Smart packaging containing red poppy anthocyanins for fish freshness monitoring

Journal of Food Measurement & Characterization, Год журнала: 2024, Номер 18(4), С. 3054 - 3068

Опубликована: Фев. 1, 2024

Язык: Английский

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Designing, Characterization, DFT, Biological Effectiveness, and Molecular Docking Analysis of Novel Fe(III), Co(II), and Cu(II) Complexes Based on 4-Hydroxy-2H-pyrano[3,2-c]quinoline-2,5(6H)-dione

ACS Omega, Год журнала: 2024, Номер 9(6), С. 6466 - 6481

Опубликована: Фев. 1, 2024

The main target of the current framework is designing and synthesizing novel iron(III), cobalt(II), cupper(II) complex compounds emanating from bioactive nucleus, 4-hydroxy-2H-pyrano[3,2-c]quinoline-2,5(6H)-dione ligand, to enhance comprehension as potential antibacterial, antifungal, antioxidant alternatives by means using DFT calculations molecular docking investigation. Thus, new complexes had been synthesized characterized various analytical techniques, including elemental analysis, infrared spectroscopy, mass spectrometry, UV conductivity, magnetic testing, well thermal analysis. ligand exhibits monobasic bidentate OO donor properties toward metal core, shown its spectroscopic characteristics. use analysis techniques allows for identification characterization water molecules present inside complexes, determination their distribution patterns. structures free have verified through density functional theory (DFT) simulations. These simulations also provide a valuable understanding quantum chemical characteristics associated with these structures. In vitro experiments were conducted evaluate antioxidant, antifungal corresponding compounds. DATA revealed that heightened biological efficacy related unbound ligand. Furthermore, was done understand interactions between studied proteins derived Escherichia coli (pdb ID: 2vf5), Aspergillus flavus 3cku), humans 5IJT), which are considered be significant in drug design. Lastly, correlation efficacies data analyzed.

Язык: Английский

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Determination of Antioxidant, Antidiabetic, Anticholinergic, Antiglaucoma Properties and Comprehensive Phytochemical Content by LC‐MS/MS of Bingöl Honeybee Pollen

Food Science & Nutrition, Год журнала: 2025, Номер 13(3)

Опубликована: Март 1, 2025

Honeybee pollen is the most important food and protein source for bees. It a highly nutritious natural product humans due to its content. Pollen shows different phytochemical content variable biological activity according geography vegetation. Therefore, in this study, comprehensive by LC-MS/MS, antioxidant properties assays, with enzyme inhibition potential; antidiabetic, anticholinergic, antiglaucoma properties, were determined from sample Bingöl province, one of significant beekeeping centers Türkiye. As result 15 metabolites determined, highest concentration quinic acid (1.531 mg analyte/g extract) was found. Antioxidant results: total phenolic 113.14 GAE/g, flavonoid 64.11 QE/g, Fe3+ reduction 0.43 μg/mL, CUPRAC 0.511 FRAP 0.976 DPPH IC50: 1.06 ABTS 0.933 DMPD 0.598 μg/mL. In addition, showed antiglaucoma, antidiabetic inhibiting carbonic anhydrase isoenzyme II (hCA II), acetylcholinesterase (AChE), α- amylase enzymes, respectively. it that has and, first time, inhibits hCA II, AChE, α-amylase enzymes.

Язык: Английский

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Synthesis, characterization, DFT, biological activity evaluation, and molecular docking analysis of new 8-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1,3-disulfonic acid based complexes

Journal of Molecular Structure, Год журнала: 2023, Номер 1300, С. 137175 - 137175

Опубликована: Ноя. 28, 2023

Язык: Английский

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Comparative antioxidant activity and phytochemical content of five extracts of Pleurotus ostreatus (oyster mushroom)

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Фев. 15, 2024

Abstract Reactive oxygen species reacts with numerous molecules in the body system causing oxidative damage, which requires antioxidants to ameliorate. Pleurotus ostreatus , a highly nutritious edible mushroom, has been reported be rich bioactive compounds. This study evaluated comparative antioxidant activity and phytochemical contents of five extracts P. : aqueous (AE), chloroform (CE), ethanol (EE), methanol (ME) n-hexane (HE). The composition were determined using standard in-vitro assay methods. Results showed that contained alkaloids, tannins, saponins, flavonoids, terpenoids, phenolics, cardiac glycosides, carbohydrates, anthrocyanins, betacyanins varied amounts. CE had highest flavonoid content (104.83 ± 29.46 mg/100 g); AE gave phenol 24.14 0.02 g; tannin was EE (25.12 0.06 HE amounts alkaloids (187.60 0.28 g) saponins (0.16 0.00 g). Antioxidant analyses revealed best hydroxyl radical 250% at 100 µg/ml ferric cyanide reducing power 8495 µg/ml; ME maximum DPPH (87.67%) hydrogen peroxide scavenging (65.58%) 500 nitric oxide inhibition 65.81% ascorbate peroxidase 1.60 (iU/l). total capacity (5.27 GAE µg/ml) ferrous iron chelating (99.23% while guaiacol 0.20(iU/l). characteristics (IC 50 ) followed order: > HE. Overall, extraction solvent for . high phenolic compounds, makes it source potential candidate development new therapies variety stress-related disorders.

Язык: Английский

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Synthesis, characterization, and comprehensive computational analysis of aromatic hydrazone compounds: Unveiling quantum parameters, evaluating antioxidant activity, and investigating molecular docking interactions

Journal of Molecular Liquids, Год журнала: 2024, Номер 403, С. 124897 - 124897

Опубликована: Май 3, 2024

Язык: Английский

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Evaluating the biological (antidiabetic) potential of TEM, FTIR, XRD, and UV‐spectra observed berberis lyceum conjugated silver nanoparticles

Microscopy Research and Technique, Год журнала: 2024, Номер 87(6), С. 1286 - 1305

Опубликована: Фев. 14, 2024

Abstract Diabetes is a life‐threatening disease that affects different parts of the body including liver, kidney, and pancreas. The core root diabetes mainly linked to oxidative stress produced by reactive oxygen species (ROS). Berberis lyceum Royle (BLR) source natural products. It comprises numerous bioactive compounds having antioxidant activities. In current investigation, silver nanoparticles from BLR extract were synthesized, characterized, assessed for antidiabetic potential. UV spectrophotometry, Transmission electron microscopy (TEM), Fourier transform infra‐red spectroscopy (FTIR), x‐ray diffraction (XRD) applied characterization NPs. was evident morphological studies synthesized NPs spherical average size 11.02 nm. Results revealed BLR‐AgNPs showed higher radical scavenging activity as compared extract. Moreover, displayed superior in vivo vitro comparison Glucose level (116.5 ± 5.1 mg/dL), liver function test (ALAT: 54.038 6.2 IU/L; ASAT: 104.42 13.9 ALP: 192.6 2.4 bilirubin: 1.434 0.14 mg/dL; total protein: 5.14 0.24 renal (urea: 39.6 0.63 uric acid: 21.4 0.94 creatinine: 0.798 0.03 albumin: 4.14 0.2 lipid profile (cholesterol: 101.62 3 triglyceride: 110.42 7 HDL‐C: 29.7 LDL‐C: 47.056 1 VLDL‐C: 22.0 1.3 mg/dL) hematology (WBCs: 3.82 10 /μL; RBCs: 4.78 0.42 6 Hb: 12.6 1.0 g/dL; Hematocrit: 39.4 3.7%; MCV: 65.8 fL; platelets: 312 22.4; neutrophils: 34.8 1.87; eosinophils: 3.08 0.43; monocytes: 0.28; lymphocytes: 75.6 3.77) confirmed significant potential BLR‐AgNPs. Histopathological examination authenticated caused revival morphology Hence, findings study suggested potent agent could be an appropriate nanomedicine prevent future. Research Highlights reducing, capping, stabilization synthesis Evaluation α‐amylase inhibition, antioxidant, α‐glucosidase inhibition Thorough using infrared spectroscopy, microscopy, diffraction, UV–VIS spectrophotometer, which st its kind In‐vivo evaluation through multiple biomarkers

Язык: Английский

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Bioactive properties and gut microbiota modulation by date seed polysaccharides extracted using ultrasound-assisted deep eutectic solvent

Food Chemistry X, Год журнала: 2024, Номер 22, С. 101354 - 101354

Опубликована: Апрель 4, 2024

Polysaccharides are abundant macromolecules. The study extracted date seed polysaccharides (UPS) using ultrasound-assisted deep eutectic solvent extraction to valorize seeds. UPS were subjected comprehensive characterization and evaluation of their bioactivity, prebiotic properties, potential modulate the gut microbiome. Characterization revealed UPS's heteropolysaccharide composition with galactose, mannose, fructose, glucose, galacturonic acid respectively in 66.1, 13.3, 9.9, 5.4, 5.1%. showed a concentration-dependent increase radical scavenging antioxidant activities, evidenced by FRAP, TAC, RP assays. They also displayed antimicrobial efficacy against E. coli O157:H7, S. typhimurium, aureus, L. monocytogenes. Rheological analysis elastic-dominant nature thixotropic tendencies. inhibited α-glycosidase, α-amylase, ACE up 86%, reduced Caco-2 MCF-7 cell viability 70% 46%, respectively. favored beneficial microbiota growth, releasing significant SCFAs during fecal fermentation.

Язык: Английский

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Harnessing two-dimensional magnetic Poly(deep eutectic solvents) for matrix solid-phase dispersion extraction of polyphenols from roselle: Promoting antiphotoaging strategy

Chemical Engineering Journal, Год журнала: 2024, Номер 496, С. 154019 - 154019

Опубликована: Июль 19, 2024

Язык: Английский

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Harnessing advanced nanomaterials: Wastewater treatment with sustainable approach using 2D g-C3N4 based Ho-doped LaCoO3 nanocomposite

Ceramics International, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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