A Potential Link Between Outcome of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) Syndrome in Children and Breastfeeding: A Retrospective Single-Center Cohort Snapshot DOI Creative Commons
Donato Rigante, Marcello Candelli

Children, Год журнала: 2024, Номер 11(12), С. 1559 - 1559

Опубликована: Дек. 23, 2024

Background/Objectives: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome, often referred to as PFAPA may enigmatically recur for an undetermined time in affected children: a potential reason explain its recurring pattern unpredictable period or self-limitation is currently unknown. We explored the relationship between different general, demographic, clinical, laboratory features of children disease evolution over course decade. Methods: have retrospectively screened 150 Italian with history syndrome attending Outpatients Clinic Pediatric Rheumatology our Institution during 2014-2024, all without any recognized chronic diseases: 88 males, 62 females, mean age at onset 2.5 ± 1.7 years, range 0.3-9.4 diagnosis 4.5 2.0 years. The whole cohort patients had been followed up median 5 years (IQR: 4-7). Results Conclusions: After dividing into two groups based on either disappearance persistence symptoms follow-up, we found that positive family fevers, lymphadenopathy, arthralgia, myalgia, breastfeeding more than 6 months were associated febrile attacks least six months. Performing multivariate analysis adjusted sex age, only duration longer higher education level patients' mothers independently resolution symptoms.

Язык: Английский

Factors Contributing to Breastfeeding Cessation Among Arab Women in Israel DOI Open Access
Mahdi Tarabeih, Mohammad Sabbah,

Orsan Yahya

и другие.

Nutrients, Год журнала: 2025, Номер 17(4), С. 735 - 735

Опубликована: Фев. 19, 2025

Background/Objectives: Breastfeeding provides significant health benefits for both infants and mothers, but many women discontinue earlier than recommended. This study investigates the factors contributing to early breastfeeding cessation among Arab in Israel, focusing on multiple factors, such as socio-demographic, work-related, cultural, religious, impacting duration shaping practices. Methods: A cross-sectional survey was conducted 349 women, 65% of whom were Muslim 35% Christian. Logistic regression analyses used identify key predictors cessation. Results: Findings showed that Christian more likely stop their counterparts. Mothers with four or children those balancing work demands at higher risk Contrary expectations, levels religiosity associated a greater likelihood stopping breastfeeding. Additionally, mothers who received personal guidance discontinue, suggesting potential gaps quality support provided. Conclusions: These findings underscore importance tailoring interventions address unique cultural socio-economic challenges faced by Israel. Recommendations include improving quality, workplace culturally sensitive consider role family dynamics. research valuable insights healthcare providers policymakers aiming promote sustained practices diverse populations. The highlights complexity affecting emphasizing need targeted religious influences

Язык: Английский

Процитировано

3
Sexual and Reproductive Health in Overweight and Obesity DOI Creative Commons

Marie Albrecht,

Nina Reitis,

Mirja Pagenkemper

и другие.

Journal of Reproductive Immunology, Год журнала: 2025, Номер 168, С. 104454 - 104454

Опубликована: Фев. 13, 2025

Язык: Английский

Процитировано

0
Human milk oligosaccharide secretion dynamics during breastfeeding and its antimicrobial role: A systematic review DOI
Mohammed Al‐Beltagi

World Journal of Clinical Pediatrics, Год журнала: 2025, Номер 14(2)

Опубликована: Март 18, 2025

BACKGROUND Human milk oligosaccharides (HMOs) are bioactive components of breast with diverse health benefits, including shaping the gut microbiota, modulating immune system, and protecting against infections. HMOs exhibit dynamic secretion patterns during lactation, influenced by maternal genetics environmental factors. Their direct indirect antimicrobial properties have garnered significant research interest. However, a comprehensive understanding dynamics their correlation efficacy remains underexplored. AIM To synthesize current evidence on lactation evaluate roles bacterial, viral, protozoal pathogens. METHODS A systematic search PubMed, Scopus, Web Science, Cochrane Library focused studies investigating natural synthetic HMOs, dynamics, properties. Studies involving human, animal, in vitro models were included. Data HMO composition, temporal patterns, mechanisms action extracted. Quality assessment was performed using validated tools appropriate for study design. RESULTS total 44 included, encompassing research. exhibited 2′-fucosyllactose (2′-FL) lacto-N-tetraose peaking early declining over time, while 3-fucosyllactose (3-FL) increased later stages. demonstrated through pathogen adhesion inhibition, biofilm disruption, enzymatic activity impairment. Synthetic bioengineered 2′-FL 3-FL, structurally functionally comparable to effectively inhibiting pathogens such as Pseudomonas aeruginosa , Escherichia coli Campylobacter jejuni . Additionally, synergistic effects antibiotics, enhancing resistant CONCLUSION vital defense, supporting infant targeting various Both hold potential therapeutic applications, particularly nutrition adjuncts antibiotics. Further research, clinical trials, is essential address gaps knowledge, validate findings, explore broader applicability improving neonatal health.

Язык: Английский

Процитировано

0
Mixed Methods Studies on Breastfeeding: A Scoping Review DOI Open Access
Greyce Pollyne Santos Silva Minarini, Eliane de Fátima Almeida Lima, Karla Crozeta Figueiredo

и другие.

Healthcare, Год журнала: 2025, Номер 13(7), С. 746 - 746

Опубликована: Март 27, 2025

Prenatal and postnatal health guidance, along with women's individual experiences, greatly influences mothers' breastfeeding decisions duration. To understand this better, a methodology combining quantitative qualitative data is essential. Objective: map the scientific production on promotion, protection, support of developed from mixed methods research. Method: A scoping review that followed JBI PRISMA-ScR methodology. The search was carried out in following databases: Medline/PubMed, EMBASE, Cochrane, BVS, CINAHL, Web Science, BDTD. guiding question was: Which studies were using methods? research took place December 2023 to June 2024. Results: Of 3569 found, 36 included, prevalence explanatory sequential approaches. Breastfeeding rates selected remain lower than global recommendations. barriers reported by mothers include biological; emotional; cultural; unfavorable social hospital environment; difficulties clinical management; lack family, friends, professionals, employers; skepticism about benefits breastfeeding. On other hand, main facilitators education counseling during prenatal, childbirth, postpartum periods; intention breastfeed; employer, spouse, professionals. Conclusions: highlighted various issues related rates, barriers, across different contexts cultures worldwide. findings demonstrate employing enables comprehensive nuanced assessment practices evaluation relevant interventions.

Язык: Английский

Процитировано

0
A Potential Link Between Outcome of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) Syndrome in Children and Breastfeeding: A Retrospective Single-Center Cohort Snapshot DOI Creative Commons
Donato Rigante, Marcello Candelli

Children, Год журнала: 2024, Номер 11(12), С. 1559 - 1559

Опубликована: Дек. 23, 2024

Background/Objectives: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome, often referred to as PFAPA may enigmatically recur for an undetermined time in affected children: a potential reason explain its recurring pattern unpredictable period or self-limitation is currently unknown. We explored the relationship between different general, demographic, clinical, laboratory features of children disease evolution over course decade. Methods: have retrospectively screened 150 Italian with history syndrome attending Outpatients Clinic Pediatric Rheumatology our Institution during 2014-2024, all without any recognized chronic diseases: 88 males, 62 females, mean age at onset 2.5 ± 1.7 years, range 0.3-9.4 diagnosis 4.5 2.0 years. The whole cohort patients had been followed up median 5 years (IQR: 4-7). Results Conclusions: After dividing into two groups based on either disappearance persistence symptoms follow-up, we found that positive family fevers, lymphadenopathy, arthralgia, myalgia, breastfeeding more than 6 months were associated febrile attacks least six months. Performing multivariate analysis adjusted sex age, only duration longer higher education level patients' mothers independently resolution symptoms.

Язык: Английский

Процитировано

0