New Frontiers in Nutritional and Therapeutic Interventions for Obesity Phenotypes DOI Creative Commons
Angelo Maria Patti, Rosaria Vincenza Giglio, Marcello Ciaccio

и другие.

Medicina, Год журнала: 2025, Номер 61(4), С. 664 - 664

Опубликована: Апрель 3, 2025

The heterogeneity among patients with obesity is particularly evident in the weight loss response to interventions such as diets, drugs, devices and surgery. Obesity can be “catalogued” into four phenotypes: hungry brain (abnormal satiety for alteration of gut–brain axis), emotional hunger (hedonic eating), gut duration faster gastric emptying) slow burning (slowing metabolic rate). Phenotypes are grafted onto this complexity, recognition which allows personalized medicine increasingly targeted therapies. Although there no standardized treatment protocols, we present management options consisting lifestyle modifications pharmacologic Nutritional advice encouragement adequate physical activity lead increased self-efficacy promote a sense well-being when coupled psychological approaches involving mindful eating. In summary, has complex pathophysiology best addressed through therapeutic process suited phenotype encountered synergy multifactorial interventions.

Язык: Английский

New Frontiers in Nutritional and Therapeutic Interventions for Obesity Phenotypes DOI Creative Commons
Angelo Maria Patti, Rosaria Vincenza Giglio, Marcello Ciaccio

и другие.

Medicina, Год журнала: 2025, Номер 61(4), С. 664 - 664

Опубликована: Апрель 3, 2025

The heterogeneity among patients with obesity is particularly evident in the weight loss response to interventions such as diets, drugs, devices and surgery. Obesity can be “catalogued” into four phenotypes: hungry brain (abnormal satiety for alteration of gut–brain axis), emotional hunger (hedonic eating), gut duration faster gastric emptying) slow burning (slowing metabolic rate). Phenotypes are grafted onto this complexity, recognition which allows personalized medicine increasingly targeted therapies. Although there no standardized treatment protocols, we present management options consisting lifestyle modifications pharmacologic Nutritional advice encouragement adequate physical activity lead increased self-efficacy promote a sense well-being when coupled psychological approaches involving mindful eating. In summary, has complex pathophysiology best addressed through therapeutic process suited phenotype encountered synergy multifactorial interventions.

Язык: Английский

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