Gut microbiota in Alzheimer’s disease: Understanding molecular pathways and potential therapeutic perspectives
Ageing Research Reviews,
Год журнала:
2025,
Номер
104, С. 102659 - 102659
Опубликована: Янв. 10, 2025
Язык: Английский
Bridging gap in the treatment of Alzheimer’s disease via postbiotics: Current practices and future prospects
Ageing Research Reviews,
Год журнала:
2025,
Номер
unknown, С. 102689 - 102689
Опубликована: Фев. 1, 2025
Язык: Английский
Postbiotics as a Therapeutic Tool in Alzheimer's Disease: Insights into Molecular Pathways and Neuroprotective Effects
Ageing Research Reviews,
Год журнала:
2025,
Номер
unknown, С. 102685 - 102685
Опубликована: Фев. 1, 2025
Язык: Английский
Nutritional Interventions in Amyotrophic Lateral Sclerosis: From Ketogenic Diet and Neuroprotective Nutrients to the Microbiota-Gut-Brain Axis Regulation
Samira Nabakhteh,
Amir Lotfi,
Arman Afsartaha
и другие.
Molecular Neurobiology,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 17, 2025
Язык: Английский
Use of postbiotics and parabiotics from lactobacilli in the treatment of infectious diarrhea
Microbial Pathogenesis,
Год журнала:
2025,
Номер
204, С. 107580 - 107580
Опубликована: Апрель 12, 2025
Язык: Английский
Role of gut microbiome in suppression of cancers
Gut Microbes,
Год журнала:
2025,
Номер
17(1)
Опубликована: Апрель 20, 2025
The
pathogenesis
of
cancer
is
closely
related
to
the
disruption
homeostasis
in
human
body.
gut
microbiome
plays
crucial
roles
maintaining
its
host
throughout
lifespan.
In
recent
years,
a
large
number
studies
have
shown
that
dysbiosis
involved
entire
process
initiation,
development,
and
prognosis
by
influencing
immune
system
metabolism.
Some
specific
intestinal
bacteria
promote
occurrence
development
cancers
under
certain
conditions.
Conversely,
some
other
suppress
oncogenesis
progression
cancers,
including
inhibiting
delaying
boosting
therapeutic
effect
on
cancers.
promoting
effects
been
comprehensively
discussed
previous
review.
This
article
will
review
latest
advances
mechanisms
suppression,
providing
new
perspective
for
developing
strategies
prevention
treatment.
Язык: Английский
Postbiotics as Antiinflammatory and Immune‐Modulating Bioactive Compounds in Metabolic Dysfunction‐Associated Steatotic Liver Disease
Molecular Nutrition & Food Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 5, 2024
Abstract
Postbiotics,
defined
as
products
or
metabolic
byproducts
secreted
by
live
bacteria
released
after
bacterial
lysis,
are
emerging
promising
therapeutic
agents
for
dysfunction‐associated
steatotic
liver
disease
(MASLD).
This
review
explores
the
antiinflammatory
and
immunomodulatory
properties
of
various
postbiotics,
including
exopolysaccharides,
lipoteichoic
acid,
short‐chain
fatty
acids,
hydrogen
sulfide,
polyamines,
tryptophan
derivatives,
polyphenol
metabolites.
These
compounds
have
demonstrated
potential
in
mitigating
infiltration,
reducing
inflammation,
slowing
fibrosis
progression
preclinical
studies.
Notably,
postbiotics
exert
their
beneficial
effects
modulating
gut
microbiota
composition,
enhancing
intestinal
barrier
function,
optimizing
lipid
metabolism,
hepatic
inflammation
steatosis,
exhibiting
hepatoprotective
properties.
However,
translating
these
findings
into
clinical
practice
requires
well‐designed
trials
to
validate
efficacy
safety,
standardize
production
characterization,
explore
personalized
approaches
synergistic
with
other
modalities.
Despite
challenges,
unique
biological
such
enhanced
safety
compared
probiotics,
make
them
attractive
candidates
developing
novel
nutritional
interventions
targeting
multifactorial
pathogenesis
MASLD.
Further
research
is
needed
establish
utility
improve
systemic
outcomes
this
increasingly
prevalent
condition.
Язык: Английский