Incorporation of essential oils in polymeric films for biomedical applications
International Journal of Biological Macromolecules,
Год журнала:
2024,
Номер
269, С. 132108 - 132108
Опубликована: Май 6, 2024
Язык: Английский
Chemical Characterization and Antimicrobial Activity of Essential Oils and Nanoemulsions of Eugenia uniflora and Psidium guajava
Antibiotics,
Год журнала:
2025,
Номер
14(1), С. 93 - 93
Опубликована: Янв. 14, 2025
Background/Objectives:
This
study
aimed
to
develop
gel
nanoemulsions
(NEs)
of
Brazilian
essential
oils
(EOs)
from
Eugenia
uniflora
and
Psidium
guajava,
as
well
perform
chemical
characterization
investigate
the
antimicrobial
activity
EOs
NEs.
Results/Conclusions:
The
main
compounds
E.
EO
were
curzerene
(34.80%)
germacrene
B
(11.92%),
while
those
P.
guajava
β-caryophyllene
(25.92%),
β-selinene
(22.64%),
γ-selinene
(19.13%).
NEs
had
droplet
sizes
105.30
99.50
nm
polydispersity
index
(PDI)
values
0.32
0.43,
respectively.
remained
stable
for
30
days
storage
at
25
°C,
with
104.7
103.8
nm,
PDI
below
0.50,
no
phase
separation.
NE
exhibited
inhibition
zones
ranging
8.41
15.13
mm
against
Gram-positive
bacterium
Staphylococcus
aureus
Gram-negative
bacteria
Pseudomonas
aeruginosa,
Klebsiella
pneumoniae,
Acinetobacter
baumannii.
Additionally,
showed
largest
Candida
albicans
(20.97
mm)
krusei
(15.20
mm),
along
low
minimum
inhibitory
concentration
(MIC)
(0.54–1.22
mg/mL)
minimal
bactericidal
(MBC)
(4.84–11.02
these
pathogenic
yeasts.
demonstrated
MIC
(1.26
MBC
(11.35
C.
krusei.
time–growth
assay
also
suggests
effectiveness
tested
pathogens
S.
coli,
highlighting
its
potential
a
novel
alternative
therapeutic
agent.
Язык: Английский
Enhancing the efficacy of monolaurin against SARS-CoV-2 and influenza A (H1N1) with a nanoemulsion formulation
OpenNano,
Год журнала:
2024,
Номер
17, С. 100207 - 100207
Опубликована: Апрель 27, 2024
Monolaurin
was
utilized
to
formulate
temperature-driven
phase
inversion
nanoemulsions
containing
lesser
galangal
essential
oil,
fixed
and
Cremophor
RH40,
with
aim
for
eradicating
enveloped
viruses.
Results
showed
that
the
droplet
size
of
nanoemulsion
depended
on
oil–fixed
oil
ratio,
monolaurin
concentration,
concentration.
Nanoemulsions
prepared
from
oil–perilla
(60:40)
exhibited
approximately
50-nm
nanosized
droplets
high
entrapment
efficiency
(98.68%
±
2.45%).
After
storage
at
25°C
1
year,
did
not
vary
significantly
initial
size,
content
>95%,
indicating
good
physical
chemical
stability.
The
located
oil–water
interface
as
indicated
by
a
two-dimensional
nuclear
Overhauser
effect
magnetic
resonance
spectroscope
computer
simulation.
0.2%
w/v
inhibited
SARS-CoV-2
influenza
A
(H1N1)
viruses
efficacy
more
than
3
log
reduction
(99.90%)
low
cytotoxicity.
Hence,
can
successfully
eradicate
viruses,
especially
(H1N1).
Язык: Английский