IOP Conference Series Earth and Environmental Science,
Год журнала:
2024,
Номер
1399(1), С. 012001 - 012001
Опубликована: Сен. 1, 2024
Abstract
Moringa
oleifera
leaves
of
different
ages
grown
in
Binh
Phuoc,
Vietnam
were
harvested
for
methanol
extraction,
total
polyphenol
content
(TPC)
and
biological
activity
determination.
Three
groups
age
collected
research
including
5-10
days-old
(L1),
25-30
(L2)
45-50
(L3).
The
TPC
determined
(mg
GAE/g
crude
extract)
leaf
methanolic
extract
(LME)
was
64.43
±
2.57;
47.75
3.11
24.8
4
1.72
L1,
L2,
L3
respectively.
Anti-bacterial
days
old
extracts
(100
mg/mL)
showed
the
significant
results
against
Escherichia
coli
(
15.67
1.58
mm)
,
Staphylococcus
aureus
12.67
1.76
compared
to
from
other
ages.
This
group
also
revealed
anticoagulant
with
longer
Prothrombin
time
(PT)
lasting
26.153
1.6(s).
As
a
result,
conducted
antibacterial
serum
formulation.
After
14
preservation
conditions,
preserved
cold
temperature
2-8°C
(NT1)
S.
resistant
(15.23
0.76
more
slightly
effective
than
one
room
30-32°C
(NT2)
as
11.17
0.62
mm,
which
initially
stated
significance
on
final
product
during
preservation.
Life,
Год журнала:
2025,
Номер
15(4), С. 583 - 583
Опубликована: Апрель 1, 2025
Background:
Moringa
oleifera
is
one
of
the
most
famous
plants
used
for
medicinal
purposes.
Its
leaf
extracts
have
antimicrobial
activity
and
antioxidant
activities,
reduce
swelling
in
ulcers.
Objectives:
The
present
article
aimed
to
determine
metabolic
profile
from
two
samples
originating
India
evaluate
vitro
ex
vivo
their
biological
activities.
Methods:
properties
(methanol,
50%
ethanol,
70%
ethanol)
were
studied
antimicrobial,
anti-inflammatory,
contractile
effects
determined
by
assaying
circularly
isolated
smooth
muscle
(SM)
strips
a
rat’s
stomach.
Results:
obtained
results
indicated
that
had
amino
acid
organic
content
approximately
twice
second
sample.
In
all
tests,
ethanol
extract
both
showed
better
(209
mM
TE
100
g−1
DPPH
method).
ethanolic
Sample
1
exhibited
strongest
activity,
inhibiting
Gram-positive
Bacillus
cereus,
subtilis,
Staphylococcus
aureus.
highest
anti-inflammatory
demonstrating
effect
than
reference
drug
diclofenac.
Finally,
pre-incubation
SM
preparations
with
significantly
enhanced
ACh-induced
response,
increasing
it
134%
111%,
respectively.
Conclusions:
findings
suggested
potential
applications
as
suitable
candidate
antioxidant,
antispasmodic
supplementation
alternative
pharmaceutical
nutraceutical
products.
Asian Journal of Research in Pharmaceutical Sciences,
Год журнала:
2025,
Номер
unknown, С. 87 - 91
Опубликована: Март 7, 2025
Moringa
oleifera,
a
tropical
plant,
has
been
extensively
studied
for
its
remarkable
nutritional
and
medicinal
properties.
This
comprehensive
review
examines
Moringa's
phytochemical
composition,
including
vitamins,
minerals,
bioactive
compounds.
We
analyze
pharmacological
effects,
antioxidant,
anti-inflammatory,
antimicrobial,
anticancer
activities.
Potential
applications
in
medicine,
water
treatment,
agriculture,
food
industries
are
discussed,
highlighting
versatility
potential
to
address
global
challenges.
Bioactive Compounds in Health and Disease - Online ISSN 2574-0334 Print ISSN 2769-2426,
Год журнала:
2024,
Номер
7(4), С. 185 - 198
Опубликована: Апрель 12, 2024
Background:
Moringa
oleifera
pods
are
the
main
constituent
in
typical
diets
throughout
Thailand.
Due
to
their
nutrients
and
phytochemicals,
moringa
have
potential
as
an
antioxidant
anti-inflammatory
agent.
Freeze
drying
is
a
widely
embraced
method
known
for
extending
shelf
life,
resulting
preserved
high-quality
products.
Objective:
This
study
aimed
investigate
physical
properties,
nutrients,
bioactive
compounds
of
freeze-dried
well
effects
on
lipopolysaccharide-induced
Raw
264.7
macrophages.
Methods:
were
ground.
The
powders
extracted
with
70%
ethanol
at
room
temperature
24
hr.
then
centrifuged
5000
rpm
25áµ’C.
supernatant-filtered
extracts
collected
determine
compound
contents
properties.
Results:
results
illustrated
that
pod
extract
had
including
genistein
synthetic,
trans-ferulic
acid,
p-Coumaric,
myricetin,
gallic
syringic
which
demonstrated
activity.
In
terms
effects,
50-200
µg/ml
inhibited
pro-inflammatory
mediators
NO
production
IL-6
TNF-α
levels
LPS-induced
These
indicate
properties
make
them
promising
new
raw
material
functional
product
development.
Keywords:
Anti-inflammation,
oleifera,
acid.
Frontiers in Veterinary Science,
Год журнала:
2024,
Номер
11
Опубликована: Апрель 10, 2024
Chlorpyrifos
(CPF)
is
one
of
the
most
commonly
used
organophosphosphate-based
(OP)
insecticides.
Its
wide
use
has
led
to
higher
morbidity
and
mortality,
especially
in
developing
countries.
Moringa
seed
extracts
(MSE)
have
shown
neuroprotective
activity,
antioxidant,
anti-inflammatory,
antibacterial
features.
The
literature
lacks
data
investigating
role
MSE
against
CPF-induced
cerebral
ocular
toxicity
mice.
Therefore,
we
aim
investigate
this
concern.
A
total
40
mature
male
Wistar
Albino
mice
were
randomly
distributed
five
groups.
Initially,
they
underwent
a
one-week
adaptation
period,
followed
by
treatment
regimen.
groups
included
control
group
that
received
saline,
100
mg/kg,
CPF
12
CPF-MSE
50
mg/kg.
After
phase,
analyses
conducted
on
serum,
ocular,
tissues.
MSE100
CPF-MSE100
normalized
pro-inflammatory
markers
(interleukin-1β
(IL-1β),
interleukin-6
(IL-6),
tumor
necrosis
factor-alpha
(TNF-α))
AChE
serum
levels.
CPF-MSE50
significantly
enhanced
these
levels
compared
CPF;
however,
it
showed
control.
Moreover,
tissue
analysis
significant
decrease
oxidative
stress
(malondialdehyde
(MDA)
nitric
oxide
(NO))
an
increase
antioxidant
(glutathione
(GSH),
glutathione
peroxidase
(GSH-PX)),
superoxide
dismutase
(SOD),
catalase
(CAT)
treated
CPF.
Importantly,
significance
effects
was
found
be
dose-dependent,
particularly
evident
group.
We
conclude
promising
therapeutic
effect
tissues
CPF-intoxicated
mice,
providing
potential
solution
for
OP
public
health
issues.
IntechOpen eBooks,
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 10, 2024
The
antimicrobial
capabilities
of
Moringa
oleifera
have
garnered
significant
scientific
attention
due
to
its
rich
array
bioactive
compounds.
This
chapter
provides
a
comprehensive
examination
the
activities
exhibited
by
various
components
plant,
including
seeds,
leaves,
roots,
fruits,
and
flowers.
Notably,
containing
potent
4-(alpha-L-rhamanosyloxy)
benzyl
isothiocyanates,
demonstrate
strong
effects
against
broad
spectrum
bacterial
strains,
Bacillus
cereus
Staphylococcus
aureus,
as
well
fungi.
Furthermore,
lectins
within
seeds
interact
with
membranes,
impeding
growth
viability.
leaves
exhibit
pronounced
actions
both
Gram-positive
Gram-negative
bacteria,
facilitated
phenolic
compounds
that
disrupt
essential
functions.
Similarly,
roots
antibacterial
antifungal
properties,
attributed
like
N-benzylethyl
thioformate,
presenting
promising
alternatives
conventional
antibiotics.
Additionally,
fruits
flowers
display
efficacy,
such
phenols
flavonoids
demonstrating
activity
common
pathogens
Candida
albicans
Escherichia
coli.
in-depth
analysis
underscores
multifaceted
potential
oleifera,
highlighting
pathways
for
further
research
development
novel
agents
nutraceuticals.
