Evaluating Phthalates and Bisphenol in Foods: Risks for Precocious Puberty and Early-Onset Obesity

Nutrients, Год журнала: 2024, Номер 16(16), С. 2732 - 2732

Опубликована: Авг. 16, 2024

Recent scientific results indicate that diet is the primary source of exposure to endocrine-disrupting chemicals (EDCs) due their use in food processing, pesticides, fertilizers, and migration from packaging food, particularly plastic or canned foods. Although EDCs are not listed on nutrition labels, could inadvertently lead contamination, affecting individuals by inhalation, ingestion, direct contact. The aim our narrative review investigate role phthalates bisphenol A (BPA) foods, assessing risks for precocious puberty (PP) early-onset obesity, which two clinical entities often associated share common pathogenetic mechanisms. diverse outcomes observed across different studies highlight complexity BPA effects human body, both terms early puberty, girls, obesity with its metabolic disruptions. Moreover, independently linked might confound relationship between these pubertal timing. Given potential public health implications, it crucial adopt a precautionary approach, minimizing EDCs, especially vulnerable populations such as children.

Язык: Английский

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Dietary pattern and precocious puberty risk in Chinese girls: a case-control study

Nutrition Journal, Год журнала: 2024, Номер 23(1)

Опубликована: Янв. 31, 2024

Abstract Background The role of dietary intake on precocious puberty remains unclear. This study aimed to investigate the association between amount and frequency risk in Chinese girls. Methods In this case-control study, we enrolled 185 girls age-matched controls. Their was assessed through a semi-quantitative food questionnaire. sociodemographic lifestyle data were collected. associations by conditional logistic regression models. Results After multivariate adjustment, consuming higher red meat associated with (OR = 2.74, 95% CI: 1.25–6.02), while fruit ( P for trend 0.024) vegetable lower 0.002). high protein pattern significantly negatively 0.78, 0.63–0.97), whereas animal fruits remarkably positively 1.36, 1.09–1.69), after adjusting age body mass index. Conclusions High is protective factor against puberty, Attentions should be paid reasonable meat, eggs, children’s daily diet, increase their vegetables, order reduce puberty.

Язык: Английский

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Role of gut commensal bacteria in juvenile developmental growth of the host: insights from Drosophila studies

Animal Cells and Systems, Год журнала: 2023, Номер 27(1), С. 329 - 339

Опубликована: Ноя. 15, 2023

The gut microbiome plays a crucial role in maintaining health variety of organisms, from insects to humans. Further, beneficial symbiotic microbes are believed contribute improving the quality life host. Drosophila is an optimal model for studying host–commensal microbe interactions because it allows convenient manipulation intestinal microbial composition. Fly microbiota has simple taxonomic composition and can be cultivated genetically tracked. This permits functional studies analyses molecular mechanisms underlying their effects on host physiological processes. In this context, we briefly introduce principle juvenile developmental growth Drosophila. Then, discuss current understanding commensal bacteria, such as Lactiplantibacillus plantarum Acetobacter pomorum, fly growth, including specific actions hormones metabolites conserved cellular signaling systems, insulin/insulin-like (IIS) target rapamycin (TOR) pathways. Given similarities tissue function/structure, well high conservation systems between mammals, findings system will have significant implications interaction metazoans.

Язык: Английский

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The study of pubertal stage and age of menarche in girls in Isfahan province, Iran

BMC Pediatrics, Год журнала: 2025, Номер 25(1)

Опубликована: Янв. 31, 2025

The onset age of pubertal changes varies widely among girls and has undergone over time around the world. This study aimed to determine puberty in healthy Iranian living Isfahan province. cross- sectional was conducted 13,886 students aged 6-18 years. They were selected by multistage random cluster sampling from urban rural areas province Iran. Pubertal stage determined according 5-level Tanner stages proposed Marshall Tanner. Trained physicians breast development through both visual inspection palpation, addition, mothers assessed their daughter's pubic hair growth using Tanner's Sexual Maturation Scale (SMS) comparison standard pictures. data analyzed status quo method. Probit regression analysis used evaluate median for each characteristic including menarche, hair. A total with mean (SD) 11.97 (2.9) studied. Overall 6968 (50.2%) experienced menstruation a (95%CI) 12.05(11.88-12.21) years at its onset. 9.89 (95% CI: 9.77 - 10.02) 10.14 9.88- 10.39) 3rd percentile 2 (B2) (PH2) 6.85 6.75 years, respectively, 97th B2 PH2 12.94and 13.54 respectively. According our findings, before should be considered as precocious girls. Our indicated secular trend toward earlier menarche Nationally representative surveys longitudinal studies are necessary exact future international comparisons.

Язык: Английский

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Clinical characteristics and risk factors of female precocious puberty

Medicine, Год журнала: 2025, Номер 104(6), С. e41483 - e41483

Опубликована: Фев. 7, 2025

This study explores the clinical characteristics and risk factors of female precocious puberty. retrospective was conducted on 119 girls with puberty admitted to Pu’er People’s Hospital from January 2022 November 2023 (PP group) normal sexual maturity during same period (normal group). Clinical (including laboratory indicators) general conditions participants in both groups were collected compared. The analyzed using logistic analysis. There statistically significant differences axillary hair growth, early menarche, vaginal mucus appearance, pubic breast development, areola diameter, ovarian volume, uterine bone age, body mass index, height, prolactin, progesterone, estradiol, follicle stimulating hormone, luteinizing hormone levels between 2 ( P < .05). frequent use cosmetics, polluted living environment (chemical pesticide detergents), sleeping light at night, exposure information, consumption fried foods > times/week, snacks parental discord, off-season fruits vegetables, domestic poultry 7 mother’s menarche 12 years, development age ≤ 10 years Logistic analysis confirmed that old, old In practice, targeted prevention control can be implemented based relevant improve physical mental health children.

Язык: Английский

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Early-Life Risks of Central Precocious Puberty

Endocrine Practice, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Язык: Английский

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Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Май 26, 2025

This study aimed to examine trends in the ages of menarche and menopause, related factors, among women Fasa Cohort Study. We analyzed cross-sectional data from cohort, part Persian cohort study, which included 11,000 Iranian adults aged 35 75, with 5311 being women. These were categorized into four age groups: 35-44, 45-54, 55-64, 65-75 years. explored changes mean at along associated using SPSS 22 software applying descriptive statistics, chi-square tests, t-tests, ANOVA, multivariable linear regression. Results indicated a reduction 14.16 13.40 years decline menopause 52.27 40.25 across same groups, both statistically significant (p < 0.001). A relationship was found between factors such as education level, marital status, hypertension, thyroid disease Women without history hypertension experienced 0.84 later than those condition, had delay 0.75 Additionally, each year woman delays having her first child corresponds 0.11-year increase menopause.

Язык: Английский

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Are concepts of adolescence from the Global North appropriate for Africa? A debate

BMJ Global Health, Год журнала: 2023, Номер 8(12), С. e012614 - e012614

Опубликована: Дек. 1, 2023

Язык: Английский

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Breast and Formula Milk and Early Puberty Onset

Children, Год журнала: 2023, Номер 10(10), С. 1686 - 1686

Опубликована: Окт. 14, 2023

Nutrients have an enormous impact on many hormonal systems and aspects of health, nutrition status is a crucial regulator growth pubertal development in children adolescents. In this narrative review, we explore the connection between these feeding methods timing puberty to provide clearer understanding how infant might contribute early puberty. Puberty key stage transition from childhood adulthood represents significant biological milestone growth. Breast milk seems pivotal role onset, mainly due its dynamism, which shape indirectly gut microbiota life, besides direct exposure baby through gut–breast axis. Concerning breast formula their effects onset puberty, protective former occurs. As for potential harmful soy-based formulas isoflavones that they contain, studies reported demonstrate conflicting opinions, underlining need further research topic. A healthy well-nourished diet earliest stages life has preventive overall well-being, reducing risk health problems later life.

Язык: Английский

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A review of dairy food intake for improving health among black children and adolescents in the US

Journal of the National Medical Association, Год журнала: 2024, Номер 116(2), С. 241 - 252

Опубликована: Фев. 15, 2024

Adequate nutrition during childhood and adolescence is crucial for proper neurological, musculoskeletal, immunological, cardiometabolic health development. Yet, disparities among socially underserved racial/ethnic groups in the United States (US) provide significant challenges to achieving adequate these years of rapid growth maturation. For example, Black children adolescents are at greater risk having food insecurity, lower-quality diets, obesity, numerous associated that result from compared their White peers. A growing body evidence indicates improving diet quality critical adolescent well-being, diverse nutritional profile bioactive compounds found within dairy foods may play multiple roles promoting development life stages. Therefore, support overall youth, education implementation efforts needed help this population meet national dietary recommendations 2.5 3 servings per day. Continuing fall short puts nutrient inadequacies can have lifelong impacts on disease development, mental health, life. This review presents state knowledge modifiable strategies involving milk maturation adolescents, with a special focus youth US.

Язык: Английский

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