Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectives DOI Creative Commons
Snežana M Jovičić

International Journal of Immunopathology and Pharmacology, Год журнала: 2024, Номер 38

Опубликована: Янв. 1, 2024

Enzyme Che plays an essential role in cholinergic and non-cholinergic functions. It is present the fertilized/unfertilized eggs sperm of different species. Inclusion criteria for data collection from electronic databases NCBI Google Scholar are enzyme AChE/BChE, therapy, genomic organization gene transcription, structure, biogenesis, transport, processing localization, molecular signaling biological function, polymorphism influencing factors. acts as a receptor during hematopoiesis, protein adhesion, amyloid fiber formation, neurite outgrowth, bone development, maturation, explaining activity out synaptic neurotransmission. Polymorphism genes correlates to various diseases diverse drug responses. In particular, change accompanies cancer, neurodegenerative, cardiovascular disease. Literature knowledge indicates importance inhibitors that influence biochemical pathways disease treatment, organization, processing, localization enzyme. changes indicate possibility efficient new inhibitor target mechanisms research areas.

Язык: Английский

Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectives DOI Creative Commons
Snežana M Jovičić

International Journal of Immunopathology and Pharmacology, Год журнала: 2024, Номер 38

Опубликована: Янв. 1, 2024

Enzyme Che plays an essential role in cholinergic and non-cholinergic functions. It is present the fertilized/unfertilized eggs sperm of different species. Inclusion criteria for data collection from electronic databases NCBI Google Scholar are enzyme AChE/BChE, therapy, genomic organization gene transcription, structure, biogenesis, transport, processing localization, molecular signaling biological function, polymorphism influencing factors. acts as a receptor during hematopoiesis, protein adhesion, amyloid fiber formation, neurite outgrowth, bone development, maturation, explaining activity out synaptic neurotransmission. Polymorphism genes correlates to various diseases diverse drug responses. In particular, change accompanies cancer, neurodegenerative, cardiovascular disease. Literature knowledge indicates importance inhibitors that influence biochemical pathways disease treatment, organization, processing, localization enzyme. changes indicate possibility efficient new inhibitor target mechanisms research areas.

Язык: Английский

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