Lyophilized and Oven-Dried Manilkara zapota Extracts: Characterization and In Vitro, In Vivo, and In Silico Analyses DOI Creative Commons

María Fernanda Rivas-Gastélum,

Patricia Ariadna Galindo-Castillo,

Juan Esparza-Sánchez

и другие.

Plants, Год журнала: 2025, Номер 14(2), С. 216 - 216

Опубликована: Янв. 14, 2025

In this work, extracts from the pulp, peel, and seed of Manilkara zapota were obtained via lyophilization oven drying. Bromatological analyses performed to investigate variabilities in nutritional content fruits after nine post-harvest days. The phytochemical was assessed by gas chromatography flame ionization detector (GC-FID), their biological performance studied using vitro antibacterial antioxidant assays (DPPH ABTS) vivo toxicity models. Molecular docking implemented evaluate interaction between polar compounds chicozapote with receptors involved pathogenesis bacterial strains. Results revealed that water or soluble solids did not vary post-harvest. It demonstrated oven-drying approaches influenced insoluble, total dietary fiber digestible carbohydrates among samples. According GC-FID analysis, it observed methods also altered myristic pentadecanoic acids extracts. noted activities weak due MIC (>1000 μg/mL) IC50 (>2000 values. Still, poor against Artemia salina nauplii. silico evaluation unveiled M. possess a high binding affinity towards DNA gyrase B cultured This study expands scientific evidence regarding influence distinct extraction on nutraceutical native importance considering additional enhance bioactivities.

Язык: Английский

Lyophilized and Oven-Dried Manilkara zapota Extracts: Characterization and In Vitro, In Vivo, and In Silico Analyses DOI Creative Commons

María Fernanda Rivas-Gastélum,

Patricia Ariadna Galindo-Castillo,

Juan Esparza-Sánchez

и другие.

Plants, Год журнала: 2025, Номер 14(2), С. 216 - 216

Опубликована: Янв. 14, 2025

In this work, extracts from the pulp, peel, and seed of Manilkara zapota were obtained via lyophilization oven drying. Bromatological analyses performed to investigate variabilities in nutritional content fruits after nine post-harvest days. The phytochemical was assessed by gas chromatography flame ionization detector (GC-FID), their biological performance studied using vitro antibacterial antioxidant assays (DPPH ABTS) vivo toxicity models. Molecular docking implemented evaluate interaction between polar compounds chicozapote with receptors involved pathogenesis bacterial strains. Results revealed that water or soluble solids did not vary post-harvest. It demonstrated oven-drying approaches influenced insoluble, total dietary fiber digestible carbohydrates among samples. According GC-FID analysis, it observed methods also altered myristic pentadecanoic acids extracts. noted activities weak due MIC (>1000 μg/mL) IC50 (>2000 values. Still, poor against Artemia salina nauplii. silico evaluation unveiled M. possess a high binding affinity towards DNA gyrase B cultured This study expands scientific evidence regarding influence distinct extraction on nutraceutical native importance considering additional enhance bioactivities.

Язык: Английский

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