Oxidative Stress, Genetic Factors and Behavioral Responses to Chemical Exposure: Insights into Cancer Development in Zebrafish (Danio Rerio) DOI Creative Commons
Cătălina Ionescu, Viorica Rarinca,

Mălina Visternicu

и другие.

Biochemical Genetics, Год журнала: 2025, Номер unknown

Опубликована: Июнь 3, 2025

Cancer research in animal models is critical for understanding disease mechanisms and testing potential therapies. Among the various models, zebrafish (Danio rerio) has gained prominence due to its genetic similarity humans, rapid development, transparency during early stages. The objective of this article explore as a powerful model studying cancer, particularly focusing on role oxidative stress (OS) factors (oncogenes, tumor suppressor genes) cancer progression. interaction between stress, DNA damage, mutations examined, highlighting how these processes contribute formation. Additionally, study investigates behavioral tests used assess effects carcinogenic non-carcinogenic substances, such sodium arsenate (As(V), N-ethyl-N-nitrosourea (ENU), dimethylbenzanthracene (DMBA), N-methyl-N1-nitro-N-nitrosoguanidine (MNNG), Atrazine Methylmercury (MeHg) cognitive functions. review included 170 papers published English up December 2024 was conducted accordance with PRISMA guidelines, using multiple electronic databases (Science Direct, PubMed Google Scholar) perform comprehensive systematic search keywords. Through approach, emerge versatile research, offering insights into both physiological impacts chemical exposures.

Язык: Английский

Oxidative Stress, Genetic Factors and Behavioral Responses to Chemical Exposure: Insights into Cancer Development in Zebrafish (Danio Rerio) DOI Creative Commons
Cătălina Ionescu, Viorica Rarinca,

Mălina Visternicu

и другие.

Biochemical Genetics, Год журнала: 2025, Номер unknown

Опубликована: Июнь 3, 2025

Cancer research in animal models is critical for understanding disease mechanisms and testing potential therapies. Among the various models, zebrafish (Danio rerio) has gained prominence due to its genetic similarity humans, rapid development, transparency during early stages. The objective of this article explore as a powerful model studying cancer, particularly focusing on role oxidative stress (OS) factors (oncogenes, tumor suppressor genes) cancer progression. interaction between stress, DNA damage, mutations examined, highlighting how these processes contribute formation. Additionally, study investigates behavioral tests used assess effects carcinogenic non-carcinogenic substances, such sodium arsenate (As(V), N-ethyl-N-nitrosourea (ENU), dimethylbenzanthracene (DMBA), N-methyl-N1-nitro-N-nitrosoguanidine (MNNG), Atrazine Methylmercury (MeHg) cognitive functions. review included 170 papers published English up December 2024 was conducted accordance with PRISMA guidelines, using multiple electronic databases (Science Direct, PubMed Google Scholar) perform comprehensive systematic search keywords. Through approach, emerge versatile research, offering insights into both physiological impacts chemical exposures.

Язык: Английский

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