Journal of Hazardous Materials Advances, Год журнала: 2024, Номер unknown, С. 100581 - 100581
Опубликована: Дек. 1, 2024
Язык: Английский
Toxics, Год журнала: 2024, Номер 12(8), С. 617 - 617
Опубликована: Авг. 21, 2024
Nanoplastics, as emerging environmental pollutants, can transport contaminants across marine environments, polluting pristine ecosystems and being ingested by organisms. This transfer poses a severe threat to global aquatic potentially impacts human health through the food chain. Neurobehavioral reproductive toxicity are critical areas of concern because they directly affect survival, health, population dynamics species, which have cascading effects on entire ecosystem. Using zebrafish model organism, we investigated toxic concentrations polystyrene nanoplastics (PS-NPs). Behavioral assessments, including novel tank test open field test, demonstrated significant neurobehavioral changes, indicating increased anxiety depressive behaviors. A pathological analysis brain gonadal tissues, along with evaluations biomarkers, revealed that exposure PS-NPs leads tissue lesions, inflammatory responses, oxidative stress activation, hormone level disruptions, damage. Real-time quantitative PCR studies gene expression further showed disrupt endocrine regulation pathways brain-pituitary-gonadal (BPG) axis, causing sex-specific differences. These findings provide crucial insights into organisms their ecological risks, offering theoretical support for future protection pollutant management efforts.
Язык: Английский
Процитировано
2
The Science of The Total Environment, Год журнала: 2024, Номер 953, С. 176223 - 176223
Опубликована: Сен. 11, 2024
Язык: Английский
Процитировано
1
Environmental Research, Год журнала: 2024, Номер 266, С. 120504 - 120504
Опубликована: Дек. 3, 2024
Язык: Английский
Процитировано
0
Journal of Hazardous Materials Advances, Год журнала: 2024, Номер unknown, С. 100581 - 100581
Опубликована: Дек. 1, 2024
Язык: Английский
Процитировано
0