Development and Characterization of Antimicrobial Chitosan/Polyethylene Oxide/Bacterial Cellulose Nanofibers DOI Open Access

Fatma Coşar Çetin,

Tubanur Avci, Emre Uygur

и другие.

Polymers, Год журнала: 2025, Номер 17(5), С. 693 - 693

Опубликована: Март 5, 2025

This study introduces novel chitosan (CS) and polyethylene oxide (PEO) copolymers reinforced with bacterial cellulose (BC) to fabricate nanofibers using the electrospinning method. SEM analysis confirmed uniform nanofiber formation, CS/PEO/BC (~240 nm) exhibiting a larger diameter than CS/PEO ones (~190 nm). FTIR spectroscopy BC integration, while Differential scanning calorimetry indicated minimal impact on glass transition temperature. Notably, as compared nanofibers, demonstrated superior swelling capacity, accelerated biodegradation, enhanced mechanical (i.e., tensile) properties, maximum stress strain values of ~3.41 MPa ~0.01% vs. ~2.14 ~0.01%. Antimicrobial assays activity against strains, biocompatibility tests showed high cell viability at day seven (99.26% for nanofibers). These findings highlight potential promising candidates tissue engineering, offering improved strength, biodegradability, antimicrobial properties.

Язык: Английский

Development and Characterization of Antimicrobial Chitosan/Polyethylene Oxide/Bacterial Cellulose Nanofibers DOI Open Access

Fatma Coşar Çetin,

Tubanur Avci, Emre Uygur

и другие.

Polymers, Год журнала: 2025, Номер 17(5), С. 693 - 693

Опубликована: Март 5, 2025

This study introduces novel chitosan (CS) and polyethylene oxide (PEO) copolymers reinforced with bacterial cellulose (BC) to fabricate nanofibers using the electrospinning method. SEM analysis confirmed uniform nanofiber formation, CS/PEO/BC (~240 nm) exhibiting a larger diameter than CS/PEO ones (~190 nm). FTIR spectroscopy BC integration, while Differential scanning calorimetry indicated minimal impact on glass transition temperature. Notably, as compared nanofibers, demonstrated superior swelling capacity, accelerated biodegradation, enhanced mechanical (i.e., tensile) properties, maximum stress strain values of ~3.41 MPa ~0.01% vs. ~2.14 ~0.01%. Antimicrobial assays activity against strains, biocompatibility tests showed high cell viability at day seven (99.26% for nanofibers). These findings highlight potential promising candidates tissue engineering, offering improved strength, biodegradability, antimicrobial properties.

Язык: Английский

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