Relationship between Atherogenic Dyslipidaemia and Lipid Triad and Scales That Assess Insulin Resistance

Nutrients, Год журнала: 2023, Номер 15(9), С. 2105 - 2105

Опубликована: Апрель 27, 2023

Background: Atherogenic dyslipidaemia (AD) and lipid triad (LT) are characterised by high triglyceride levels together with low HDL normal or LDL cholesterol favoured a persistent state of insulin resistance (IR), which increases the release free fatty acids from abdominal adipose tissue. This alteration in profile favours accelerated development atherosclerosis, is most important cause morbidity mortality all countries developed developing world. One elements that plays major role genesis AD IR. The aim this study was to determine relationship between variables assess atherogenic risk (AD LT) scales presenting resistance. Methods: A descriptive cross-sectional 418,343 workers conducted evaluate triad; three (Triglycerides/HDL, TyG index, METS-IR) established. usefulness IR for predicting LT calculated applying ROC curves, obtaining area under curve (AUC) cut-off points their sensitivity, specificity, Youden index. Multivariate analysis performed binary logistic regression. Results: prevalence high-risk values much higher people compared those without. curves present us an AUC two dyslipidaemias studied figures ranging 0.856 0.991, implies results good/very good. Conclusions: assessed revealed, mean triad. make it possible adequately classify presence LT. highest presented triglycerides/HDL scale, result close 1. METS-IR recommended formula estimate

Язык: Английский

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The impact of the COVID-19 pandemic and associated disruptions in health-care provision on clinical outcomes in people with diabetes: a systematic review

The Lancet Diabetes & Endocrinology, Год журнала: 2024, Номер 12(2), С. 132 - 148

Опубликована: Янв. 23, 2024

Язык: Английский

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How to cope with emerging viral diseases: lessons from South Korea's strategy for COVID-19, and collateral damage to cardiometabolic health

The Lancet Regional Health - Western Pacific, Год журнала: 2022, Номер 30, С. 100581 - 100581

Опубликована: Сен. 5, 2022

South Korea is a unique country in many aspects terms of its strategy against the COVID-19 pandemic. From February 2020, Korean government adopted active epidemiological investigations, strict isolation affected patients, and extensive public lockdowns, which were helpful controlling spread until end 2021. This stable situation has changed dramatically since Omicron variant-reportedly less severe but more infective than original strain-became dominant from January 2022. mid-February to mid-April 2022, daily cases increased steeply, reaching > 600,000 cases/day: highest incidence rate world at that time. Despite this rapid increase, eased preventive strategies progressively, based on belief efficacy >80% vaccine coverage population. Now, June improving. The mortality 0·13%: lowest among 30 countries with case counts. High (87·7%), efficient healthcare system, co-operation between private sectors central seem have contributed this. However, it should also be noted pandemic measures had negative influence cardiometabolic profiles country. Considering likelihood another novel variant SARS-CoV-2 or new infectious disease emerging future, understanding flexibly by could beneficial for countries.

Язык: Английский

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Sociocultural Influences Contribute to Overeating and Unhealthy Eating: Creating and Maintaining an Obesogenic Social Environment in Indigenous Communities in Urban Fiji

Nutrients, Год журнала: 2022, Номер 14(14), С. 2803 - 2803

Опубликована: Июль 8, 2022

Pacific Island countries (PICs), such as Fiji, lead the world statistics in obesity and deaths caused by non-communicable diseases. The impacts of overburden healthcare system social services have major on Fijian economy. This study is first its kind to undertake an in-depth exploration determinants epidemic PICs exploring sociocultural influences situations that impact nutrient transitions, overconsumption, unhealthy eating urban indigenous community. In-depth qualitative interviews were conducted with 15 women from largest center Fiji who self-identified gatekeepers family meal planning, preparing, shopping for groceries, fruits, vegetables. identified several cultural norms expectations both individuals providing food consuming create maintain obesogenic environment. Moreover, participants also shared a misplaced value meat, energy-dense foods, junk food, fast foods further contribute overeating within this These novel findings highlight importance considering may be used assist decision-makers developing contextualized prevention strategies health messaging target

Язык: Английский

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Influence of Sociodemographic Variables and Healthy Habits on the Values of Insulin Resistance Indicators in 386,924 Spanish Workers

Nutrients, Год журнала: 2023, Номер 15(24), С. 5122 - 5122

Опубликована: Дек. 16, 2023

Insulin resistance (IR) is an alteration of the action insulin in cells, which do not respond adequately to this action, leading increase blood glucose levels. IR produces a very diverse clinical picture and increases cardiometabolic risk population that suffers from it. Among factors influence are genetics, unhealthy lifestyle habits, overweight, obesity. The objective work was determine how different sociodemographic variables healthy habits values scales assess presenting group Spanish workers. An observational, cross-sectional, descriptive study carried out 386,924 workers regions. Different were studied (age, social class, educational level, smoking, Mediterranean diet, physical exercise) along with their association four evaluate (TyG index, TyG-BMI, METS-IR, TG/HDL-c). To analyse quantitative variables, Student's t test used, while Chi-squared used for qualitative variables. A multinomial logistic regression analysis performed, calculating odds ratio its 95% confidence intervals. accepted level statistical significance set at p < 0.05. In multivariate analysis, all except increased high on scales, especially sedentary low adherence diet. Our results demonstrate between practice regular exercise reduction IR; strong role diet as protective factor aging IR, has also been suggested other studies; and, finally, relationship socioeconomic IR.

Язык: Английский

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Use of lipid-lowering drugs in restricted health access settings: Results from the Trends in Drug Utilization During COVID-19 Pandemic in Turkey (PANDUTI-TR) study

Vascular Pharmacology, Год журнала: 2024, Номер 156, С. 107382 - 107382

Опубликована: Май 28, 2024

Язык: Английский

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The onset and the development of cardiometabolic aging: an insight into the underlying mechanisms

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Сен. 26, 2024

Metabolic compromise is crucial in aggravating age-associated chronic inflammation, oxidative stress, mitochondrial damage, increased LDL and triglycerides, elevated blood pressure. Excessive adiposity, hyperglycemia, insulin resistance due to aging are associated with levels of damaging free radicals, inducing a proinflammatory state hampering immune cell activity, leading malfunctioning cardiometabolic condition. The load redox imbalance contributing factors for morbidities via vascular remodelling endothelial damage. Recent evidence has claimed the importance gut microbiota maintaining regular metabolic which declines chronological comorbidities. Genetic mutations, polymorphic changes, environmental strongly correlate vulnerability aberrant changes by affecting key physiological pathways. Numerous studies have reported robust link between biological dysfunction. This review outlines scientific exploring potential mechanisms behind onset development cardiovascular issues, particularly exacerbated aging.

Язык: Английский

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Consistent service use before the COVID-19 pandemic predicted the continuity of face-to-face appointments during the lockdown among type 2 diabetes patients

Primary care diabetes, Год журнала: 2024, Номер 18(2), С. 230 - 237

Опубликована: Янв. 6, 2024

IntroductionThe COVID-19 pandemic affected diabetes care among type 2 (T2D) patients. However, it is not known whether the observed changes in concern all T2D patients equally. We examined health service usage and treatment outcomes according to pre-pandemic follow-up activity.MethodsWe analysed electronic records of 11 083 North Karelia, Finland (March 2017–March 2021), categorizing them by T2D-related in-person contact frequency. focused on HbA1c LDL measurement activity targets as indicators.ResultsOverall, recording rates for decreased during pandemic. They most but stayed at highest level with consistent face-to-face use, characterised proportion comorbidities elevated HbA1c. Their were negatively affected. In contrast, activities increased those no contact.ConclusionThose use greater needs more likely seek despite lockdown, negative effect was seen.

Язык: Английский

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Changes in Social Distancing within Post-Pandemic Architecture in the Context of Security Design: A Systematic Literature Search and Review

Civil Engineering and Architecture, Год журнала: 2024, Номер 12(3), С. 1690 - 1707

Опубликована: Апрель 9, 2024

Changes of social distancing in post-pandemic architecture the context security design" refers to changes spatial and protocols a building for preventing future pandemics design.In 2019, rapid spread COVID-19 has caused architecture, especially distancing.The built environment needs different strategies help prevent disease future.This study will review discuss within design.A systematic literature search defines previous research systematically, relates concepts, critically reanalyses data.The first step is systematically clear selection, second coding, third synthesis.The selection considered 109 papers (of which 39 were reviewed).The findings are five revealed using prevention strategies: standards integrating healthy environment; relationships interactions users' pattern activity; design related nature; (proxemics); place attachment.Each strategy demonstrates connection between security-pandemic variables environments that can spread.These support defining understanding need holistic analysis architecture.

Язык: Английский

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Assessment of nutritional status, anthropometry and sleep patterns of the obese patients during pre and post COVID-19 illness

Human Nutrition & Metabolism, Год журнала: 2024, Номер 36, С. 200265 - 200265

Опубликована: Апрель 17, 2024

Until COVID-19, obesity was the main pandemic of 21 century. To date, there have been 767984989 confirmed cases, and 6943390 include death cases COVID-19 (WHO). find prevalence Obesity among adults, to adjudge attitude behavior selected subjects towards eating healthy weight loss during pre- post-COVID-19. Subject selection done through non-probability judgemental sampling. Initially, 70 young adults between 18 - 39 years age were from different localities Delhi (NCR). The study conducted based on a questionnaire developed for survey. Based inclusion criteria only 50 further study. constructed into three phases arrangement elaborated as under. Phase 1 includes field study, clinical examination, biochemical analysis, phase II division experimental control groups, whereas III pre& post-COVID nutritional status, anthropometric assessment, beverage consumption, sleep patterns also assessed. nutrition intervention in E3 (balanced diet + nutrient supplement) showed significant difference with group followed by E2 (nutrient E1 diet). Our findings that Calorie, protein, fat, carbohydrates, sodium, potassium intake significantly decreased (P= <0.001) post-intervention, whereas, fiber, vitamin A, C, iron <0.001), calcium (p=0.006), increased post-intervention. changes parameters such waist-to-hip ratio (WHR), body mass index (BMI), fat% pre-COVID-19 higher both men women, but after following dietary recommendation physical activity found reduction WHR, BMI, women. p-value subjective quality, latency, habitual efficiency, disturbances, daytime dysfunction appears be less than 0.05 which shows it is significant. daily consumption various beverages listed above comparison pre-post intervention, kada 0.001 hence seems people no comorbidity 0.05, indicating majority participants (12%) diabetes took comparatively longer suffering other comorbidities Hypertension (7%), Hyperthyroidism (4%), Hypothyroidism, polycystic ovarian disease (PCOD) (3% each) respectively. In present we provided survey data about key aspects management (pre-and-post), current knowledge.

Язык: Английский

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