International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
26(1), С. 94 - 94
Опубликована: Дек. 26, 2024
Green
chemistry
focuses
on
reducing
the
environmental
impacts
of
chemicals
through
sustainable
practices.
Traditional
methods
for
extracting
bioactive
compounds
from
Eucalyptus
marginata
leaves,
such
as
hydro-distillation
and
organic
solvent
extraction,
have
limitations,
including
long
extraction
times,
high
energy
consumption,
potential
toxic
residues.
This
study
explored
use
supercritical
fluid
(SFE),
pressurized
liquid
(PLE),
gas-expanded
(GXL)
processes
to
improve
efficiency
selectivity.
These
techniques
were
combined
in
a
single
mixture
design,
where
CO2
was
used
experiments
carried
out
under
SFE,
while
water
ethanol
PLE
GXL
by
varying
concentration
solvents
cover
all
possibilities.
The
neuroprotective
activity
extracts
evaluated
measuring
their
antioxidant,
anti-inflammatory,
acetylcholinesterase
inhibition
properties.
optimization
resulted
novel
with
an
optimal
ternary
27%
CO2,
55%
ethanol,
18%
water,
degree
desirability
(R2
=
88.59%).
Chromatographic
analysis
GC-MS
HPLC-ESI-MS/MS
identified
over
49
metabolites.
designed
process
offers
promising
approach
producing
phenolic-rich
plant
industrial
applications.
Polymers,
Год журнала:
2024,
Номер
16(23), С. 3368 - 3368
Опубликована: Ноя. 29, 2024
The
integration
of
machine
learning
(ML)
into
material
manufacturing
has
driven
advancements
in
optimizing
biopolymer
production
processes.
ML
techniques,
applied
across
various
stages
production,
enable
the
analysis
complex
data
generated
throughout
identifying
patterns
and
insights
not
easily
observed
through
traditional
methods.
As
sustainable
alternatives
to
petrochemical-based
plastics,
biopolymers
present
unique
challenges
due
their
reliance
on
variable
bio-based
feedstocks
processing
conditions.
This
review
systematically
summarizes
current
applications
techniques
aiming
provide
a
comprehensive
reference
for
future
research
while
highlighting
potential
enhance
efficiency,
reduce
costs,
improve
product
quality.
also
shows
role
algorithms,
including
supervised,
unsupervised,
deep
Separations,
Год журнала:
2025,
Номер
12(1), С. 8 - 8
Опубликована: Янв. 3, 2025
This
research
paper
investigates
the
phytochemical
profile,
antioxidant
activity,
antidiabetic
potential,
and
antibacterial
activity
of
Myrtus
communis
berries.
Two
extraction
methods
were
employed
to
obtain
extracts:
solid–liquid
ultrasound-assisted
(UAE)
supercritical
fluid
(SFE).
The
extracts
characterized
using
spectrophotometric
Reversed-Phase
High-Performance
Liquid
Chromatography
(RP-HPLC).
UAE
extract
exhibited
higher
total
flavonoid
anthocyanin
content,
while
SFE
prevailed
in
phenolic
content
DPPH
radical
screening
assay.
RP-HPLC
characterization
identified
quantified
several
polyphenolic
compounds.
In
extract,
epigallocatechin
was
found
a
concentration
2656.24
±
28.15
µg/g
dry
weight
(DW).
cafestol
compound
with
highest
at
level
29.65
0.03
DW.
Both
contained
compounds,
including
cyanidin
3-O-glucoside
chloride,
cyanidin-3-O-rutinoside
malvidin-3-O-glucoside
pelargonidin
peonidin
peonidin-3-O-rutinoside
chloride.
potential
evaluated
vitro
by
measuring
inhibition
α-amylase
from
porcine
pancreas
(type
I-A).
results
highlighted
ability
myrtle
berry
inhibit
enzymatic
suggesting
its
as
an
alternative
for
controlling
postprandial
hyperglycemia.
showed
lowest
IC50
value
among
two
extracts,
average
8.37
0.52
µg/mL
assessed
against
Bacillus
spp.,
Escherichia
coli,
Staphylococcus
aureus
disk
diffusion
method.
similar
tested
bacterial
strains.
support
further
investigation
berries
ingredient
functional
food
formulation,
particularly
due
antioxidant,
antidiabetic,
properties.
Processes,
Год журнала:
2025,
Номер
13(2), С. 300 - 300
Опубликована: Янв. 22, 2025
The
extraction
of
bioactive
compounds,
such
as
flavonoids
and
coumarins,
from
natural
sources
has
gained
significant
attention
due
to
their
potential
health
benefits.
This
review
aims
explore
the
application
high-pressure
processes,
particularly
supercritical
fluid
(SFE)
pressurized
liquid
(PLE),
for
obtaining
coumarins
flower
seeds.
These
techniques
offer
a
greener,
more
efficient
alternative
conventional
methods,
minimizing
use
harmful
solvents
improving
yield
purity
target
compounds.
Flower
seeds,
rich
source
molecules,
are
an
underutilized
reservoir
these
valuable
For
example,
seeds
plants
Calendula
officinalis
(calendula)
Helianthus
annuus
(sunflower)
in
coumarins.
proposed
will
examine
influence
parameters—such
temperature,
pressure,
solvent
choice,
time—on
quality
provide
comprehensive
understanding
methods
optimize
protocols
efficient,
sustainable
Plants,
Год журнала:
2025,
Номер
14(7), С. 1071 - 1071
Опубликована: Апрель 1, 2025
This
study
aimed
to
compare
the
efficiency
of
different
green
extraction
methods
for
obtaining
bioactive
compounds
from
roots
Rheum
cordatum
Losinsk
and
evaluate
their
antioxidant
antimicrobial
properties.
The
presence
some
important
phytochemicals
in
extracts
obtained
using
ultrasound-assisted
(UAE),
subcritical
ethanol
(Sbc-EtOH),
supercritical
CO2
(ScCO2)
was
determined
by
LC-MS/MS,
properties
were
examined
against
Staphylococcus
aureus,
Enterococcus
faecalis,
Pseudomonas
aeruginosa,
Escherichia
coli.
goal
determine
optimal
conditions
that
maximize
yield
while
preserving
biological
Different
pressures
(100
bar
400
bar)
tested
UAE
extraction,
solvents
times
Sbc-EtOH
ScCO2
extraction.
Most
53
phenolic
have
been
extracted
method,
either
exclusively
or
highest
amounts.
It
has
observed
more
higher
amounts
at
lower
pressure.
activity
exhibited
extracts.
Additionally,
ScCO2-100
extract
100
showed
strong
activity,
with
a
minimum
inhibitory
concentration
(MIC)
ranging
31.25
250
μg/mL.
Gallic
acid,
epicatechin
gallate,
epigallocatechin
catechin
found
molecular
docking
studies
1QWZ,
2ANQ,
3H77,
6QXS
proteins
revealed
scores
-6.127,
-9.479,
-5.836,
-7.067
kcal/mol,
respectively.
Processes,
Год журнала:
2025,
Номер
13(4), С. 1124 - 1124
Опубликована: Апрель 9, 2025
In
general,
there
are
three
methods
for
extracting
oil
from
various
sources:
mechanical,
solvent,
and
pre-press-solvent.
Each
of
these
has
its
own
advantages
disadvantages,
with
extraction
efficiency
depending
on
key
factors
such
as
the
technique,
properties
plant
component
matrix,
solvent
used.
Factors
like
temperature,
pressure,
time
also
play
a
role.
Researchers
have
consistently
sought
to
replace
or
complement
reduce
residual
in
products.
This
study
introduces
new
that
gained
attention
recent
years,
including
microwave,
pulsed
electric
field,
ultrasound,
supercritical
fluid,
enzymatic,
ohmic,
combined
enhance
efficiency.
The
research
demonstrates
increase
bioactive
compound
sources,
resulting
improved
quality.
Most
time,
offering
researchers
industrialists
variety
options
their
needs.
However,
notes
contradictions
results,
varying
acidity
levels
oil,
which
may
be
attributed
raw
materials
conditions.
end,
it
was
determined
enzyme
can
used
industrially
extract
olives,
while
fluid
certain
seeds.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(8), С. 3834 - 3834
Опубликована: Апрель 18, 2025
The
cultivation
and
processing
of
fruits
generate
a
wide
range
by-products
(e.g.,
pulp,
seeds,
pomace,
leaves,
stems),
which
are
often
underutilized
despite
being
rich
sources
phenolic
compounds
with
well-documented
bioactive
properties.
potential
these
has
attracted
significant
interest
from
both
the
pharmaceutical
food
sectors,
offering
opportunities
for
their
use
in
functional
foods,
dietary
supplements,
natural
medicines,
additives.
Among
these,
acids
have
shown
promising
modulating
risk
factors
associated
metabolic
syndrome
(MetS),
condition
encompassing
hypertension,
dyslipidemia,
hyperglycemia,
abdominal
obesity,
contributing
significantly
to
cardiovascular
disease.
Given
global
burden
MetS
need
novel
preventive
strategies,
numerous
studies
investigated
bioactivity
derived
fruit
by-products.
In
this
review,
we
critically
examine
recent
regarding
acid
composition
fruit-derived
biological
activity
relation
MetS-related
factors.
This
work
aims
synthesize
current
findings,
highlight
prevailing
research
trends,
identify
existing
gaps
literature
inform
future
promote
sustainable
prevention
management
MetS.
