Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes DOI Open Access
Yanina Timasheva, Zhanna Balkhiyarova, Д. Ш. Авзалетдинова

и другие.

Nutrients, Год журнала: 2024, Номер 16(8), С. 1166 - 1166

Опубликована: Апрель 13, 2024

Disordered eating contributes to weight gain, obesity, and type 2 diabetes (T2D), but the precise mechanisms underlying development of different patterns connecting them specific metabolic phenotypes remain unclear. We aimed identify genetic variants linked behaviour investigate its causal relationships with traits using Mendelian randomization (MR). tested associations between 30 in individuals T2D from Volga-Ural region investigated associated various anthropometric data population large international consortia. detected HTR1D CDKAL1 external eating; HTR2A emotional HTR2A, NPY2R, HTR1F, HTR3A, HTR2C, CXCR2, T2D. Further analyses a separate group revealed significant syndrome (MetS) loci CRP, ADCY3, GHRL, CDKAL1, BDNF, CHRM4, CHRM1, AKT1 genes. MR results demonstrated an inverse relationship glycated haemoglobin levels sample. External influenced such as body mass index, height, hip circumference, waist GWAS cohorts. Our findings suggest that impact both traits.

Язык: Английский

Association of Dietary Intake with Chronic Disease and Human Health DOI Open Access
Domenico Tafuri, Francesca Latino

Nutrients, Год журнала: 2025, Номер 17(3), С. 446 - 446

Опубликована: Янв. 26, 2025

Eating habits are among the major determinants of health, and in most countries world part population suffers from one or more problems related to malnutrition, by default (due an acute chronic lack micronutrients) excess (energy, sugars, fats, deficiencies important [...]

Язык: Английский

Процитировано

0

Association between Diet Quality and Eating Behavior in Type 2 Diabetes Adults: A Cross-Sectional Study DOI Open Access

Ana Maria Gal,

Lidia Iuliana Arhire, Andreea Gherasim

и другие.

Nutrients, Год журнала: 2024, Номер 16(13), С. 2047 - 2047

Опубликована: Июнь 27, 2024

Type 2 diabetes mellitus (T2DM) has become a global epidemic. To effectively control T2DM, individuals must adhere to high-quality diet that encompasses not only healthy dietary patterns but also promotes positive eating behaviors. We conducted cross-sectional study on 314 patients with and we evaluated the quality examined associations between behavior, quality, anthropometric clinical factors in T2DM patients. used Diet Quality Index-International Dutch Eating Behavior Questionnaire assess characteristics. found women had significantly higher than men (61.40 vs. 58.68, p = 0.002) were more prone emotional (2.00 1.53, < 0.001) restrained (2.39 2.05, 0.002). Restrained correlated duration of (r −0.169, 0.003), body mass index 0.182, 0.001), external glycated hemoglobin 0.114, 0.044). Patients vitamin C adequacy score (β 0.117, 0.045). External was positively associated grain 0.208, negatively empty-calorie food moderation −0.125, 0.032). For eating, −0.138, 0.017) fruit 0.125, 0.033). In conclusion, results this provide valuable insight into behavior emphasize importance promoting habits for

Язык: Английский

Процитировано

3

Emotional Eating Is Associated with T2DM in an Urban Turkish Population: A Pilot Study Utilizing Social Media DOI Creative Commons
Aleksandra S. Kristo, Kübra İZLER,

Liel Grosskopf

и другие.

Diabetology, Год журнала: 2024, Номер 5(3), С. 286 - 299

Опубликована: Июль 11, 2024

Lifestyle behaviors and their potential effects on diabetes are being investigated for optimal management. In patients with type 2 mellitus (T2DM), the necessary dietary modifications extend to psychological components consideration. This study aimed determine eating behavior of T2DM different sociodemographic characteristics in an urban Turkish population. The Dutch Eating Behavior Questionnaire (DEBQ) was distributed via social media a smartphone application 108 patients, 58 males 50 females, age 26–40 years (20 individuals, 18.6%) over 40 (88 81.4 %). Basic component factor analysis varimax rotation used item-total correlation coefficient. group exhibited high both restrained emotional (r > 0.8), while participants displayed medium = 0.6–0.8). Compared married single participants, “other” marital status showed significant all categories 0.8). Married were less correlated compared participants. Participants lower education levels 0.8) forms eating, more so those higher attained. Overweight demonstrated moderately 0.4–0.6) restrictive correlation, normal weight obese 0.6–0.8) overweight patients. Regardless demographic factors, when combined, strongest found be other types eating.

Язык: Английский

Процитировано

2

Mendelian Randomization Analysis Identifies Inverse Causal Relationship between External Eating and Metabolic Phenotypes DOI Open Access
Yanina Timasheva, Zhanna Balkhiyarova, Д. Ш. Авзалетдинова

и другие.

Nutrients, Год журнала: 2024, Номер 16(8), С. 1166 - 1166

Опубликована: Апрель 13, 2024

Disordered eating contributes to weight gain, obesity, and type 2 diabetes (T2D), but the precise mechanisms underlying development of different patterns connecting them specific metabolic phenotypes remain unclear. We aimed identify genetic variants linked behaviour investigate its causal relationships with traits using Mendelian randomization (MR). tested associations between 30 in individuals T2D from Volga-Ural region investigated associated various anthropometric data population large international consortia. detected HTR1D CDKAL1 external eating; HTR2A emotional HTR2A, NPY2R, HTR1F, HTR3A, HTR2C, CXCR2, T2D. Further analyses a separate group revealed significant syndrome (MetS) loci CRP, ADCY3, GHRL, CDKAL1, BDNF, CHRM4, CHRM1, AKT1 genes. MR results demonstrated an inverse relationship glycated haemoglobin levels sample. External influenced such as body mass index, height, hip circumference, waist GWAS cohorts. Our findings suggest that impact both traits.

Язык: Английский

Процитировано

1