Controlling Pandemic COVID-19 DOI
David M. Morens, Gagandeep Kang

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 231 - 251

Опубликована: Ноя. 24, 2024

Abstract Rarely has eradication of a newly emerging infectious disease been considered while the was in its earliest stages emergence, when properties causative agent remained uncharacterized, pathogenetic mechanisms had yet to be understood, and epidemiologic features such as transmissibility nature protective immunity were still continually changing. Nevertheless, because COVID-19, caused by SARS-CoV-2, is among three deadliest pandemics past few centuries (the others being 1918 influenza pandemic HIV/AIDS pandemic, recognized 1981), potential eradicated must considered, especially since 2003 SARS related virus, disappeared. This review compares epidemiologic, immunologic, virologic SARS-CoV-2 with those other human respiratory viruses eradicable ineradicable. The chapter concludes that based on viral host responses it, COVID-19 not existing tools. However, using spread India for context, suggests there much can done control associated severe mortality without discusses this important challenge science, public health, medicine future.

Язык: Английский

The Potential Use of Peptides in the Fight against Chagas Disease and Leishmaniasis DOI Creative Commons
Hayelom Berhe Dagnaw,

Mahesh Kumar Cinthakunta Sridhar,

Mulate Zerihun

и другие.

Pharmaceutics, Год журнала: 2024, Номер 16(2), С. 227 - 227

Опубликована: Фев. 4, 2024

Chagas disease and leishmaniasis are both neglected tropical diseases that affect millions of people around the world. Leishmaniasis is currently second most widespread vector-borne parasitic after malaria. The World Health Organization records approximately 0.7-1 million newly diagnosed cases each year, resulting in 20,000-30,000 deaths. Also, 25 worldwide at risk an estimated 6 infected with

Язык: Английский

Процитировано

5

Therapeutic potential of antimicrobial peptides against pathogenic protozoa DOI
Corina Lobato Hagemann, Alexandre José Macêdo, Tiana Tasca

и другие.

Parasitology Research, Год журнала: 2024, Номер 123(2)

Опубликована: Фев. 1, 2024

Язык: Английский

Процитировано

4

Biotechnological Innovations for Tropical Disease Management DOI
Matthew Chidozie Ogwu, Sylvester Chibueze Izah

Health information science, Год журнала: 2025, Номер unknown, С. 237 - 262

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

A novel prolixicin identified in common bed bugs with activity against both bacteria and parasites DOI Creative Commons

Sanam Meraj,

Arshvir Singh Dhari,

Emerson Mohr

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Июнь 15, 2024

Язык: Английский

Процитировано

3

Targeting Leishmania Promastigotes and Amastigotes Forms through Amino Acids and Peptides: A Promising Therapeutic Strategy DOI

Charmante Registre,

Luciana Miranda Silva,

Farah Registre

и другие.

ACS Infectious Diseases, Год журнала: 2024, Номер 10(8), С. 2467 - 2484

Опубликована: Июль 1, 2024

Millions of people worldwide are affected by leishmaniasis, caused the Leishmania parasite. Effective treatment is challenging due to biological complexity parasite, drug toxicity, and increasing resistance conventional drugs. To combat this disease, development specific strategies target selectively eliminate parasite crucial. This Review highlights importance amino acids in developmental stages as a factor determining whether infection progresses or suppressed. It also explores use peptides alternatives control novel targeted treatments. While these show promise for more effective treatment, further studies address remaining challenges imperative.

Язык: Английский

Процитировано

2

Mitigation strategy for neglected zoonotic diseases and antimicrobial resistance DOI
Olivier Sparagano

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 345 - 348

Опубликована: Ноя. 22, 2024

Язык: Английский

Процитировано

0

Controlling Pandemic COVID-19 DOI
David M. Morens, Gagandeep Kang

Oxford University Press eBooks, Год журнала: 2024, Номер unknown, С. 231 - 251

Опубликована: Ноя. 24, 2024

Abstract Rarely has eradication of a newly emerging infectious disease been considered while the was in its earliest stages emergence, when properties causative agent remained uncharacterized, pathogenetic mechanisms had yet to be understood, and epidemiologic features such as transmissibility nature protective immunity were still continually changing. Nevertheless, because COVID-19, caused by SARS-CoV-2, is among three deadliest pandemics past few centuries (the others being 1918 influenza pandemic HIV/AIDS pandemic, recognized 1981), potential eradicated must considered, especially since 2003 SARS related virus, disappeared. This review compares epidemiologic, immunologic, virologic SARS-CoV-2 with those other human respiratory viruses eradicable ineradicable. The chapter concludes that based on viral host responses it, COVID-19 not existing tools. However, using spread India for context, suggests there much can done control associated severe mortality without discusses this important challenge science, public health, medicine future.

Язык: Английский

Процитировано

0