Avicenna Journal of Clinical Microbiology and Infection,
Год журнала:
2024,
Номер
11(1), С. 42 - 50
Опубликована: Март 30, 2024
Background:
Various
forms
of
microorganisms
have
developed
multiple
resistances
against
the
effects
applied
antibacterial
agents
controlling
them.
Hence,
there
is
a
need
to
formulate
potent
antimicrobial
from
natural
sources
eliminate
them
environment.
The
aim
this
study
was
investigate
potency
chitosan
conjugated
with
some
medicinal
plants
recalcitrant
and
overcome
problem
antibiotic
resistance.
Methods:
In
study,
synergistic
derived
snail
shells
were
explored
in
conjunction
eight
plant
sources,
including
Ocimum
gratissimum,
Croton
zambesicus,
Phyllanthus
niruri,
Aloe
barbadensis,
Moringa
oleifera,
Andrographis
paniculate,
Curcuma
longa.
investigation
focused
on
properties
these
combinations,
aiming
at
enhancing
efficacy
pharmaceutical
products
antibiotic-resistant
strains.
Four
samples
analyzed
regard.
Sample
A
consisted
0.5
g
sulphur
nanoparticles
(SNPs)
chitosan,
B
contained
1
SNPs
shrimp
dissolved
1%
acetic
acid.
addition,
C
involved
acid,
D
utilized
All
demonstrated
varied
potentials.
Results:
Notably,
B,
which
as
nanocarriers
for
SNPs,
exhibited
significant
activity,
zones
inhibition
measuring
up
35
mm
37
multidrug-resistant
strains
Staphylococcus
sp.
(coagulase-negative),
Klebsiella
oxytoca,
Escherichia
coli,
respectively.
Additionally,
promising
observed
organisms
such
Pseudomonas
aeruginosa,
ornithinolytica,
E.
zone
sizes
reaching
20
mm,
23
25
Iron
oxide
NPs
(Fe3
O4
)
silica-coated
iron
displayed
lower
activity
levels,
except
100
mg/mL
concentration,
where
they
represented
certain
AKR
18
-
Enterobacter
agglomerans,
OKI
10
Acinetobacter
haemolyticus,
T30
–
K.
oxytoca.
Conclusion:
findings
offer
valuable
insights
into
management
infectious
disease
treatment
challenging
pathogens
healthcare
systems,
providing
potential
roadmap
combating
resistance
improving
therapeutic
strategies.
Micromachines,
Год журнала:
2023,
Номер
14(9), С. 1786 - 1786
Опубликована: Сен. 18, 2023
Exploring
bio-inspired
nanomaterials
(BINMs)
and
incorporating
them
into
micro/nanodevices
represent
a
significant
development
in
biomedical
applications.
Nanomaterials,
engineered
to
imitate
biological
structures
processes,
exhibit
distinctive
attributes
such
as
exceptional
biocompatibility,
multifunctionality,
unparalleled
versatility.
The
utilization
of
BINMs
demonstrates
potential
diverse
domains
micro/nanodevices,
encompassing
biosensors,
targeted
drug
delivery
systems,
advanced
tissue
engineering
constructs.
This
article
thoroughly
examines
the
various
BINMs,
including
those
originating
from
proteins,
DNA,
biomimetic
polymers.
Significant
attention
is
directed
toward
these
entities
subsequent
ramifications
that
arise.
review
explores
biomimicry’s
structure–function
correlations.
Synthesis
mosaics
include
bioprocesses,
biomolecules,
natural
structures.
These
nanomaterials’
interfaces
use
functionalization
geometric
adaptations,
transforming
delivery,
nanobiosensing,
organ-on-chip
cancer-on-chip
models,
wound
healing
dressing
mats,
antimicrobial
surfaces.
It
provides
an
in-depth
analysis
existing
challenges
proposes
prospective
strategies
improve
efficiency,
performance,
reliability
devices.
Furthermore,
this
study
offers
forward-thinking
viewpoint
highlighting
avenues
for
future
exploration
advancement.
objective
effectively
utilize
maximize
application
progression
thereby
propelling
rapidly
developing
field
its
promising
future.
Marine Drugs,
Год журнала:
2024,
Номер
22(4), С. 153 - 153
Опубликована: Март 28, 2024
Shrimp
processing
generates
substantial
waste,
which
is
rich
in
valuable
components
such
as
polysaccharides,
proteins,
carotenoids,
and
fatty
acids.
This
review
provides
a
comprehensive
overview
of
the
valorization
shrimp
mainly
shells,
focusing
on
extraction
methods,
bioactivities,
potential
applications
these
bioactive
compounds.
Various
techniques,
including
chemical
extraction,
microbial
fermentation,
enzyme-assisted
microwave-assisted
ultrasound-assisted
pressurized
techniques
are
discussed,
highlighting
their
efficacy
isolating
acids
from
waste.
Additionally,
bioactivities
associated
with
compounds,
antioxidant,
antimicrobial,
anti-inflammatory,
antitumor
properties,
among
others,
elucidated,
underscoring
pharmaceutical,
nutraceutical,
cosmeceutical
applications.
Furthermore,
explores
current
utilization
avenues
for
emphasizing
importance
sustainable
resource
management
circular
economy
principles
maximizing
value
Overall,
this
paper
aims
to
provide
insights
into
multifaceted
aspects
waste
valorization,
offering
information
researchers,
industries,
policymakers
interested
waste-management
strategies.
Abstract
Growing
concerns
about
the
harmful
impact
of
synthetic
polymers
on
environment
and
living
organisms
have
shifted
attention
towards
biopolymers
which
are
environment‐friendly
biocompatible.
Biopolymers
represent
attractive
sustainable
biodegradable
alternatives
for
replacing
commercial
polymers.
Chitosan
is
one
most
prevalent
available
Earth.
an
alkaline
cationic
polymer,
deacetylated
form
chitin.
possesses
excellent
physicochemical
properties
such
as
biocompatibility,
biodegradability,
nontoxic,
nonallergenic,
biologically
active
molecules.
During
recent
years,
there
has
been
a
surge
in
demand
chitosan
various
fields,
however,
due
to
poor
water
solubility
mechanical
properties,
applications
limited
some
extent.
Strong
inter
intramolecular
hydrogen
bonds
matrix
make
it
highly
crystalline,
reducing
its
solubility.
Chemical
modification
by
technologies
reported
improve
other
characteristics,
expanding
application
areas.
Details
chemical
reactions
involved
focused
this
paper.
The
role
chitin
deacetylase
enzyme
discussed.
This
review
aims
provide
insight
into
developments
functionalization,
development
derivatives
applications.
Journal of Composites Science,
Год журнала:
2024,
Номер
8(3), С. 114 - 114
Опубликована: Март 21, 2024
Food
packaging
plays
an
imperative
role
in
the
food
processing
sector
by
safeguarding
foods
from
their
point
of
harvesting
until
moment
consumption.
In
recent
years,
biopolymers
have
attracted
attention
scientific
community
as
alternative
to
conventional
materials.
Among
available
biopolymer
sources,
a
lot
focus
has
been
on
polysaccharides
due
superior
barrier
properties
against
gases,
oils,
and
odors
versatility.
Moreover,
there
is
also
growing
interest
aliphatic
polyester
potential
replacement
for
petrochemical-based
synthetic
plastics.
Both
polyesters
gained
popularity
sustainable
unique
characteristics,
including
low
cost,
availability,
biodegradability,
gas
moisture
properties,
film-forming
capabilities,
excellent
heat
resistance,
ability
be
processed
into
films,
trays,
coatings.
This
review
highlights
structural
features,
advancements
several
vital
polysaccharides,
namely,
starch,
chitosan,
cellulose,
alginate,
pectin,
carrageenan,
polyesters,
polylactic
acid
(PLA)
polyhydroxybutyrate
(PHB)
developing
materials,
applications
industry.
Conventional
future
perspectives
biopolymer-based
are
comprehensively
covered
this
review.
Zeitschrift für Naturforschung C,
Год журнала:
2024,
Номер
79(5-6), С. 107 - 124
Опубликована: Май 1, 2024
Chitosan
(CT),
a
natural,
cationic,
chemically
stable
molecule,
biocompatible,
biodegradable,
nontoxic,
polysaccharide
derived
from
the
deacetylation
of
chitin,
has
very
uniquely
surfaced
as
material
promise
for
drug
delivery
and
biomedical
applications.
For
oral,
ocular,
cutaneous,
pulmonary,
nose-to-brain
routes,
CT-coated
nanoparticles
(CTCNPs)
have
numerous
advantages,
consisting
improved
controlled
release,
physicochemical
stability,
cell
tissue
interactions,
increased
bioavailability
efficacy
active
ingredient.
CTCNPs
broad
range
therapeutic
properties
including
anticancer,
antiviral,
antifungal,
anti-inflammatory,
antibacterial
properties,
treating
neurological
disorders,
other
diseases.
This
led
to
substantial
research
into
many
potential
uses
CT
vehicle.
also
been
employed
in
wide
processes,
bone
cartilage
regeneration,
ocular
periodontal
heart
wound
healing.
Additionally,
used
cosmeceutical,
bioimaging,
immunization,
gene
transfer
exhibits
number
biological
activities,
which
are
basis
its
remarkable
use
vehicle,
these
activities
covered
detail
this
article.
The
alterations
applied
obtain
necessary
described.
Current Nanomedicine,
Год журнала:
2023,
Номер
14(1), С. 13 - 27
Опубликована: Дек. 27, 2023
Abstract:
Age-related
macular
degeneration
(AMD)
is
a
leading
cause
of
permanent
blindness
globally.
Due
to
the
various
obstacles,
highly
invasive
intravitreal
(IVT)
injections
are
prima-ry
method
used
deliver
medications
tissues
posterior
eye.
An
utmost
patient-friendly
topical
ocular
delivery
approach
has
been
extensively
researched
in
recent
years.
Muco-adhesive
compositions
extend
precorneal
residence
time
while
reducing
clearance.
They
increase
likelihood
adhesion
corneal
and
conjunctival
surfaces
and,
as
result,
al-low
for
enhanced
eye
segment.
its
remarkable
mucoadhesive
characteristics,
chitosan
(CS)
undergone
most
extensive
research
any
polymer.
Drug
front
back
still
difficult.
The
pharmaceutical
in-dustry
shown
greater
interest
drug
systems
(DDSs)
based
on
nanotechnology
(NT)
years,
particularly
those
made
from
natural
polymers
like
chitosan,
alginate,
etc.
Be-cause
their
incredible
adaptability,
higher
biological
effects,
favourable
physicochemical
properties,
CS-oriented
nanomaterials
(NMs)
explored
by
researchers
prospective
nanocar-riers.
CS
right
substrates
develop
products,
such
hydrogels,
nanopar-ticles
(NP),
microparticles,
nanofibers,
whether
alone
or
composite
form.
CS-based
nanocarriers
medicine,
peptides,
growth
factors,
vaccines,
genetic
materials
regulated
targeted
This
review
highlights
current
developments
challenges
chi-tosan-mediated
nano
therapies
associated
with
AMD.
Nanomaterials,
Год журнала:
2024,
Номер
14(4), С. 351 - 351
Опубликована: Фев. 13, 2024
This
scientific
investigation
emphasizes
the
essential
integration
of
nature’s
influence
in
crafting
multifunctional
surfaces
with
bio-inspired
designs
for
enhanced
functionality
and
environmental
advantages.
The
study
introduces
an
innovative
approach,
merging
color
decoration,
humidity
sensing,
antiviral
properties
into
a
unified
surface
using
chitosan,
organo-biological
polymer,
to
create
cost-effective
multilayered
films
through
sol-gel
deposition
UV
photoinduced
metal
nanoparticles.
resulting
chitosan
showcase
diverse
structural
colors
demonstrate
significant
efficiency,
50%
85%
virus
inhibition
rate
within
rapid
20
min
reaction,
validated
fluorescence
cell
expression
real-time
qPCR
(polymerase
chain
reaction)
assays.
Silver-deposited
further
enhance
activity,
achieving
remarkable
91%
95%
independent
These
exhibit
humidity-responsive
modifications
across
25–90%
relative
range,
enabling
monitoring
simulation
studies.
proposed
three-in-one
functional
can
have
versatile
applications
medicine,
air
conditioning,
food
industry.
It
serve
as
sensor
indoor
outdoor
surfaces,
find
use
biomedical
devices
continuous
monitoring,
offer
protection
frequently
handled
tools.
customizable
visual
appeal,
making
it
comprehensive
solution
applications.
Molecules,
Год журнала:
2025,
Номер
30(3), С. 455 - 455
Опубликована: Янв. 21, 2025
The
escalating
presence
of
antibiotic-resistant
bacteria
(ARB)
in
food
systems
presents
a
pressing
challenge,
particularly
preventing
contamination
and
ensuring
safety.
Traditional
sanitation
methods,
such
as
cooking
chemical
disinfectants,
provide
effective
means
to
reduce
ARB,
yet
there
is
growing
need
for
additional
preventive
measures
directly
on
surfaces.
This
review
explores
the
potential
chitosan–phytochemical
composites
(CPCs)
surface
coatings
prevent
initial
by
thereby
offering
novel
complementary
approach
conventional
safety
practices.
Chitosan,
combined
with
active
plant-derived
metabolites
(phytochemicals),
forms
notable
antibacterial
antioxidant
properties
that
enhance
its
protective
effects.
We
examine
CPC
synthesis
methodologies,
including
modifications,
free
radical-induced
grafting,
enzyme-mediated
techniques,
which
stability
activity
CPCs
against
ARB.
Highlighting
recent
findings
CPCs’
efficacy
through
minimum
inhibitory
concentrations
(MIC)
zones
inhibition,
this
underscores
ARB
risks
surfaces,
seafood,
meat,
postharvest
products.
insights
provided
here
aim
encourage
future
strategies
leveraging
preventative
treatment
mitigate
production
processing
environments.
