Medicina, Год журнала: 2025, Номер 61(4), С. 656 - 656

Опубликована: Апрель 2, 2025

Neoplastic disorders, particularly malignant carcinomas, are complex systemic diseases characterized by unregulated cellular proliferation, the invasion of adjacent tissues, and potential metastasis to distant bodily sites. Among diverse spectrum cancer subtypes, melanoma is a highly aggressive form cutaneous originating in melanocytes, pigment-producing cells resident skin. This malignancy distinguished its rapid uncontrolled growth, as well propensity for vital organs, thereby posing significant challenges therapeutic intervention prognostication. Early detection crucial optimizing patient outcomes, diagnosis at an advanced stage often yields poor prognosis limited treatment options. Diagnostic modalities encompass comprehensive clinical evaluations dermatologists; radiological imaging techniques such ultrasonography, magnetic resonance (MRI), computed tomography (CT) scans; excisional biopsies accurate histopathological assessment. Malignant typically treated with surgery remove tumor, followed immunotherapy enhance immune response, targeted therapy tumors specific genetic mutations, chemotherapy stages, radiation manage metastasis, other adjunct therapies. review presents properties possible effects against quercetin found literature explores, based on observed physicochemical biological activity, development topical formulation application. Quercetin naturally occurring flavonoid compound abundant various plant-based food sources, including apples, onions, berries, citrus fruits, has exhibited promising antiproliferative, antioxidant, anticancer properties. Its distinctive biochemical structure enables effectively neutralize reactive oxygen species modulate key carcinogenic pathways, rendering it candidate managing tumors, melanoma.

Язык: Английский