Journal of environmental chemical engineering, Год журнала: 2025, Номер unknown, С. 115779 - 115779
Опубликована: Фев. 1, 2025
Язык: Английский
The Science of The Total Environment, Год журнала: 2023, Номер 904, С. 167243 - 167243
Опубликована: Сен. 22, 2023
Язык: Английский
Процитировано
44
Environmental Advances, Год журнала: 2023, Номер 13, С. 100409 - 100409
Опубликована: Авг. 13, 2023
The rapid development and spread of antimicrobial resistance in the post-antibiotic era has become a global concern. Recent evidence indicates that, at present, antibiotic is evolving an alarming rate as defense mechanism against anthropogenic chemical stresses. Mechanistically, bacterial to antibiotics involves reduced permeability, active efflux, modification target site, and/or inactivation molecule encoded by genes (ARGs) that are majorly carried mobile genetic elements (MGEs). Horizontal gene transfer (HGT) facilitates inter intra-species dissemination MGEs drives ARGs, which leads environmental resistome. Clinical severe consequences on health economy if left unchecked. For routine monitoring resistance, traditional culture-based methods, reliable polymerase chain reaction (PCR)-based addition recent high throughput next-generation sequencing (NGS)-based often used. present work critically reviews mechanisms for evolution tools monitor emergence such efforts management growing threat spearheaded World Health Organization (WHO) collaboration with developed developing countries alike. highlights policies national levels implement stewardship programs, awareness campaigns, prevention practices, healthcare guidelines promote ensure judicious prescription antimicrobials containment resistance.
Язык: Английский
Процитировано
29
Polymers, Год журнала: 2024, Номер 16(3), С. 410 - 410
Опубликована: Фев. 1, 2024
The total rate of plastic production is anticipated to surpass 1.1 billion tons per year by 2050. Plastic waste non-biodegradable and accumulates in natural ecosystems. In 2020, the amount was estimated be 367 million metric tons, leading unmanageable disposal environmental pollution issues. Plastics are produced from petroleum gases. Given limited fossil fuel reserves need circumvent problems, focus has shifted biodegradable biopolymers, such as polyhydroxyalkanoates (PHAs), polylactic acid, polycaprolactone. PHAs gaining importance because diverse bacteria can produce them intracellular inclusion bodies using biowastes feed. A critical component PHA downstream processing procedures recovery purification. this review, different bioengineering approaches targeted at modifying cell morphology synchronizing lysis with biosynthetic cycle presented for product separation extraction. Complementing genetic engineering strategies conventional processes, these expected sustainably.
Язык: Английский
Процитировано
11
Environmental Research, Год журнала: 2025, Номер unknown, С. 120895 - 120895
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
2
Polymers, Год журнала: 2024, Номер 16(21), С. 3015 - 3015
Опубликована: Окт. 28, 2024
Nowadays, plastic contamination worldwide is a concerning reality that can be addressed with appropriate society education as well looking for innovative polymeric alternatives based on the reuse of waste and recycling circular economy point view, thus taking into consideration future world without quite impossible to conceive. In this regard, in review, we focus sustainable materials, biodegradable bio-based polymers, additives, micro/nanoparticles used obtain new environmentally friendly polymeric-based materials. Although polymers possess poorer overall properties than traditional ones, they have gained huge interest many industrial sectors due their inherent biodegradability natural environments. Therefore, several strategies been proposed improve extend applications. Blending strategies, development composites nanocomposites, shown promising perspectives improving performances, emphasizing biopolymeric blend formulations micro nanoparticles produce fully The Review also summarizes recent developments blends, composites, nanocomposite plasticization, particular naturally derived plasticizers chemical modifications increase compatibility matrices. current state art most important reviewed, mainly focusing synthesis processing methods scalable sector, such melt solution blending approaches like melt-extrusion, injection molding, film forming electrospinning, among others, neglecting degradation processes.
Язык: Английский
Процитировано
9
Deleted Journal, Год журнала: 2024, Номер unknown
Опубликована: Март 11, 2024
Abstract Poly(hydroxyalkanoates) (PHAs) are a class of sustainable, bio-based thermoplastic polymers with attractive physiochemical properties, including non-toxicity, biocompatibility, elastomeric behavior by design, and piezoelectric characteristics. In the ongoing effort to reduce plastics waste, PHAs can play substantial role due their inherent biodegradability free microplastics, customizable versatile applications. This includes tremendous potential in broad range biomedical Biomass-based materials have recently gained great interest health sector, given vast amount interdisciplinary research bioengineering medicine. Implantable biomaterials should not elicit any negative response at implantation site, which differentiates them from general-purpose polymers. do induce thrombosis or antigenic even after being contact blood human body during long-term use. The biocompatibility is also key factor rapid growth proliferation tissues onto within these when served as tissue engineering scaffolds. By application, field was estimated be second-largest market share for PHAs, terms volume, 2022. While PHA-based bring forth opportunities, they present challenges that limited widespread use greater share. A better understanding properties biodegradation rates, production challenges, need cost-effective strategies some hurdles addressed. review paper provides an overview commonly used PHA homopolymers copolymers fields packaging industries. introduction manuscript presents concept bioplastics environmental significance, highlighting urgent alternatives conventional fossil-based plastics. next sections briefly cover synthesis, well homopolymer copolymer formulations, followed application field. Current opportunities together insight into future gathered published studies, been brought concluding section this paper.
Язык: Английский
Процитировано
8
Microorganisms, Год журнала: 2024, Номер 12(10), С. 2028 - 2028
Опубликована: Окт. 8, 2024
The search for alternatives to petrochemical plastics has intensified, with increasing attention being directed toward bio-based polymers (bioplastics), which are considered healthier and more environmentally friendly options. In this review, a comprehensive overview of polyhydroxyalkanoates (PHAs) is provided, including their characterization, applications, the mechanisms underlying biosynthesis. PHAs natural polyesters produced by wide range prokaryotic some eukaryotic organisms, positioning them as significant widely studied type bioplastic. Various strategies production from agroindustrial waste, such cacao shells, cheese whey, wine, wood, beet molasses, reviewed, emphasizing potential sustainable feedstocks. Industrial processes PHAs, complexities associated extraction purification, also examined. Although use waste materials offers promise in reducing costs environmental impact, challenges remain optimizing these enhance efficiency cost-effectiveness. need continued research development improve sustainability economic viability PHA emphasized, viable eco-friendly alternative conventional petroleum-based plastics.
Язык: Английский
Процитировано
8
Bioengineered, Год журнала: 2025, Номер 16(1)
Опубликована: Янв. 30, 2025
Polyhydroxyalkanoates (PHA) are bioplastics produced by few bacteria as intracellular lipid inclusions under excess carbon source and nutrient-deprived conditions. These polymers biodegradable resemble petroleum-based plastics. The rising environmental concerns have increased the demand for PHA, but low yield in wild-type bacterial strains limits large-scale production. An improvement PHA production can be achieved genetically engineering removing competitive pathways that divert metabolites away from biosynthesis, cloning strong promotors to overexpress genes involved biosynthesis constructing non-native metabolic feed desired monomers were obtained elimination of biosynthetic pathway. chain length degradation specific-gene deletion β-oxidation pathway resulted accumulation having high length. A controlled polymer was novel deleting native genome non-PHA producers. present review attempts showcase genetic modification approaches conducted so far enhance with a special focus on gene various bacteria.
Язык: Английский
Процитировано
1
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1
Polymers, Год журнала: 2024, Номер 16(15), С. 2227 - 2227
Опубликована: Авг. 5, 2024
Biopolymers are highly desirable alternatives to petrochemical-based plastics owing their biodegradable nature. The production of bioplastics, such as polyhydroxyalkanoates (PHAs), has been widely reported using various bacterial cultures with substrates ranging from pure biowaste-derived sugars. However, large-scale and economic feasibility major limiting factors. Now, algal biomass for PHA offers a potential solution these challenges significant environmental benefit. Algae, unique ability utilize carbon dioxide greenhouse gas (GHG) wastewater feed growth, can produce value-added products in the process and, thereby, play crucial role promoting sustainability. sugar recovery efficiency is variable depending on pretreatment procedures due inherent compositional variability among cell walls. Additionally, yields, composition, properties synthesized vary significantly microbial producers algal-derived Therefore, microalgal pretreatments synthesis copolymers still require considerable investigation develop an efficient commercial-scale process. This review provides overview discusses strategies enhance its properties, focusing managing GHGs sustainable future.
Язык: Английский
Процитировано
6