactions be leveraged mitigate paving way personalized nutritional therapies.

Язык: Английский

---

An Integrated Approach to Skeletal Muscle Health in Aging

Nutrients, Год журнала: 2023, Номер 15(8), С. 1802 - 1802

Опубликована: Апрель 7, 2023

A decline in muscle mass and function represents one of the most problematic changes associated with aging, has dramatic effects on autonomy quality life. Several factors contribute to inexorable process sarcopenia, such as mitochondrial autophagy dysfunction, lack regeneration capacity satellite cells. The physiologic motoneuron functionality aging is exacerbated by sedentary lifestyle that accompanies elderly people. Regular physical activity beneficial people, but need well-designed carefully administered training programs improve and, consequently, both functional ability Aging also causes alteration gut microbiota composition some advances research have elucidated interventions via microbiota–muscle axis potential ameliorate sarcopenic phenotype. mechanisms are involved vitamin D atrophy protection, demonstrated decreased muscular related deficiency. Malnutrition, chronic inflammation, deficiencies, an imbalance muscle–gut just a few can lead sarcopenia. Supplementing diet antioxidants, polyunsaturated fatty acids, vitamins, probiotics, prebiotics, proteins, kefir, short-chain acids could be nutritional therapies against Finally, personalized integrated strategy counteract sarcopenia maintain health skeletal muscles suggested this review.

Язык: Английский

---

The Impact of Food Additives on the Abundance and Composition of Gut Microbiota

Molecules, Год журнала: 2023, Номер 28(2), С. 631 - 631

Опубликована: Янв. 7, 2023

The gut microbiota has been confirmed as an important part in human health, and is even take ‘organ’. interaction between the host intestinal environment plays a key role digestion, metabolism, immunity, inflammation, diseases. dietary component major factor that affects composition function of microbiota. Food additives have widely used to improve color, taste, aroma, texture, nutritional quality processed food. increasing variety quantity food diets lead increased frequency dose exposure, especially artificial additives, which become concern consumers. There are studies focusing on impact microbiota, long-term exposure could induce changes microbes, related health disease. Therefore, aim this review summarize additives.

Язык: Английский

---

The ‘Whey’ to good health: Whey protein and its beneficial effect on metabolism, gut microbiota and mental health

Trends in Food Science & Technology, Год журнала: 2023, Номер 133, С. 1 - 14

Опубликована: Янв. 13, 2023

Язык: Английский

---

Gastrointestinal digestion of food proteins: Anticancer, antihypertensive, anti-obesity, and immunomodulatory mechanisms of the derived peptides

Food Research International, Год журнала: 2024, Номер 189, С. 114573 - 114573

Опубликована: Май 28, 2024

Язык: Английский

---

Effect of Bioactive Peptides on Gut Microbiota and Their Relations to Human Health

Foods, Год журнала: 2024, Номер 13(12), С. 1853 - 1853

Опубликована: Июнь 13, 2024

Bioactive peptides derived from both exogenous and endogenous origins have been studied extensively to use their beneficial effects in humans animals. exhibit bodily functions contribute a healthy gastrointestinal system by influencing barrier functions, immune responses, gut microbiota. Gut microbiota is diverse microbial community that significantly influences the overall well-being homeostasis of body. Factors such as diet, age, lifestyle, medication, environmental circumstances can affect composition diversity The disturbances or imbalances associated with various health problems. interplays between bioactive are not fully understood, but hold promise modulators promote health. Almost all research on human health, including development therapeutics nutritional interventions, uses cell culture, even though direct biofunctional activities only occur when absorbed intestine into blood system. This review focuses current understanding impact mechanisms novelty this lies its comprehensive analysis multifaceted interactions microbiota, integrating knowledge disciplines microbiology nutrition. By elucidating underlying identifying gaps, offers an outlook potential promoting shaping future therapeutic interventions.

Язык: Английский

---

Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes

Nutrients, Год журнала: 2024, Номер 16(2), С. 269 - 269

Опубликована: Янв. 16, 2024

Nutrition is one of the most influential environmental factors in both taxonomical shifts gut microbiota as well development type 2 diabetes mellitus (T2DM). Emerging evidence has shown that effects nutrition on these parameters not mutually exclusive and changes related metabolites such short-chain fatty acids (SCFAs) branched-chain amino (BCAAs) may influence systemic inflammation signaling pathways contribute to pathophysiological processes associated with T2DM. With this background, our review highlights macronutrients, carbohydrates, proteins, lipids, micronutrients, vitamins, minerals, T2DM, specifically through their alterations they produce. Additionally, we describe influences common food groups, which incorporate varying combinations macronutrients metabolic context mellitus. Overall, first line modifiable therapies management T2DM a better understanding mechanisms by its pathophysiology provides opportunities for optimizing dietary interventions.

Язык: Английский

---