Invisible but Insidious Effects of Microplastics DOI Creative Commons
Natalia A. Stefanova, Yulia S. Sotnikova,

Aleksandra E. Osechkova

и другие.

Molecules, Год журнала: 2024, Номер 29(23), С. 5776 - 5776

Опубликована: Дек. 6, 2024

Increasing evidence on the adverse health impacts of microplastics (MPs) is available, but their associated risks to well-being humans and long-term are poorly understood. An indicator remote effects MPs may be influence rate aging. To assess aging process, we used accelerated senescence OXYS rats that develop a complex geriatric diseases. We prepared polyethylene terephthalate (2-6 microns in size) Wistar (maternal strain) assessed chronic administration (10 or 100 mg/kg per day from age 1.5 3.5 months,) hematological biochemical blood parameters, spatial learning, memory. In addition, development cataracts retinopathy, similar age-related macular degeneration (AMD), were assessed. found absence significant changes standard clinical MP negatively affected cognitive functions both rats. Additionally, dose contributed cataract AMD progression Our results suggest increase and, long term, lifespan.

Язык: Английский

Cerebellar Pathology in Forensic and Clinical Neuroscience DOI
Azhagu Madhavan Sivalingam,

Darshitha D Sureshkumar

Ageing Research Reviews, Год журнала: 2025, Номер unknown, С. 102697 - 102697

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0
Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells DOI Creative Commons
Antonia Feola, Manoj Madheswaran,

G. Romano

и другие.

Heliyon, Год журнала: 2024, Номер 11(1), С. e41298 - e41298

Опубликована: Дек. 18, 2024

Язык: Английский

Процитировано

1
Invisible but Insidious Effects of Microplastics DOI Creative Commons
Natalia A. Stefanova, Yulia S. Sotnikova,

Aleksandra E. Osechkova

и другие.

Molecules, Год журнала: 2024, Номер 29(23), С. 5776 - 5776

Опубликована: Дек. 6, 2024

Increasing evidence on the adverse health impacts of microplastics (MPs) is available, but their associated risks to well-being humans and long-term are poorly understood. An indicator remote effects MPs may be influence rate aging. To assess aging process, we used accelerated senescence OXYS rats that develop a complex geriatric diseases. We prepared polyethylene terephthalate (2-6 microns in size) Wistar (maternal strain) assessed chronic administration (10 or 100 mg/kg per day from age 1.5 3.5 months,) hematological biochemical blood parameters, spatial learning, memory. In addition, development cataracts retinopathy, similar age-related macular degeneration (AMD), were assessed. found absence significant changes standard clinical MP negatively affected cognitive functions both rats. Additionally, dose contributed cataract AMD progression Our results suggest increase and, long term, lifespan.

Язык: Английский

Процитировано

0