Risk factors and risk‐indicating model for early‐onset neonatal sepsis after preterm prelabor rupture of membranes: A historical cohort study DOI Creative Commons
Brynhildur Tinna Birgisdottir, Tomas Andersson, Ingela Hulthén Varli

и другие.

Acta Obstetricia Et Gynecologica Scandinavica, Год журнала: 2025, Номер unknown

Опубликована: Июнь 1, 2025

Abstract Introduction Early‐onset neonatal sepsis (EONS) is an important cause of morbidity and mortality strongly associated with intra‐amniotic infection. The risk infection increases after preterm prelabor rupture membranes (PPROM). Better tools are needed for monitoring women PPROM identifying those at high EONS so that intervention can be made timely. This study aimed to identify antepartum factors in a population develop risk‐indicating model. Material Methods We performed historical cohort on pregnancies delivering between gestational weeks 24 + 0 33 6 Stockholm, Sweden. Using logistic regression, we evaluated the outcome maternal background characteristics, symptoms signs, cardiotocography. combined variables into model estimated its performance by calculating sensitivity, specificity, accuracy, positive negative predictive values, likelihood ratio, area under ROC curve. Results included 709 their neonates, out which 29 developed EONS. Variables most were diabetes (OR 4.37, 95% CI 1.41–13.56), temperature ≥ 38°C 6.42, 2.94–14.02), urinary or vaginal/cervical culture 2.62, 1.14–6.03), cardiotocography parameters. Fetal baseline frequency above 160 bpm was 3.75 times increased (95% 1.51–9.33). Meanwhile, short‐term variation negatively risk, value below 4 ms had 4.17 1.77–9.83). A combining mentioned curve 0.7348. better indicating than clinicians' suspicion Conclusions Maternal diabetes, fever, culture, fetal tachycardia, decreasing population. these high‐risk

Язык: Английский

Risk factors and risk‐indicating model for early‐onset neonatal sepsis after preterm prelabor rupture of membranes: A historical cohort study DOI Creative Commons
Brynhildur Tinna Birgisdottir, Tomas Andersson, Ingela Hulthén Varli

и другие.

Acta Obstetricia Et Gynecologica Scandinavica, Год журнала: 2025, Номер unknown

Опубликована: Июнь 1, 2025

Abstract Introduction Early‐onset neonatal sepsis (EONS) is an important cause of morbidity and mortality strongly associated with intra‐amniotic infection. The risk infection increases after preterm prelabor rupture membranes (PPROM). Better tools are needed for monitoring women PPROM identifying those at high EONS so that intervention can be made timely. This study aimed to identify antepartum factors in a population develop risk‐indicating model. Material Methods We performed historical cohort on pregnancies delivering between gestational weeks 24 + 0 33 6 Stockholm, Sweden. Using logistic regression, we evaluated the outcome maternal background characteristics, symptoms signs, cardiotocography. combined variables into model estimated its performance by calculating sensitivity, specificity, accuracy, positive negative predictive values, likelihood ratio, area under ROC curve. Results included 709 their neonates, out which 29 developed EONS. Variables most were diabetes (OR 4.37, 95% CI 1.41–13.56), temperature ≥ 38°C 6.42, 2.94–14.02), urinary or vaginal/cervical culture 2.62, 1.14–6.03), cardiotocography parameters. Fetal baseline frequency above 160 bpm was 3.75 times increased (95% 1.51–9.33). Meanwhile, short‐term variation negatively risk, value below 4 ms had 4.17 1.77–9.83). A combining mentioned curve 0.7348. better indicating than clinicians' suspicion Conclusions Maternal diabetes, fever, culture, fetal tachycardia, decreasing population. these high‐risk

Язык: Английский

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