Ecotoxicology and Environmental Safety,
Год журнала:
2024,
Номер
283, С. 116828 - 116828
Опубликована: Авг. 1, 2024
The
neonicotinoid
pesticide
acetamiprid
has
been
widely
used
in
agricultural
pest
control
and
was
frequently
detected
the
water
environment.
There
have
some
studies
of
toxic
effects
on
fish,
but
aquatic
lower
vertebrates
are
still
very
limited.
As
a
primitive
jawless
vertebrate,
Lethenteron
reissneri
special
position
evolution
is
now
listed
as
national
second
level
protected
animal
China.
present
study
aimed
to
investigate
effect
liver
L.
larvae.
A
conjoint
analysis
transcriptomics
metabolomics
performed
determine
responses
larvae
at
different
concentrations
(L
for
low
concentration
25
mg/L
H
high
100
mg/L).
Even
can
cause
significant
damage
short
period.
In
omics
analyses,
2141
differentially
expressed
genes
(DEGs)
183
abundant
metabolites
(DAMs)
were
identified
H/Control
group,
229
DEGs
144
DAMs
L/C
group.
Correlation
analyses
revealed
affected
metabolic
pathways
such
glycerophospholipid
metabolism
arachidonic
acid
metabolism.
This
not
only
enriches
basis
understanding
exposure
provides
more
information
breeding
conservation
reissneri,
also
further
causes
attention
toxicity
risk
from
vertebrate
species.
Frontiers in Plant Science,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 2, 2024
While
the
pesticide
formulations
are
widely
used
for
pest
control,
combined
effects
of
these
with
adjuvants
on
droplet
behavior,
spraying
characteristics,
and
control
still
need
to
be
studied.
To
clarify
their
impact
efficacy,
six
acetamiprid
were
examined.
A
series
laboratory
field
experiments
conducted
analyze
physicochemical
properties,
toxicity
against
cotton
aphids,
deposition
drift.
The
results
indicated
that
5%
micro-emulsion
(ME)
enhanced
features
effectiveness
in
compared
other
formulations.
nongjianfei
considerably
efficiency
all
when
added.
addition
selected
improved
performance
certain
properties
such
as
viscosity
surface
tension
led
higher
aphid
mortality
rates,
demonstrating
during
present
study.
In
experiments,
combination
effect
exhibited
a
size,
coverage,
density
within
canopy.
However,
ME
was
found
most
effective
followed
by
nongjianfei.
Furthermore,
adjuvant
reduced
drift
provided
better
Overall,
specific
spray
drift,
increased
deposition.
These
findings
highlighted
significance
selecting
appropriate
solid
foundation
efficient
through
UAVs.
Environmental Toxicology and Pharmacology,
Год журнала:
2024,
Номер
unknown, С. 104606 - 104606
Опубликована: Дек. 1, 2024
Neonicotinoid
insecticides
(NNIs)
are
the
fastest-growing
class
in
agricultural
protection.
They
target
nicotinic
acetylcholine
receptors
(nAChR)
pests,
stimulating
nervous
system
at
low
doses
and
causing
paralysis
death
higher
concentrations.
NNIs
used
crop
protection,
seed
treatment,
forestry,
agriculture,
flea
control
domestic
cattle.
Effective
lower
concentrations
offering
long-term
control,
favoured
for
their
systemic
activity.
However,
due
to
water
solubility,
mobility,
moderate
persistence,
easily
contaminate
adjacent
aquatic
environments
via
runoff,
leaching,
or
spray
drift.
While
less
toxic
vertebrates,
widespread
use
poses
threats
terrestrial
organisms,
neurotoxicity,
nephrotoxicity,
cytotoxicity,
genotoxicity,
immunotoxicity,
hepatotoxicity,
endocrine
disruption,
reproductive
malformations.
This
review
synthesizes
research
address
knowledge
gaps
on
environmental
impact
of
proposes
policies
mitigate
harmful
effects
non-target
species.
Environment International,
Год журнала:
2024,
Номер
189, С. 108811 - 108811
Опубликована: Июнь 10, 2024
China
produces
and
consumes
a
large
amount
of
neonicotinoids.
A
non-negligible
exposure
to
neonicotinoids
might
occur
for
Chinese
pregnant
women,
but
relevant
data
remain
limited.
To
investigate
the
by
urinary
biomonitoring
in
women
from
Wenzhou
City,
East
China.
We
selected
432
City
2022.
total
eight
parent
four
metabolites
were
determined
single
spot
urine
liquid
chromatography
coupled
mass
spectrometry.
Basic
characteristics,
physical
activity,
pre-pregnant
body
index,
intake
drinking
water
food
investigated
questionnaire.
Health
risk
was
assessed
hazard
quotient
(HQ)
index
(HI)
based
on
human
safety
thresholds
derived
different
health
endpoints.
Neonicotinoids
their
had
detection
frequency
between
0
%
80.1
%.
At
least
one
neonicotinoid
or
metabolite
detected
93.5
samples.
Except
clothianidin
(51.2
%)
N-desmethyl-acetamiprid
(80.1
%),
frequencies
other
ranged
43.8
The
summed
concentrations
all
<
LOD
222.83
μg/g
creatinine
with
median
concentration
2.58
creatinine.
Maternal
age,
educational
level,
occupation,
household
income,
screen
time,
associated
metabolites.
Pregnant
higher
consumption
wheat,
fresh
vegetable,
shellfish,
milk,
powdered
milk
Both
HQ
HI
less
than
one.
Overall,
showed
notable
at
neonicotinoid,
although
each
specific
generally
low.
Several
items
plants
animals
potential
sources.
low
found
current
thresholds.
The European Zoological Journal,
Год журнала:
2025,
Номер
92(1), С. 61 - 73
Опубликована: Янв. 8, 2025
The
widespread
and
uncontrolled
application
of
neonicotinoid
pesticides
represents
a
major
threat
to
freshwater
ecosystems,
especially
those
near
agricultural
lands
farms.
Here,
we
determined
for
the
first
time
mean
lethal
concentration
(LC50–96
h)
acetamiprid
on
bleak
Alburnus
alburnus
juveniles
investigated
effect
gills
two
environmentally
relevant
concentrations
after
short-term
exposure
(96
h).
After
defining
LC50
value
(34.546
mg/L),
evaluated
effects
low
(150
300
µg/L)
through
histological
examination
molecular
evaluation
Na+/K+-ATPase
expression
in
gills.
No
morphological
alterations
were
observed
control
group.
Severe
structural
modifications
samples
exposed
both
tested
concentrations,
including
hyperplasia
hypertrophy
chloride
cells,
epithelial
detachment
aneurysm
formation,
which
are
recognised
as
common
early
response
chemical
insults.
Exposure
highest
induced
more
severe
damage,
with
appearance
necrotic
pavement
cells
degeneration
pillar
cells.
downregulation
was
following
concentrations.
Our
results
highlight
importance
expanding
panel
ecotoxicological
tests
required
approve
agrochemical
compounds
using
different
diagnostic
tools
an
in-depth
xenobiotic
toxicity.
Biology,
Год журнала:
2025,
Номер
14(2), С. 147 - 147
Опубликована: Янв. 30, 2025
The
impact
of
agrochemicals
on
pollinators,
especially
honey
bees,
has
drawn
significant
attention
due
to
its
critical
implications
for
worldwide
food
stability
and
ecosystems.
Given
the
potential
threat
insecticides
bees
may
encounter
multiple
simultaneously
during
foraging.
This
study
investigated
toxic
effect
an
insecticide
mixture
(IM)
containing
acetamiprid
(neonicotinoid)
deltamethrin
(pyrethroid)
survival
cognitive
appetitive
performance
Apis
mellifera
jemenitica,
a
vital
native
pollinator
in
arid
regions
Saudi
Arabia.
lethal
concentration
(LC50)
was
determined
by
assessing
bees’
mortality
rates
following
exposure
IM
through
topical
oral
routes.
Significant
bee
occurred
at
4–48
h
post
treatment
with
both
routes,
showing
trend
increased
higher
concentrations
compared
control
bees.
Throughout
all
tested
times,
proved
relatively
more
effective,
resulting
significantly
greater
IM.
Food
intake
declined
progressively
rising
exposure.
LC50
values
24
after
were
12.24
ppm
10.45
corresponding
LC10,
LC20,
LC30
3.75
ppm,
5.63
7.54
2.45
4.04
5.78
exposure,
respectively.
combination
index
(CI)
revealed
synergistic
(0.43)
antagonistic
effects
(1.43)
highlighting
differential
toxicity
dynamics.
impaired
acquisition
memory
reinforcement
as
demonstrated
behavioral
assays,
indicating
neurotoxic
effects.
Learning
formation
2,
12,
sublethal
Thus,
evaluating
interactive
pesticides
health
function
is
essential,
particularly
where
diverse
are
routinely
utilized.
Previously
synthesized
and
tested
water-dispersible
photoactive
polymeric
microparticles
have
been
employed
as
heterogenous
photosensitizers
to
evaluate
their
performance
in
generating
singlet
oxygen
through
direct
solar
irradiation.
This
study
utilizes
these
photocatalysts
for
the
degradation
of
Acetamiprid
IWWTP
wastewater
effluents
from
Agri-food
industry,
exploring,
addition
or
simulated
irradiation,
influence
pH
on
photooxidation
process.
Over
a
thousand
emerging
pollutants,
including
pesticides
like
Acetamiprid,
detected
aquatic
environments
recent
years,
posing
challenges
due
limitations
current
treatment
technologies.
The
developed
method
is
particularly
effective
under
basic
slightly
conditions,
aligning
with
natural
addressing
limitation
conventional
methods,
which
typically
require
medium
acidification
be
effective.
Polymers
P3
P4
exhibited
high
photocatalytic
activity,
achieving
over
99%
oxidation
via
generated
by
Rose
Bengal
supported
polymer
matrix,
while
maintaining
catalytic
efficiency
across
multiple
cycles.
results
confirm
that
removal
industrial
irradiation
feasible,
though
constrained
availability
sufficient
sunlight
hours.
Toxicology Reports,
Год журнала:
2025,
Номер
14, С. 101983 - 101983
Опубликована: Март 15, 2025
Thiamethoxam
(TMX),
a
widely
used
second-generation
neonicotinoid
insecticide,
has
raised
concerns
due
to
its
toxic
effects
on
non-target
species,
including
mammals.
Its
prolonged
use
is
associated
with
hepatotoxicity,
nephrotoxicity,
and
reproductive
damage.
This
study
evaluates
the
dose-dependent
biochemical,
histopathological,
genetic
of
TMX
in
male
albino
rats,
emphasizing
impact
liver,
kidney,
systems.
Forty
Wistar
rats
were
assigned
control
three
experimental
groups
treated
at
26,
39,
78
mg/kg/day
over
eight
weeks.
Key
biochemical
markers
such
as
Alanine
transaminase
(ALT),
Aspartate
(AST),
urea,
creatinine
oxidative
stress
indicators
(Catalase
(CAT),
Glutathione
(GSH),
Malondialdehyde
(MDA),
parameters
(testosterone,
sperm
count,
motility)
analyzed.
Histopathological
examination
testes
was
performed,
alongside
evaluation
Deoxyribonucleic
Acid
(DNA)
damage
testicular
tissue.
exposure
caused
significant
increases
liver
kidney
function
stress.
Reproductive
toxicity
evident,
reduced
testosterone
levels,
impaired
parameters,
histopathological
Notably,
induced
DNA
tissue,
indicated
by
increased
levels
8-hydroxy-2'-deoxyguanosine.
highlights
TMX's
systemic
manner,
key
mechanisms.
The
findings
underscore
need
for
stricter
regulatory
measures
further
exploration
protective
strategies
mitigate
TMX-induced
toxicity.