Nanotoxicology: developments and new insights DOI

Henry N. Abonyi,

Ikechukwu Emmanuel Peter, Akachukwu Marytheresa Onwuka

и другие.

Nanomedicine, Год журнала: 2024, Номер 20(2), С. 225 - 241

Опубликована: Дек. 26, 2024

The use of nanoparticles (NPs) in treatment diseases have increased exponentially recently, giving rise to the science nanomedicine. safety these NPs humans has also led nanotoxicology. Due a dearth both readily available models and precise bio-dispersion characterization techniques, nanotoxicological research obviously been constrained. However, ensuing years were notable for emergence improved synthesis methods tools. Major advances made linking certain physical variables, paralleling improvements size, shape, or coating factors resulting physiological reactions. Although significant progress contribution development nanotoxicology, however, it faces numerous difficulties technical constraints distinct from those conventional toxicological assessment as attempts improve therapeutic effects medicines. Determining thorough standards, standardizing dosimetry, assessing kinetics ions dissolving enhancing accuracy vitro-in vivo correlation efficiency, defining restrictions on exposure protection are some most important pressing concerns. This article will explore past advancement potential prospects standard models, emphasizing findings earlier studies examining current challenges, insight way forward.

Язык: Английский

The role of biomaterials-based scaffolds in advancing skin tissue construct DOI Creative Commons

Komal Sindhi,

Ravindra Babu Pingili,

Vishal Beldar

и другие.

Journal of Tissue Viability, Год журнала: 2025, Номер 34(2), С. 100858 - 100858

Опубликована: Янв. 14, 2025

Despite extensive clinical studies and therapeutic interventions, addressing significant skin wounds remains challenging, necessitating novel approaches for effective regeneration therapy. In the current review, we analyzed evaluated application, advancements, future directions of biomaterials-based scaffolds tissue construct. addition, investigated role other biological substitutes in promoting wound healing regeneration. The review highlights impact biomaterial-based on healing. After presenting physiological process regeneration, emphasizes different biochemical components Subsequently, it delves into engineering. Recent advancements nanotechnology are also highlighted with a specific focus utilization nanomaterials enhancing healing, facilitating reconstruction. Biomaterial have emerged as potential intervention forming foundation These scaffolds, intricate three-dimensional frameworks, serve carriers cells, medications, genes, their delivery body. integration degradable porous cells offers promising avenue repair. Biomaterials play crucial engineering, providing temporary mechanical support cellular processes to augment

Язык: Английский

Процитировано

2

Neuroinflammation and Schizophrenia: New Therapeutic Strategies through Psychobiotics, Nanotechnology, and Artificial Intelligence (AI) DOI Open Access
Freiser Eceomo Cruz Mosquera,

Maria Camila Guevara-Montoya,

Valentina Serna-Ramirez

и другие.

Journal of Personalized Medicine, Год журнала: 2024, Номер 14(4), С. 391 - 391

Опубликована: Апрель 6, 2024

The prevalence of schizophrenia, affecting approximately 1% the global population, underscores urgency for innovative therapeutic strategies. Recent insights into role neuroinflammation, gut–brain axis, and microbiota in schizophrenia pathogenesis have paved way exploration psychobiotics as a novel treatment avenue. These interventions, targeting gut microbiome, offer promising approach to ameliorating psychiatric symptoms. Furthermore, advancements artificial intelligence nanotechnology are set revolutionize psychobiotic development application, enhance their production, precision, effectiveness. This interdisciplinary heralds new era management, potentially transforming patient outcomes offering beacon hope those afflicted by this complex disorder.

Язык: Английский

Процитировано

15

Insights of biopolymeric blended formulations for diabetic wound healing DOI
Ameya Sharma, Divya Dheer, Vivek Puri

и другие.

International Journal of Pharmaceutics, Год журнала: 2024, Номер 656, С. 124099 - 124099

Опубликована: Апрель 16, 2024

Язык: Английский

Процитировано

10

Sustainable dressings for wound healing DOI Creative Commons
Munishwar N. Gupta,

Avinash Rangaraju,

Premlata Ambre

и другие.

Deleted Journal, Год журнала: 2025, Номер 2(1)

Опубликована: Янв. 2, 2025

Abstract The field of chronic wound care has been rapidly evolving. With a market size for wounds in billions USD, this is not an insignificant area to encourage more sustainable practices and processes. sourcing starting materials dressings from renewable resources the first crucial step ensuring that environmental impact minimized. Next important choice select methodologies accordance with principles green chemistry. This involves utilizing solvents as reaction media chemical processes preparing dressing materials. In many cases, like production hydrogels, crosslinking reagents are often employed. These can be, general, easily replaced by enzymes peroxidases, tyrosinases sortases. Process intensification strategies have emerged powerful approach ensure economy sustainability at large scale. Use microwave radiations ultrasonication instead heat accelerate rates helps cases inject wounds. review attempts highlight ongoing efforts future possibilities development cost-effective methods. Graphical

Язык: Английский

Процитировано

1

Laser-fabricated Metal Oxide Core–shell Nanoparticles for Biomedical Applications: a Mini Review DOI

Sarah M. Talib,

Adawiya J. Haider, Sharafaldin Al-Musawi

и другие.

Plasmonics, Год журнала: 2025, Номер unknown

Опубликована: Фев. 3, 2025

Язык: Английский

Процитировано

1

A chondroitin sulfate-based temperature-responsive hydrogel with antimicrobial properties for epidermal wound repair in diabetic patients DOI

Jiaxin Han,

Huimin Liu, Junfang Cheng

и другие.

European Polymer Journal, Год журнала: 2024, Номер unknown, С. 113588 - 113588

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

5

Nanomedicine and Its Role in Surgical Wound Infections: A Practical Approach DOI Creative Commons
Malak Bentaleb,

Mohammed Abdulrahman,

Marcelo Augusto Fontenelle Ribeiro

и другие.

Bioengineering, Год журнала: 2025, Номер 12(2), С. 137 - 137

Опубликована: Янв. 31, 2025

Surgical wound infections are a major cause of postoperative complications, contributing to surgical morbidity and mortality. With the rise antibiotic-resistant pathogens, it is crucial develop new innovative materials manage using methods that facilitate drug delivery agents rely on other than antimicrobials. Nanoparticles, in particular, have captured researchers' interest recent years due their effectiveness care. They can be classified into three main types: inorganic nanoparticles, lipid-based polymeric nanoparticles. Several studies demonstrated these technologies enhancing wound-healing times reducing bacterial burden. However, further research essential thoroughly evaluate safety toxicity before they integrated routine practice.

Язык: Английский

Процитировано

0

Sustainable streptomycin-based Ag nanoparticle synthesis and study of the cytotoxicity DOI
Balázs Kakasi,

Flóra Judit Varga,

Márk Hopotószki

и другие.

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Язык: Английский

Процитировано

0

Systematic review of antibacterial potential in calcium oxide and silicon oxide nanoparticles for clinical and environmental infection control DOI Creative Commons

Hend Algadi,

Mohammed Abdelfatah Alhoot,

Laith A. Yaaqoob

и другие.

Journal of Applied Biomedicine, Год журнала: 2025, Номер unknown

Опубликована: Фев. 10, 2025

A substantial threat to worldwide health, the proliferation of antibiotic-resistant bacteria compels researchers seek innovative antibacterial substances. This systematic review assesses role nanoparticles, particularly Calcium oxide and Silicon in infection control. The article examines mechanisms by which these nanoparticles act against various evaluates their potential as novel agents control strategies. literature search from 2015 2024 encompassing Web Science, PubMed, Wiley, Science Direct, Google Scholar, yielded 70 publications meeting criteria. comprehensive methodology provides a thorough understanding capabilities limitations agents. aims build solid foundation for utilization addressing obstacles presented antibiotic resistance combining data investigations. Additionally, it explore safety environmental implications associated with use clinical settings, providing analysis that may contribute future studies real-world applications field antimicrobial technology.

Язык: Английский

Процитировано

0

Integrating advanced synthesis techniques and AI-driven approaches with nanofiber technology: A state-of-the-art approach to wound care management DOI Creative Commons
Nisha Shankhwar, Awadhesh Kumar Verma, Ashab Noumani

и другие.

Next Nanotechnology, Год журнала: 2025, Номер 8, С. 100147 - 100147

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0