Monkeypox: A Comprehensive Review

Viruses, Год журнала: 2022, Номер 14(10), С. 2155 - 2155

Опубликована: Сен. 29, 2022

The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. spread to 104 countries throughout six continents world, with highest burden North America and Europe. etiologic agent, virus (MPXV), been known since 1959 after isolation from infected monkeys, virulence among reported 1970s, mainly endemic West Central Africa. However, re-emerged at an unprecedented pace, particular concern its human-to-human transmissibility community non-endemic regions. As a mitigation effort, healthcare workers, policymakers, general worldwide need be well-informed this relatively neglected viral disease. Here, we provide comprehensive up-to-date overview monkeypox, including following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, management. In addition, current review discusses preventive control measures, latest vaccine developments, future research areas re-emerging that was declared as emergency international concern.

Язык: Английский

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Assessing Healthcare Workers’ Knowledge and Their Confidence in the Diagnosis and Management of Human Monkeypox: A Cross-Sectional Study in a Middle Eastern Country

Healthcare, Год журнала: 2022, Номер 10(9), С. 1722 - 1722

Опубликована: Сен. 8, 2022

The ongoing multi-country human monkeypox (HMPX) outbreak was declared as a public health emergency of international concern. Considering the key role healthcare workers (HCWs) in mitigating HMPX outbreak, we aimed to assess their level knowledge and confidence diagnosis management disease, besides assessment attitude towards emerging virus infections from conspiracy point view. An online survey distributed among HCWs Jordan, Middle Eastern country, during May−July 2022 using questionnaire published previous study university students schools Jordan. sample comprised 606 HCWs, with about two-thirds being either physicians (n = 204, 33.7%) or nurses 190, 31.4%). Four out 11 items had <50% correct responses only 33.3% respondents having that vaccination is available prevent HMPX. A majority 356, 58.7%) strongly agreed, agreed somewhat spread related male homosexuals. Confidence ability based on diagnostic tests reported by 50.2% respondents, while levels were lower for manage (38.9%) diagnose (38.0%) cases current skills. Higher found compared nurses. endorsement beliefs emergence associated knowledge, belief homosexuals spread, levels. highlighted gaps regarding Jordan well lack Raising awareness disease needed urgently considering rapid escalation number worldwide East. homosexuals’ necessitates proper intervention measures stigma discrimination this risk group. adoption conspiratorial widely prevalent issue needs be addressed accurate its potential harmful impact.

Язык: Английский

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Monkeypox Knowledge and Vaccine Hesitancy of Czech Healthcare Workers: A Health Belief Model (HBM)-Based Study

Vaccines, Год журнала: 2022, Номер 10(12), С. 2022 - 2022

Опубликована: Ноя. 26, 2022

The recent human monkeypox virus (HMPXV) outbreak in non-endemic countries that started May 2022 has raised concerns among public health authorities worldwide. Healthcare workers (HCWs) play a decisive role during epidemics transmitting accurate information to the and motivating them pursue protective behaviours, including immunisation.

Язык: Английский

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Knowledge and vaccination intention of monkeypox in China's general population: A cross-sectional online survey

Travel Medicine and Infectious Disease, Год журнала: 2022, Номер 52, С. 102533 - 102533

Опубликована: Дек. 18, 2022

Public awareness of monkeypox is critical in the fight against this infectious disease. However, at present a survey Chinese population on lacking. This study was conducted to compensate for lack knowledge and identify vaccination intention assessment China. The questionnaire comprised 20 items with following three aspects: basic information, knowledge, willingness vaccinate or pay. For study, 521 valid respondents were recruited. Utilizing logistic regression, researchers identified factors related intentions. average total score 5.6 (score range 0–10), 309 (59.3%) participants categorized as having greater based 6. Most (76.4%) willing accept vaccination. acceptable cost vaccine CNY261.2. Factors such level education, working within healthcare profession knowledge. An increased higher vaccinate. Participants who pay more vaccines included those high incomes, suffered from chronic diseases, workers. had relatively demonstrated receive vaccine.

Язык: Английский

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Monkeypox Cross-Sectional Survey of Knowledge, Attitudes, Practices, and Willingness to Vaccinate among University Students in Pakistan

Vaccines, Год журнала: 2022, Номер 11(1), С. 97 - 97

Опубликована: Дек. 31, 2022

This study aimed to explore knowledge, attitude, perceptions, and willingness regarding vaccination among university students in Pakistan. cross-sectional was carried out using an open online self-administered survey via Google Forms. The data were collected between the 15 30 of October 2022. A total 946 respondents participated study, which majority female (514, 54.3%). Most belonged a medical background, specifically pharmaceutical sciences. did not know about monkeypox before 2022 (646, 68.3%). Regarding overall knowledge monkeypox, most had average (726, 76.7%), with very few having good (60, 6.3%). attitudes towards neutral (648, 68.5%). There significant association Monkeypox type academic degree (p < 0.001), discipline region 0.001). vaccinate population (67.7%). current pointed that respondents, considerable gaps aspects. attitude neutral. Further, strongly associated degree, discipline, respondents. Our findings emphasize need raise public awareness by educating on virus. will improve adherence preventative recommendations.

Язык: Английский

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Monkeypox Vaccine Hesitancy in French Men Having Sex with Men with PrEP or Living with HIV in France

Vaccines, Год журнала: 2022, Номер 10(10), С. 1629 - 1629

Опубликована: Сен. 28, 2022

People with pre-exposure prophylaxis (PrEP) or living HIV are a high-risk population for monkeypox virus (MPXV) infection. It is important to achieve high MPXV vaccination coverage rates in this group. This project used self-reporting assess vaccine hesitancy the smallpox and acceptance among men having sex PrEP HIV. In total, 52 (33.6%) participants 155 declared their be vaccinated against MPXV. Moreover, 20.7% patients hesitant attitude towards compared 40.2% of patients, p = 0.013. difference remained not significant after adjustment age (p 0.119) both number different sexual partners 0.406). Among people, those who expressed concerns about people getting more vaccines than needed 0.012) were less likely accept vaccination, whereas an increased during previous month was significantly associated 0.034). being infected by < 0.001), that should compulsory at risk 0.001) 0.018) higher vaccination. Our results suggest strategy would efficient France communication emphasizing benefits potential infection health people. Other preventive actions implemented, including reduction partners.

Язык: Английский

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Monkeypox: Immune response, vaccination and preventive efforts

Narra J, Год журнала: 2022, Номер 2(3)

Опубликована: Окт. 21, 2022

Infectious threats to humans are continuously emerging. The 2022 worldwide monkeypox outbreak is the latest of these with virus rapidly spreading 106 countries by end September 2022. burden ongoing manifested 68,000 cumulative confirmed cases and 26 deaths. Although usually a self-limited disease, patients can suffer from extremely painful skin lesions complications occur reported mortalities. antigenic similarity between smallpox (variola virus) be utilized prevent using vaccines; treatment also based on antivirals initially designed treat smallpox. However, further studies needed fully decipher immune response evasion mechanisms. In this review we provide an up-to-date discussion current state knowledge regarding special focus innate response, mechanisms vaccination against virus.

Язык: Английский

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The willingness of Chinese healthcare workers to receive monkeypox vaccine and its independent predictors: A cross‐sectional survey

Journal of Medical Virology, Год журнала: 2022, Номер 95(1)

Опубликована: Ноя. 11, 2022

The global monkeypox outbreak in 2022 has severely affected the life and health of people. Currently, partial smallpox vaccines have been approved for prevention. Considering potential occupational risks infection among healthcare workers (HCWs), this study explored willingness Chinese HCWs to receive vaccine analyzed factors influencing their decision. We conducted an online cross-sectional survey 10 hospitals from May 30th, August 1st, 2022. Specifically, a self-report questionnaire was administered evaluate attitude acceptance toward vaccine, followed by multivariate logistic regression analysis determine independent predictors vaccination. included 1032 participants, whom 90.12% expressed vaccination (vaccine hesitancy rate = 9.88%). Univariate showed that 11 variables differed significantly between groups. Multivariate demonstrated age 30-40 years (odds ratio [OR] 0.504, 95% confidence interval [CI]: 0.284-0.893, p 0.019 vs. <30 old), working secondary hospital (OR 0.449, CI: 0.249-0.808, tertiary hospital), considering necessary controlling 4.135, 2.109-8.106, < 0.001 not it necessary), pay 2.125, 1.206-3.745, 0.009 no pay), implementation mandatory 1.990, 1.023-3.869, 0.043 recommending family members friends take 13.847, 7.487-25.609, recommending) were crucial monkeypox-related This evaluated rates found mainly correlated age, level, Therefore, promote absorption, we recommend expanding publicity, formulating reasonable policies, improving recognition vaccines.

Язык: Английский

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Knowledge, Attitude and Worry in the Kurdistan Region of Iraq during the Mpox (Monkeypox) Outbreak in 2022: An Online Cross-Sectional Study

Vaccines, Год журнала: 2023, Номер 11(3), С. 610 - 610

Опубликована: Март 8, 2023

The rapid spread of monkeypox (mpox) has been declared as a public health emergency international concern (PHEIC). present study aimed to assess the knowledge, attitude, and worry levels general population in Kurdistan region Iraq regarding ongoing mpox multi-country outbreak. An online cross-sectional survey was conducted between 27–30 July 2022, using convenience sampling method. questionnaire adapted from previous studies addressing same topic. independent Student’s t-test, one-way ANOVA, logistic regression were used possible factors associated with toward mpox. A total 510 respondents included final analysis. participants showed moderate level neutral attitude towards mpox, relatively level. analysis that age, gender, marital status, religion, education, place residence knowledge; however, significant variables multivariate residential area. Gender area attitudes mpox; gender areas. influenced by residence, yet educational level, In conclusion, Kurdish had about Considering continuous rise cases several countries, its risk pandemic amid COVID-19 pandemic, proactive control measures, adequate disease prevention strategies, preparedness plans need be formulated immediately implemented tackle appearance fears among people, safeguard mental public.

Язык: Английский

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Previous Vaccination History and Psychological Factors as Significant Predictors of Willingness to Receive Mpox Vaccination and a Favorable Attitude towards Compulsory Vaccination

Vaccines, Год журнала: 2023, Номер 11(5), С. 897 - 897

Опубликована: Апрель 25, 2023

During the ongoing multi-country monkeypox (Mpox) outbreak, healthcare workers (HCWs) have represented a key group in mitigating disease spread. The current study aimed to evaluate attitude of nurses and physicians Jordan towards Mpox vaccination, as well their compulsory vaccination against coronavirus 2019 (COVID-19), influenza, Mpox. An online survey was distributed January 2023 based on previously validated 5C scale for psychological determinants vaccination. Previous behavior assessed by inquiring about history getting primary booster COVID-19 influenza vaccine uptake during COVID-19, any uptake. sample consisted 495 respondents: (

Язык: Английский

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