Light-Activated Nanofibers: Advances in Photo-Responsive Electrospun Polymer Technologies
Polymer-Plastics Technology and Materials,
Год журнала:
2024,
Номер
64(4), С. 397 - 438
Опубликована: Окт. 1, 2024
Язык: Английский
Stimuli‐Responsive Core‐Shell Electrospun Nanofibers for Drug Delivery: A Mini‐Review
Journal of Applied Polymer Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 31, 2025
ABSTRACT
Core‐shell
nanofibers
have
the
potential
to
surpass
traditional
monolithic
electrospun
in
drug
delivery,
due
their
ability
encapsulate
sensitive
therapeutics
within
core,
protect
them
from
degradation,
and
enable
controlled
release
profiles
through
shell.
When
designed
be
stimuli‐responsive,
these
evolve
“smart”
delivery
platforms
for
advanced
therapeutic
applications.
This
mini‐review
examines
recent
advancements
fabrication
applications
of
stimuli‐responsive
core‐shell
nanofibers.
Key
techniques,
such
as
coaxial
electrospinning,
single‐nozzle
electrospinning
using
water‐in‐oil
or
oil‐in‐water
emulsions
immiscible
blends
(e.g.,
polyethylene
oxide
chitosan;
polyvinylpyrrolidone
polyvinylidene),
needleless
post‐fabrication
coating
methods,
are
discussed
along
with
respective
advantages
limitations.
Additionally,
review
also
explores
how
can
engineered
respond
stimuli
like
near‐infrared
(NIR)
light,
ultrasound,
temperature,
pH
changes.
Representative
examples
illustrate
reduce
initial
burst
release,
on‐demand
chemodrug
implement
photothermal
therapy
against
cancer
cells.
At
end,
we
offer
perspectives
on
challenges,
opportunities,
new
directions
future
development.
Язык: Английский
Advanced 3D Materials for Corneal Stroma Regeneration: A Preclinical Progress
Journal of Materials Chemistry B,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Corneal
stromal
defects
cause
global
blindness
and
entail
unmet
solutions
beyond
transplants.
This
review
highlights
scaffolds,
biomaterials,
signaling
cues
in
corneal
stroma
engineering
to
advance
next-generation
vision
therapies.
Язык: Английский
RGD-based self-assembling nanodrugs for improved tumor therapy
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Окт. 1, 2024
RGD-based
self-assembling
nanodrugs
are
a
promising
advancement
in
targeted
cancer
therapy,
combining
the
specificity
of
RGD
peptides
with
benefits
nanotechnology.
These
enhance
tumor
targeting
and
cellular
uptake
while
reducing
off-target
effects.
facilitate
self-assembly
stable
nanostructures,
ensuring
efficient
drug
delivery.
Despite
their
potential,
challenges
such
as
immunogenicity,
stability,
heterogeneity,
manufacturing
scalability
need
to
be
addressed.
Future
research
should
focus
on
improving
biocompatibility,
advanced
strategies,
personalized
medicine
approaches,
innovative
techniques.
Overcoming
these
will
pave
way
for
successful
clinical
translation
nanodrugs,
offering
more
effective
safer
treatments.
Язык: Английский
Amorphous solid dispersion to facilitate the delivery of poorly water-soluble drugs: recent advances on novel preparation processes and technology coupling
Expert Opinion on Drug Delivery,
Год журнала:
2024,
Номер
unknown, С. 1 - 16
Опубликована: Ноя. 1, 2024
Introduction
Amorphous
solid
dispersion
(ASD)
technique
has
recently
been
used
as
an
effective
formulation
strategy
to
significantly
improve
the
bioavailability
of
insoluble
drugs.
The
main
industrialized
preparation
methods
for
ASDs
are
mainly
hot
melt
extrusion
and
spray
drying
techniques;
however,
they
face
limitations
being
unsuitable
heat-sensitive
materials
organic
reagent
residues,
respectively,
therefore
novel
processes
technology
coupling
developing
have
received
increasing
attention.
Язык: Английский