New Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) mixed-ligand complexes: stractural, DFT, biological, and molecular docking studies

Bulletin of the Chemical Society of Ethiopia, Год журнала: 2024, Номер 38(2), С. 397 - 416

Опубликована: Янв. 23, 2024

The primary objective of the current framework was to synthesize novel mononuclear 1:1:1 complexes involving FeLG, CoLG, NiLG, CuLG, and ZnLG, where ligand (L) is identified as 4-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)hydrazono]methylphenyl-4-methylbenzenesulfonate, glycine (G) serves co-ligand. Comprehensive characterization investigated achieved through various analytical techniques, including FTIR, UV-Vis spectroscopy, elemental analysis, mass spectra, magnetic susceptibility measurements, molar conductivity assessments, thermogravimetric analysis (TGA). determination stoichiometry performed employing ratio technique, revealing octahedral geometry inherent in isolated metal complexes. Employing a density functional theory (DFT) approach, molecular structures designated compounds were theoretically elevated, quantum chemical descriptors derived provide deeper insight into their electronic properties. Furthermore, inhibitory potential these against fungal strains pathogenic bacteria prevalent Arab environment evaluated using disc diffusion method, emphasizing role combating diseases affecting humans, animals, plants. Notably, exhibited superior antibacterial activity, evidenced by higher activity index. Molecular docking investigations conducted ascertain effects on 1FJ4 protein, with ZnLG emerging compound highest binding affinity. These results suggest promising candidacy antimicrobial agents, particularly context bacterial infections. KEY WORDS: Complexes, Antimicrobial, DFT, Schiff base, docking Bull. Chem. Soc. Ethiop. 2024, 38(2), 397-416. DOI: https://dx.doi.org/10.4314/bcse.v38i2.9

Язык: Английский

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Chitosan/aloe vera gel coatings infused with orange peel essential oils for fruits preservation

Current Research in Food Science, Год журнала: 2024, Номер 8, С. 100680 - 100680

Опубликована: Янв. 1, 2024

Continuous fruit waste poses significant environmental and economic challenges, necessitating innovative coating technologies. This research focuses on harnessing discarded orange peels to extract essential oil (OPEO), which is then integrated into a chitosan/aloe vera (CTS/AVG) matrix. The study comprehensively characterised the in terms of its physicochemical properties, antioxidant capacity, antimicrobial efficacy. investigation involved an analysis particle size distribution solutions, highlighting changes induced by incorporation peel (1 %, 2 % 3 v/w) (4:1 v/v) matrix, including reduction enhanced Brownian motion. quantifies 33.21 decrease water vapour transmission rate diffusion coefficient from 9.26 × 10-11 m

Язык: Английский

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Nutrient Profiling of Some Terrestrial Plant Leaves for Their Prospective Use as Nonconventional Ingredients in Carp Diets

Aquaculture Research, Год журнала: 2025, Номер 2025(1)

Опубликована: Янв. 1, 2025

The present study was performed to investigate the basic chemical composition and nutritional value of 10 terrestrial plant leaves (viz. Mangifera indica, Litchi chinensis, Artocarpus heterophyllus, Ziziphus mauritiana, Albizia lebbeck, Tamarindus Cicer arietinum, Bauhinia acuminata, Delonix regia Peltophorum pterocarpum ) abundant in tropical subtropical environments. leaf meals were evaluated comprehensively, encompassing proximate (% dry matter), amino acids, fatty antinutritional factors (ANFs), antioxidants antibacterial potential using established methodologies. crude protein (CP) content ranged from 10.92% 20.74% (w/w), with highest observed A . lebbeck leaves. lipid (CL) fibre (CF) contents varied between 1.23%–5.38% 13.73%–24.63%, respectively (w/w). protein‐to‐energy ratio (P/E) 32.32 60.70 mg/kcal, significantly higher ( p < 0.05) P/E A. compared other Dominant acids included palmitic acid (C16:0), oleic (C18:1n9c) linolenic (C18:3n3). Considerable amounts essential (EAAs) nonessential (NEAAs) recorded leaves, maximum quantities detected heterophyllus , respectively. Notably, substantial mineral elements also Z. mauritiana identified as a rich source iron (Fe), copper (Cu) manganese (Mn), while calcium (Ca), phosphorus (P) magnesium (Mg) levels Furthermore, aqueous extracts exhibited antioxidant potentials, activities for both T. indica Analyses ANFs indicated presence trypsin inhibitor (TI) (1.62–3.69 mg/g), tannin (21.25–61.25 phytic (1.74–5.42 cellulose (14.53%–21.37%) hemicellulose (5.48%–10.56%) conclusively proposes utilization leguminous plants, particularly B. acuminata P. nonconventional ingredients after eliminating or deactivating major ANFs. This information on nutrients less explored can be used optimize low‐cost carp diet formulation ensure economic profitability fish farmers region.

Язык: Английский

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Lithium Content and Its Nutritional Beneficence, Dietary Intake, and Impact on Human Health in Edibles from the Romanian Market

Foods, Год журнала: 2024, Номер 13(4), С. 592 - 592

Опубликована: Фев. 16, 2024

Lithium (Li) is present in human nutrition based on food intake, and several studies recommend it for treating mood disorders, even if the biological proprieties biochemical mechanisms represent basis its use as an essential element. The Li content was evaluated using inductively coupled plasma mass spectrometry technique (ICP-MS) 1071 beverage samples from Romanian market. results show that had a decreasing mean concentration follows: vegetables leafy > bulbous fructose leguminous egg whites root milk products yolks meats. Approximately quarter of all data each dataset category extreme values (range between third quartile maximum value), with only 10% below detection limit. Mean indicated higher red wine, white wines, beers, fruit juice lower ciders bottled waters. A particular interest addressed to plants teas coffee seeds, which showed narrow amounts Li. For both beverages, two similar matrices, including were found have significant differences, explains high variability uptake various matrices. 99.65% analyzed samples, estimated daily intake provisional subchronic chronic reference dose (2 µg/kgbw/day) adverse effects organs systems. Even so, risk occurs consuming (Li 13.47 mg/kg) solano 11.33 mg/kg). study’s findings indicate ingesting most beverages could be considered safe, future regarding content, nutritional aspects, cohort diseases must conducted.

Язык: Английский

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Advancements in fruit preservation technologies: Harnessing chitosan, aloe vera gel, and plant-based essential oils for coating applications

Applied Food Research, Год журнала: 2024, Номер 4(2), С. 100439 - 100439

Опубликована: Июнь 22, 2024

This work is centred on an eco-friendly method of preserving fruits via chitosan and aloe vera gel coating reinforced with plant-based essential oils. It analyzes the correlation physicochemical properties, structure, composition biological activity chitosan, oil. Extensive understanding this particular topic shows that edible coatings, specifically their composition, play important role in postharvest quality maintenance fruits. The research looks into binding mechanisms interaction modes such coatings gives evidence about effectiveness fresh produce, slowing down food spoilage implying overall nutritional value produce. article deals development sustainable process which fruit shelf-life are improved, resources made more efficient while generating as little waste possible. highlights putting wastes to bioactive oil production, promoting environmentally conscious well less costly approach processing. findings study therefore represent a very timely contribution existing practices future directions friendly processes preservation, may eventually usher innovative alternative conventional thinking packaging preservation.

Язык: Английский

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Chemical Composition Antioxidant and Anti-Inflammatory Activities of Myrtus communis L. Leaf Extract: Forecasting ADMET Profiling and Anti-Inflammatory Targets Using Molecular Docking Tools

Molecules, Год журнала: 2024, Номер 29(4), С. 849 - 849

Опубликована: Фев. 14, 2024

Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options human healthcare. In this study, we aimed systematically unravel the profile and antioxidant anti-inflammatory activities of myrtle methanolic extract (MMEx) using in vitro, vivo, silico approaches. High levels TPC (415.85 ± 15.52 mg GAE/g) TFC (285.80 1.64 QE/g) were observed. Mass spectrophotometry (GC-MS) analysis revealed presence 1,8-cineole (33.80%), α-pinene (10.06%), linalool (4.83%), p-dimethylaminobenzophenone (4.21%), thunbergol (4%), terpineol (3.60%), cis-geranyl acetate (3.25%), totarol (3.30%) major compounds. MMEx induced pronounced dose-dependent inhibition all assays, best activity was found with H

Язык: Английский

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A STEP FORWARD TO REVOLUTIONIZE THE EIMERIOSIS CONTROLLING STRATEGIES IN CATTLE BY USING TRADITIONAL MEDICATION

Experimental Parasitology, Год журнала: 2025, Номер unknown, С. 108926 - 108926

Опубликована: Март 1, 2025

Язык: Английский

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Making Cells “Greener:” Research Progress of Natural Green Plant Extracts in Perovskite Solar Cells

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Апрель 4, 2025

Abstract Perovskite solar cells (PSCs) have great potential as a third‐generation emerging photovoltaic technology. Nevertheless, the perovskite films prepared by conventional solution methods are plagued large number of defects, which not only serve nonradiative recombination centers, but also more susceptible to influence water/oxygen/light in environment, further degrading film quality. To address this challenge, additive engineering has been widely applied PSCs. This review summarizes research progress low‐cost, natural, environmentally friendly, and nontoxic plant extracts improving device performance. Specifically, advantages limitations different kinds PSCs, analysis each layer adjacent interface Furthermore, effects applications on PSCs discussed from four aspects, namely, regulating crystallinity crystals, stability, adjusting energy levels, innovative applications. Finally, prospects role development large‐scale industrialization.

Язык: Английский

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Polyphenols as Suitable Control for Obesity and Diabetes

The Open Biotechnology Journal, Год журнала: 2018, Номер 12(1), С. 219 - 228

Опубликована: Сен. 28, 2018

Modern life is characterized by physical inactivity and poor food choices, which often a prerequisite for unhealthy weight gain overweight/obesity. These factors unlock the emergence of number diseases including diabetes, cardiovascular problems, different types cancer, etc. The pursuit scientists to seek strategies prevent, relieve cure patient leads usage natural compounds potential beneficial effect. Polyphenols are large group naturally occurring secondary metabolites mainly found in plants beverages. presence these seems decrease manifestation miscellaneous disease-causing symptoms. purpose this review synthesize information about polyphenols their controlling obesity diabetes. considered as health-beneficial sources thus could be involved novel preventing diabetes complications.

Язык: Английский

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Botanical control of coccidiosis in ruminants

The Pakistan Journal of Agricultural Sciences, Год журнала: 2023, Номер 60(04), С. 473 - 485

Опубликована: Дек. 1, 2023

Coccidiosis is one of the major parasitic diseases infecting almost all ruminants, including cows, buffalo, sheep, and goats. caused by genus Eimeria, which are host-specific obligate intestinal parasites. These found over world cause infections leading to mortalities morbidities. usually treated ionophores synthetic chemicals various classes chemical drugs. drugs have been effective against coccidiosis but emerging issues anthelmintic resistance, public health concerns, consumer demand for organic products minimizing use these Vaccination also being used, vaccine failure high cost limit their use. Among alternatives, herbal medicines promising replacements because complex formulations, multiple modes action, easy availability, cost-effectiveness. Various plants, parts, formulations like preparations, active compounds in them searched control ruminant coccidiosis. Multiple groups botanical i.e., Flavonoids, alkaloids, tannins, terpenes, sulfur compounds, etc. proven be coccidiosis-causing agents. They can stages Eimeria directly indirectly antioxidant immunomodulatory actions. Further research needed determine most suitable preparations pharmacological interactions sustainable ruminants. This review highlights significance coccidiosis, used mechanisms reasons benefits compounds.

Язык: Английский

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