Toxicity and Safety Aspects of Inulin
Опубликована: Янв. 1, 2025
Язык: Английский
Inulin as a Biopolymer; Chemical Structure, Anticancer Effects, Nutraceutical Potential and Industrial Applications: A Comprehensive Review
Polymers,
Год журнала:
2025,
Номер
17(3), С. 412 - 412
Опубликована: Фев. 4, 2025
Inulin
is
a
versatile
biopolymer
that
non-digestible
in
the
upper
alimentary
tract
and
acts
as
bifidogenic
prebiotic
which
selectively
promotes
gut
health
modulates
gut–organ
axes
through
short-chain
fatty
acids
possibly
yet-to-be-known
interactions.
usage
fiber
ingredient
food
has
been
approved
by
FDA
since
June
2018
it
predicted
universal
inulin
market
demand
will
skyrocket
near
future
because
of
its
novel
applications
diseases.
This
comprehensive
review
outlines
known
various
disciplines
ranging
from
medicine
to
industry,
covering
benefits
diseases,
metabolism,
drug
delivery,
therapeutic
pharmacology,
nutrition,
prebiotics
industry.
Furthermore,
this
acknowledges
attention
researchers
knowledge
gaps
regarding
usages
key
modulator
axes.
Язык: Английский
The Utilization of Biopolymer Hydrogels to Encapsulate and Protect Probiotics in Foods
Process Biochemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 1, 2025
Язык: Английский
Comprehensive Biosafety Profile of Carbomer-Based Hydrogel Formulations Incorporating Phosphorus Derivatives
Gels,
Год журнала:
2024,
Номер
10(7), С. 477 - 477
Опубликована: Июль 18, 2024
Determining
the
safety
of
a
newly
developed
experimental
product
is
crucial
condition
for
its
medical
use,
especially
clinical
trials.
In
this
regard,
four
hydrogel-type
formulations
were
manufactured,
all
which
based
on
carbomer
(Blank-CP940)
and
encapsulated
with
caffeine
(CAF-CP940),
phosphorus
derivatives
(phenyl
phosphinic
(CAF-S1-CP940)
2-carboxyethyl
phenyl
acids
(CAF-S2-CP940)).
The
main
aim
research
was
to
provide
comprehensive
outline
biosafety
profile
above-mentioned
hydrogels.
complex
in
vitro
screening
(cell
viability,
cytotoxicity,
morphological
changes
response
exposure,
nuclei
morphology)
two
types
healthy
skin
cell
lines
(HaCaT-human
keratinocytes
JB6
Cl
41-5a-murine
epidermal
cells)
exhibited
good
when
both
treated
24
h
150
μg/mL
each
hydrogel.
A
analysis
hydrogel's
impact
genetic
HaCaT
cells
sustains
experiments.
completed
vivo
ovo
assays.
outcome
revealed
that
hydrogels
exerted
biocompatibility
after
topical
application
BALB/c
nude
mice's
skin.
It
also
lack
toxicity
exposure
hen's
chicken
embryo.
Further
investigations
are
needed,
regarding
therapeutic
efficacy
long-term
use
potential
translatability.
Язык: Английский
Inulin biopolymer as a novel material for sustainable soil stabilization
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Дек. 28, 2024
The
development
of
new
urban
areas
necessitates
building
on
increasingly
scarce
land,
often
overlaid
weak
soil
layers.
Furthermore,
climate
change
has
exacerbated
the
extent
global
arid
lands,
making
it
imperative
to
find
sustainable
stabilization
and
erosion
mitigation
methods.
Thus,
scientists
have
strived
a
plant-based
biopolymer
that
favors
several
agricultural
waste
sources
provides
high
strength
durability
for
stabilization.
This
contribution
is
one
first
studies
assessing
feasibility
using
inulin
stabilize
mitigate
erosion.
Inulin
sources,
alternative
traditional
additives.
Soil
samples
susceptible
wind
were
collected
from
dust-prone
area
in
southwest
Iran
treated
with
at
0%,
0.5%,
1%,
2%
by
weight.
Their
mechanical
was
evaluated
unconfined
compressive
tests
penetrometer.
In
addition,
tunnel
(at
16
m/s)
performed
investigate
inulin's
potential.
after
ten
wetting–drying
cycles
assess
effect
environmental
stressors.
results
indicated
40-fold
increase
(up
8
MPa)
only
0.22%
weight
loss
cycles.
SEM
images
revealed
formation
biopolymer-induced
particle-to-particle
bonds.
Moreover,
Raman
spectroscopy
molecular
(hydrogen)
bonding
hydrogel-soil
particles
facilitated
hydroxyl
groups
inulin.
deterioration
stiffness
less
noticeable
3rd
dry–wet
cycle,
indicating
samples.
against
wet–dry
attributed
soil-biopolymer
hydrogel,
as
FTIR
analysis.
Язык: Английский