RGD-based self-assembling nanodrugs for improved tumor therapy DOI Creative Commons
Bin Wang, Dongmei Tang,

Jianqiao Cui

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Окт. 1, 2024

RGD-based self-assembling nanodrugs are a promising advancement in targeted cancer therapy, combining the specificity of RGD peptides with benefits nanotechnology. These enhance tumor targeting and cellular uptake while reducing off-target effects. facilitate self-assembly stable nanostructures, ensuring efficient drug delivery. Despite their potential, challenges such as immunogenicity, stability, heterogeneity, manufacturing scalability need to be addressed. Future research should focus on improving biocompatibility, advanced strategies, personalized medicine approaches, innovative techniques. Overcoming these will pave way for successful clinical translation nanodrugs, offering more effective safer treatments.

Язык: Английский

RGD-based self-assembling nanodrugs for improved tumor therapy DOI Creative Commons
Bin Wang, Dongmei Tang,

Jianqiao Cui

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Окт. 1, 2024

RGD-based self-assembling nanodrugs are a promising advancement in targeted cancer therapy, combining the specificity of RGD peptides with benefits nanotechnology. These enhance tumor targeting and cellular uptake while reducing off-target effects. facilitate self-assembly stable nanostructures, ensuring efficient drug delivery. Despite their potential, challenges such as immunogenicity, stability, heterogeneity, manufacturing scalability need to be addressed. Future research should focus on improving biocompatibility, advanced strategies, personalized medicine approaches, innovative techniques. Overcoming these will pave way for successful clinical translation nanodrugs, offering more effective safer treatments.

Язык: Английский

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