Age-Related Variations and Seasonal Influences: A Network Analysis of Comorbidities in Asthma Hospitalizations (2013–2023)
Journal of Clinical Medicine,
Год журнала:
2025,
Номер
14(7), С. 2350 - 2350
Опубликована: Март 29, 2025
Background:
Asthma,
a
chronic
respiratory
disease
characterized
by
airway
inflammation
and
hyperresponsiveness,
exhibits
significant
heterogeneity
in
its
presentation.
This
study
aimed
to
investigate
age-related
comorbidity
patterns,
seasonal
variations,
demographic
trends
among
cohort
of
asthma
patients
within
defined
geographical
region.
Methods:
A
retrospective
analysis
13,695
admitted
Romanian
hospital
from
2013
2023
was
conducted.
Comorbidity
patterns
were
analyzed
using
network
across
age
groups,
investigated
through
spectral
analysis.
Results:
Asthma
admissions
exhibited
non-linear
with
female
predominance
(57.72%).
The
pandemic
significantly
impacted
admission
rates,
males
experiencing
greater
COVID-19-related
effects.
Female
showed
distinct
potentially
linked
domestic
responsibilities.
evolved
age,
shifting
lifestyle
factors
younger
complex
cardiovascular
neurological
disorders
older
groups.
60-69
group
the
highest
integration
communities.
Conclusions:
revealed
that
management
focus
should
shift
patient
itself
addressing
underlying
comorbidities.
Understanding
these
may
help
personalize
treatment
strategies
improve
long-term
prognosis
for
patients.
Язык: Английский
Effects of Exposure to Air Pollution and Cold Weather on Acute Myocardial Infarction Mortality
Atmosphere,
Год журнала:
2025,
Номер
16(4), С. 469 - 469
Опубликована: Апрель 17, 2025
(1)
Background:
Human
exposure
to
air
pollution
may
induce
inflammation
and
oxidative
stress.
In
addition,
extreme
temperatures
relative
humidity
cause
vasoconstriction
abnormal
blood
cell
function.
These
harmful
effects
increase
cardiovascular
disease
mortality.
The
of
climatic
factors
on
mortality
in
patients
with
acute
myocardial
infarction
(AMI)
are
relatively
unknown.
(2)
Methods:
We
used
AMI
data
collected
from
Taiwan’s
Medical
Quality
Indicator.
Air
pollutant
were
the
Taiwanese
Environmental
Protection
Administration,
temperature
obtained
Central
Weather
Administration.
estimated
using
Poisson
regression
analyze
risk
(RR)
associated
pollutants
factors.
(3)
Results:
RR
for
every
4.7
μg/m3
particulate
matter
a
diameter
less
than
2.5
μm
(PM2.5)
was
1.086
(95%
CI:
1.033–1.142,
p
=
0.001).
10.3
ppb
ozone
concentration
1.095
1.011–1.185,
0.025).
6.5
°C
decrease
1.087
1.024–1.154,
0.006)
(4)
Conclusions:
This
study
revealed
that
higher
PM2.5
concentrations,
along
cold
weather,
individuals
AMI.
government
must
develop
policies
promote
prevention,
mitigate
pollution,
alert
residents
about
poor
quality
thereby
promoting
sustainable
human
health.
Язык: Английский
Seasonal variation of pediatric asthma exacerbations and its association with asthma phenotypes
Pediatric Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 7, 2025
Abstract
Background
The
objective
of
this
study
was
to
examine
the
associations
blood
inflammatory
phenotypes
with
acute
pediatric
asthma
exacerbations
during
different
seasons
and
COVID-19
pandemic.
Methods
A
retrospective
conducted
involving
32,160
patients
from
January
2008
December
2021.
Asthma
were
categorized
based
on
low
(L)
high
(H)
eosinophils
(E)
neutrophils
(N)
(LBE/HBE:
≥
0.25
×
10
9
/L
LBN/HBN:
5
/L,
respectively)
logistic
regression
used
odds
ratio
(OR)
outcome
variables.
Results
increase
associated
a
1.015-fold
(95%
CI:
1.009–1.021)
1.057-fold
in
OR
1.026–1.088)
for
hospitalized
patients.
An
HBE/LBN
phenotype
respective
1.232-fold
1.081–1.404)
1.248-fold
1.101–1.414)
before
pandemic
winter
autumn
seasons.
However,
an
LBE/LBN
0.873-fold
0.769–0.991),
0.872-fold
0.771–0.986),
0.813-fold
0.709–0.932)
decrease
winter,
spring
summer
Conclusions
had
higher
risk
among
autumn,
while
lower
spring,
summer.
Impact
Blood
have
been
indicated
potential
influence
development
severity.
increased
autumn.
Eosinophil
neutrophil
predominance
exhibited
exacerbations.
Язык: Английский
Impact of Foodborne Disease in Taiwan during the COVID-19 Pandemic
Ya-Lu Yang,
Cheng-Chueh Chen,
Pi-Wei Chin
и другие.
Medicina,
Год журнала:
2024,
Номер
60(3), С. 505 - 505
Опубликована: Март 19, 2024
Background
and
Objectives:
The
coronavirus
disease
2019
(COVID-19)
pandemic
originated
in
Wuhan,
China,
December
2019,
the
first
case
diagnosed
since
January
2020
Taiwan.
study
about
potential
impact
of
COVID-19
on
event,
location,
food
source,
pathogens
foodborne
(FBD)
is
limited
Our
aim
this
to
investigate
FBD
context
pandemic.
Materials
Methods:
We
collected
publicly
available
annual
summary
data
from
dataset
Taiwan
Food
Drug
Administration
Certifiable
Disease
reported
2020.
used
logistic
regression
evaluate
changes
occurrence
or
likelihood
cases
Poisson
examine
relative
risk
(RR)
between
climate
factors.
Results:
Similar
events
occurred
2020,
but
total
number
decreased
6935
4920
places
where
were
schools,
hospitals,
outdoors,
vendors,
exteriors.
top
place
shifted
schools
restaurants.
source
for
has
changed
boxed
compound
food.
Bacillus
cereus
Salmonella
emerged
as
two
observed
bacterial
causing
FBD.
increased
with
a
higher
air
temperature,
an
RR
1.055
(1.05–1.061,
p
<
0.001)
every
1
°C.
Conclusion:
incidence
significantly
during
This
decline
may
be
attributed
protective
measures
implemented
control
spread
virus.
shift
locations
could
influenced
by
public
behavior,
regulations,
other
external
emphasizes
importance
understanding
sources
effectiveness
severe
infection
prevention
policies.
government
can
use
these
findings
formulate
evidence-based
policies
aimed
at
reducing
promoting
health.
Consumers
reduce
following
safe
handling
preparation
recommendations.
Язык: Английский