Positionspapier zum Post-COVID-Syndrom
Deleted Journal,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 3, 2025
The Microbiota-Gut-Brain Axis in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Narrative Review of an Emerging Field
European Journal of Translational Myology,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 12, 2025
The
intricate
relationship
between
gut
microbiota
and
the
brain
has
emerged
as
a
pivotal
area
of
research,
particularly
in
understanding
myalgic
encephalomyelitis/chronic
fatigue
syndrome
(ME/CFS).
This
complex
condition
is
characterized
by
debilitating
fatigue,
cognitive
dysfunction,
wide
array
systemic
manifestations,
posing
significant
challenges
for
diagnosis
treatment.
Recent
studies
highlight
microbiota-gut-brain
axis
crucial
pathway
ME/CFS
pathophysiology,
suggesting
that
alterations
microbial
composition
may
impact
immune
responses,
neurochemical
signaling,
neuronal
health.
narrative
review
systematically
explores
English-language
scholarly
articles
from
January
1995
to
2025,
utilizing
databases
such
PubMed,
Scopus,
Web
Science.
findings
underscore
potential
targeted
therapeutic
interventions
aimed
at
correcting
dysbiosis.
As
research
progresses,
deeper
connection
could
lead
innovative
approaches
managing
ME/CFS,
ultimately
enhancing
quality
life
affected
individuals.
Язык: Английский
The gut microbiome in post-COVID syndrome patients
The Innovation Medicine,
Год журнала:
2025,
Номер
unknown, С. 100123 - 100123
Опубликована: Янв. 1, 2025
<p>Post-COVID
syndrome
(PCS)
is
a
debilitating
condition
that
affects
significant
number
of
COVID-19
survivors
worldwide.
PCS
characterized
by
persistent
symptoms
such
as
fatigue,
shortness
breath,
cognitive
impairment,
and
gastrointestinal
issues.
The
frequent
occurrence
has
prompted
researchers
to
investigate
the
role
gut
microbiota
in
development
progression
PCS.
This
review
synthesizes
findings
from
recent
studies,
providing
comprehensive
overview
changes
both
patients
patients.
Evidence
suggests
can
cause
lasting
alterations
microbiota,
marked
reduced
microbial
diversity,
an
increase
opportunistic
pathogens,
decrease
beneficial
bacteria
support
immune
metabolic
health.
In
addition,
host-microbe
interactions
gut-lung,
gut-brain,
gut-heart
axes
are
explored
understand
impact
microbes
on
systemic
Finally,
potential
diagnostic
therapeutic
strategies
for
discussed,
including
use
probiotics,
prebiotics,
fecal
transplantation
(FMT)
restore
balance
alleviate
symptoms.</p>
Язык: Английский
Addressing Post-Acute COVID-19 Syndrome in Cancer Patients, from Visceral Obesity and Myosteatosis to Systemic Inflammation: Implications in Cardio-Onco-Metabolism
Biomedicines,
Год журнала:
2024,
Номер
12(8), С. 1650 - 1650
Опубликована: Июль 24, 2024
Cardiovascular
disease
and
cancer
are
the
two
leading
causes
of
morbidity
mortality
in
world.
The
emerging
field
cardio-oncology
described
several
shared
risk
factors
that
predispose
patients
to
both
cardiovascular
cancer.
Post-acute
COVID-19
syndrome
is
a
chronic
condition
occurs
many
who
have
experienced
SARS-CoV-2
infection,
mainly
based
on
fatigue,
sedentary
lifestyle,
cramps,
breathing
difficulties,
reduced
lung
performance.
exposes
increased
visceral
adiposity,
insulin
resistance,
myosteatosis,
white
adipose
tissue
content
(surrounded
by
M1
macrophages
characterized
Th1/Th17
phenotype),
which
increases
recurrence.
In
this
review,
main
metabolic
affections
post-acute
at
low
high
cardiomyopathies
will
be
summarized.
Furthermore,
non-pharmacological
strategies
aimed
reducing
atherosclerotic
cardiac
provided,
especially
through
anti-inflammatory
nutrition
with
glycemic
index,
appropriate
physical
activity,
immune-modulating
bioactivities
able
reduce
obesity
improving
insulin-related
signaling
myocardial
metabolism.
Язык: Английский
The Interplay of Microbiota, Long COVID, and Musculoskeletal Pain: A Narrative Review
Deleted Journal,
Год журнала:
2024,
Номер
1(2)
Опубликована: Сен. 1, 2024
Context:
Long
COVID,
a
condition
that
persists
after
the
acute
phase
of
COVID-19,
poses
significant
burden,
with
10
-
45%
recovered
patients
experiencing
persistent
symptoms.
Among
these,
approximately
46%
report
musculoskeletal
pain.
This
narrative
review
explores
potential
connections
between
gut
microbiota,
and
pain,
aiming
to
introduce
new
therapeutic
avenues
preventive
strategies
for
managing
symptoms
in
COVID
patients.
Evidence
Acquisition:
A
comprehensive
search
was
conducted
using
Google
Scholar,
Lens.org,
ConnectedPaper.com
identify
relevant
articles
published
2019
2024.
Keywords
related
pain
were
used.
Articles
selected
based
on
predefined
inclusion
exclusion
criteria,
their
quality
assessed.
Data
from
synthesized
provide
an
overview
interplay
Results:
Recent
research
highlights
role
microbiota
modulating
immune
responses
systemic
inflammation.
Dysbiosis
has
been
linked
severity
progression
COVID-19
persistence
Individuals
often
experience
new-onset
manifestations,
such
as
joint
myalgia,
chronic
Additionally,
dysbiosis
associated
conditions
like
lower
back
knee
osteoarthritis.
suggests
relationship
problems
general
may
also
extend
patients,
indicating
broader
implications
outcomes.
Therapeutic
targeting
probiotics,
prebiotics,
dietary
interventions,
have
shown
promise
these
improving
overall
health
Conclusions:
The
evidence
underscores
importance
understanding
microbiota-musculoskeletal
nexus
COVID.
Gut
contributes
inflammation,
exacerbating
associations
other
emphasize
need
microbiota-targeted
strategies.
Future
should
focus
elucidating
mechanisms
linking
exploring
gut-brain
axis,
developing
personalized
approaches
modulate
microbiota.
Advancing
our
this
can
pave
way
innovative
address
complex
challenges
posed
by
conditions.
Язык: Английский