International Journal of Mental Health and Addiction,
Год журнала:
2023,
Номер
unknown
Опубликована: Март 21, 2023
Abstract
Background
Although
evidence
suggests
that
ultra-processed
food
(UPF)
consumption
may
trigger
addictive
behaviors,
the
association
between
UPF
intake
and
psychoactive
substances
remains
unclear
among
adolescents,
a
group
especially
vulnerable
to
addiction
its
potentially
harmful
effects
on
health.
Objective
To
analyze
of
alcohol,
tobacco,
illicit
drugs
in
adolescent
students.
Method
This
cross-sectional
study
analyzed
data
from
National
School-Based
Health
Survey
(PeNSE
2019),
which
collected
information
representative
population-based
sample
students
aged
13–17
years
Brazil.
was
self-reported
24-h
recall.
Lifetime
use
last
month
were
also
reported.
Multinomial
logistic
regression
models
estimated
relative
risk
ratios
(RRR)
(95%
confidence
intervals
–
CI)
because
outcome
variables
comprised
four
categories
representing
varying
frequencies
substances.
Results
The
mean
±
standard
error
number
different
consumed
95,074
adolescents
included
(52.3%
girls)
4.37
0.02.
results
adjusted
revealed
that,
compared
those
who
reported
low
(1
st
tertile),
more
(3
rd
tertile)
likely
report
frequent
(≥
3
days
month)
drinking
alcoholic
beverages
(RRR
=
2.19;
95%
CI:
1.87,
2.56),
2.22;
2.85)
occasional
(one
or
two
smoking
1.30;
1.05,
1.60).
Conclusions
associated
with
drug
national
Brazilian
adolescents.
Frontiers in Immunology,
Год журнала:
2024,
Номер
15
Опубликована: Март 11, 2024
Objective
To
explore
the
influence
of
serum
metabolites
on
risk
psoriasis.
Methods
In
initial
stage,
we
applied
Mendelian
randomization
to
evaluate
association
between
1,400
and
Causal
effects
were
primarily
assessed
through
Inverse-Variance
Weighted
method
Wald
Ratio’s
odds
ratios,
95%
confidence
intervals.
False
Discovery
Rate
was
used
for
multiple
comparison
corrections.
Sensitivity
analyses
conducted
using
Cochran’s
Q
Test,
MR-PRESSO.
MR-Steiger
Test
employed
check
reverse
causality.
validation
sought
other
sources
psoriasis
GWAS
data
verify
results
meta-analysis
combine
effect
sizes
obtain
robust
causal
relationships.
addition,
also
metabolic
pathway
enrichment
analysis
known
that
have
a
relationship
with
in
both
stages.
Results
identified
112
causally
associated
psoriasis,
including
32
metabolite
ratios
80
(69
11
unknown).
24
(16
known,
1
unknown,
7
ratios)
confirmed
onset.
Meta-analysis
showed
overall
combined
consistent
main
direction
Of
16
metabolites,
most
attributed
lipid
metabolism,
5
as
factors
8
protective
Peptidic
Gamma-glutamylvaline
levels
had
negative
while
exogenous
Catechol
sulfate
amino
acid
3-methylglutaconate
positive
disease
The
two
stages
are
mainly
enriched
following
pathways:
Glutathione
Alpha
Linolenic
Acid
Linoleic
Metabolism,
Biosynthesis
unsaturated
fatty
acids,
Arachidonic
Glycerophospholipid
metabolism.
Conclusion
Circulating
may
potential
risk,
targeting
specific
benefit
diagnosis,
assessment,
treatment.
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Апрель 11, 2024
Background
Ultra-processed
foods
(UPFs)
have
been
associated
with
a
higher
intake
of
added
sugars,
sodium,
and
unhealthy
fats;
however,
the
relationship
between
UPFs
quality
life
(QoL)
is
not
well
understood.
Methods
The
present
cross-sectional
study
included
193
Iranian
women
aged
18–48
years
body
mass
index
(BMI)
≥25
kg/m
2
.
were
identified
using
NOVA
classification.
QoL
was
evaluated
SF-36
questionnaire.
Anthropometric
measurements
composition
assessed
an
appropriate
method.
Results
mean
BMI
fat-free
(FFM)
subjects
30.90
46.69
kg,
respectively.
At
first,
significant
difference
observed
in
height
across
tertiles
UPF
consumption.
score
total
scale
66.90.
Women
who
tertile
3
had
23.59
units
lower
limitation
physical
capabilities
activity
(score
role-physical)
(
β
=
−23.59,
95%
CI:
−37.77–9.40,
p
0.001).
Among
those
highest
adherence
to
intake,
there
8.76
unit
reduction
addressing
feelings
energy
fatigue
(vitality
domain)
model
−8.76,
−16.42–1.11,
0.02).
Finally,
15.78
mental
health
scale,
specifically
states
anxiety
depression,
among
participants
third
−15.78,
−24.11–7.45,
<
Conclusion
Increased
consumption
women.
Further
studies
are
needed
confirm
these
findings
develop
effective
strategies
promote
healthy
food
choices.
Nutrients,
Год журнала:
2024,
Номер
16(12), С. 1902 - 1902
Опубликована: Июнь 17, 2024
Depression
is
a
major
global
health
concern
expected
to
worsen
by
2030.
In
2019,
28
million
individuals
were
affected
depressive
disorders.
Dietary
and
supplemental
vitamins
show
overall
favorable
preventative
therapeutic
effects
on
depression.
B
are
crucial
for
neurological
function
mood
regulation.
Deficiencies
in
these
linked
Studies
individual
promise
improving
symptoms,
particularly
thiamin,
riboflavin,
niacin,
folate.
Vitamin
C
deficiency
may
heighten
but
its
exact
role
not
fully
understood.
Seasonal
Affective
Disorder
(SAD)
associated
with
insufficient
sunlight
exposure
vitamin
D
deficiency.
supplementation
SAD
shows
inconsistent
results
due
methodological
variations.
Further
investigation
needed
understand
the
mechanisms
of
depression
treatment.
Moreover,
more
research
light
therapy’s
efficacy
underlying
involving
photoreceptors,
enzymes,
immune
markers
needed.
Although
dietary
depression,
dietitians
treating
psychiatric
disorders
face
challenges
diverse
study
designs,
making
direct
comparisons
difficult.
Therefore,
this
article
reviews
current
literature
assess
prevention
treatment
This
review
found
that,
although
evidence
supports
preventing
further
clarify
their
action
determine
most
effective
intervention
strategies.
Food & Function,
Год журнала:
2023,
Номер
14(16), С. 7631 - 7641
Опубликована: Янв. 1, 2023
Background:
Global
ultra-processed
food
(UPF)
consumption
has
risen
rapidly.
The
development
and
prognosis
of
depression
anxiety
remain
unclarified.
Herein,
we
aimed
to
examine
the
association
between
UPF
incidence
progression
trajectory
anxiety.
Methods:
In
our
study,
participants
were
recruited
2006
2010.
was
expressed
as
servings,
energy
ratio,
weight
ratio.
relationships
or
assessed
using
Cox
proportional
hazards
model.
Multi-state
models
used
explore
risks
all
transitions
from
a
healthy
state
then
all-cause
mortality.
Results:
Among
183
474
participants,
5453
diagnosed
with
6763
during
follow-up
13.1
years.
in
highest
quartile
(Q4)
ratio
had
an
increased
risk
compared
those
lowest
(Q1),
hazard
ratios
(HRs)
95%
confidence
intervals
[CIs]
1.22
(1.13-1.31),
1.13
(1.05-1.22),
1.26
(1.17-1.36),
respectively.
Similarly,
Q4
higher
anxiety,
HRs
(95%
CIs)
(1.06-1.21),
(1.05-1.21),
1.11
(1.04-1.19),
Q1.
study
also
found
significant
mortality,
which
disappeared
for
Conclusions:
Our
findings
revealed
that
is
associated
International Journal of Mental Health and Addiction,
Год журнала:
2023,
Номер
unknown
Опубликована: Март 21, 2023
Abstract
Background
Although
evidence
suggests
that
ultra-processed
food
(UPF)
consumption
may
trigger
addictive
behaviors,
the
association
between
UPF
intake
and
psychoactive
substances
remains
unclear
among
adolescents,
a
group
especially
vulnerable
to
addiction
its
potentially
harmful
effects
on
health.
Objective
To
analyze
of
alcohol,
tobacco,
illicit
drugs
in
adolescent
students.
Method
This
cross-sectional
study
analyzed
data
from
National
School-Based
Health
Survey
(PeNSE
2019),
which
collected
information
representative
population-based
sample
students
aged
13–17
years
Brazil.
was
self-reported
24-h
recall.
Lifetime
use
last
month
were
also
reported.
Multinomial
logistic
regression
models
estimated
relative
risk
ratios
(RRR)
(95%
confidence
intervals
–
CI)
because
outcome
variables
comprised
four
categories
representing
varying
frequencies
substances.
Results
The
mean
±
standard
error
number
different
consumed
95,074
adolescents
included
(52.3%
girls)
4.37
0.02.
results
adjusted
revealed
that,
compared
those
who
reported
low
(1
st
tertile),
more
(3
rd
tertile)
likely
report
frequent
(≥
3
days
month)
drinking
alcoholic
beverages
(RRR
=
2.19;
95%
CI:
1.87,
2.56),
2.22;
2.85)
occasional
(one
or
two
smoking
1.30;
1.05,
1.60).
Conclusions
associated
with
drug
national
Brazilian
adolescents.
