Enteric Nervous System and Its Relationship with Neurological Diseases DOI Open Access
María José Luesma Bartolomé,

Liberto López-Marco,

Marta Monzón

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(18), С. 5579 - 5579

Опубликована: Сен. 20, 2024

The enteric nervous system (ENS) is a fundamental component of the gastrointestinal system, composed vast network neurons and glial cells. It operates autonomously but interconnected with central (CNS) through vagus nerve. This communication, known as gut–brain axis, influences bidirectional communication between brain gut. Background/Objectives: study aimed to review neurological pathologies related ENS. Methods: To this end, comprehensive literature search was conducted in “PubMed” database. Articles available “free format” were selected, applying filters “Humans” limiting publications from last ten years. Results: ENS has been linked various diseases, autism spectrum disorder Parkinson’s disease including infection varicella zoster virus (VZV), even sharing CNS. finding suggests that could serve an early diagnostic marker or therapeutic target for diseases. Gastrointestinal symptoms often precede CNS symptoms, ENS’s accessibility aids diagnosis treatment. patients may show intestinal lesions up twenty years before underscoring potential diagnosis. However, challenges include developing standardized protocols uneven distribution dopaminergic Continued research needed explore improving prognosis. Conclusions: promising area development. Nevertheless, it essential continue area, especially gain deeper understanding its organization, function, regenerative capacity.

Язык: Английский

An Anti-Inflammatory Diet and Its Potential Benefit for Individuals with Mental Disorders and Neurodegenerative Diseases—A Narrative Review DOI Open Access
Sophie M. van Zonneveld,

Ellen J. van den Oever,

Benno Haarman

и другие.

Nutrients, Год журнала: 2024, Номер 16(16), С. 2646 - 2646

Опубликована: Авг. 10, 2024

This narrative review synthesizes current evidence regarding anti-inflammatory dietary patterns and their potential benefits for individuals with mental disorders neurodegenerative diseases. Chronic low-grade inflammation is increasingly recognized as a key factor in the etiology progression of these conditions. The examines neuroprotective properties components food groups, focusing on whole foods rather than specific nutrients or supplements. Key showing include fruits vegetables (especially berries leafy greens), grains, legumes, fatty fish rich omega-3, nuts (particularly walnuts), olive oil, fermented foods. These are generally antioxidants, fiber, bioactive compounds that may help modulate inflammation, support gut health, promote neuroprotection. Conversely, ultra-processed foods, red meat, sugary beverages be harmful. Based this evidence, we designed Brain Anti-Inflammatory Nutrition (BrAIN) diet. mechanisms diet modulation microbiota gut-brain axis, regulation inflammatory pathways, reduction oxidative stress, promotion neuroplasticity. BrAIN shows promise an aid to manage disorders.

Язык: Английский

Процитировано

6

Polymicrobial interactions of Helicobacter pylori and its role in the process of oral diseases DOI Creative Commons

Y.F. Fan,

Xi Chen, Tiantian Shan

и другие.

Journal of Oral Microbiology, Год журнала: 2025, Номер 17(1)

Опубликована: Фев. 25, 2025

Objective Helicobacter pylori (H. pylori) infection affects approximately 50% of the global population. The predominant route H. transmission is through oral pathway, making cavity highly significant in its infection. This review focuses on relationship between and diseases, influence microbiota, potential mechanisms involving certain pathogens.

Язык: Английский

Процитировано

0

The Impact of Microbiota on Neurological Disorders: Mechanisms and Therapeutic Implications DOI Open Access
Giuseppe Merra,

Giada La Placa,

Marcello Covino

и другие.

OBM Neurobiology, Год журнала: 2025, Номер 09(01), С. 1 - 12

Опубликована: Фев. 28, 2025

Interactions in the gut-brain crosstalk have led to development of an entirely new concept: "microbiota-gut-brain axis". Microbiota has gained considerable attention relation disorders a more neurological nature, such as neurodevelopmental and neuropsychiatric illnesses like autism spectrum disorder, anxiety, mood disorders. This review aims summarize recent trends insights into role consequences gut microbiota brain health pediatric Dysbiosis may be associated with increased risk diseases that lead different disruptions conditions, including mental issues. During dysbiosis, neuropsychological stress hormones usually affect oxytocin GABA neurons are significantly reduced. Current studies report major depression, cognitive dysfunction closely dysbiosis. In last few years, handful clinical emerged, illustrating potential for bidirectional relationship interactions humans. Perhaps some most crucial investigations demonstrating overlapping relationships human axis come from trials focusing on modulating noting significant correlates. A field is emerging gene-editing technology could represent tool improve microbial characteristics. approach particularly relevant neurodegenerative brain-gut linked loss species and/or high pathobiont load.

Язык: Английский

Процитировано

0

Enteric Nervous System and Its Relationship with Neurological Diseases DOI Open Access
María José Luesma Bartolomé,

Liberto López-Marco,

Marta Monzón

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(18), С. 5579 - 5579

Опубликована: Сен. 20, 2024

The enteric nervous system (ENS) is a fundamental component of the gastrointestinal system, composed vast network neurons and glial cells. It operates autonomously but interconnected with central (CNS) through vagus nerve. This communication, known as gut–brain axis, influences bidirectional communication between brain gut. Background/Objectives: study aimed to review neurological pathologies related ENS. Methods: To this end, comprehensive literature search was conducted in “PubMed” database. Articles available “free format” were selected, applying filters “Humans” limiting publications from last ten years. Results: ENS has been linked various diseases, autism spectrum disorder Parkinson’s disease including infection varicella zoster virus (VZV), even sharing CNS. finding suggests that could serve an early diagnostic marker or therapeutic target for diseases. Gastrointestinal symptoms often precede CNS symptoms, ENS’s accessibility aids diagnosis treatment. patients may show intestinal lesions up twenty years before underscoring potential diagnosis. However, challenges include developing standardized protocols uneven distribution dopaminergic Continued research needed explore improving prognosis. Conclusions: promising area development. Nevertheless, it essential continue area, especially gain deeper understanding its organization, function, regenerative capacity.

Язык: Английский

Процитировано

1