Advanced neuromorphic engineering approaches for restoring neural activity after brain injury: innovations in regenerative medicine DOI
Alexander N. Pisarchik, Svetlana A. Gerasimova, Albina Lebedeva

и другие.

Regenerative medicine reports ., Год журнала: 2024, Номер 1(2), С. 195 - 210

Опубликована: Дек. 1, 2024

Restoring neural function after brain injury is a critical medical challenge, as conventional treatments often fail to achieve full recovery. This makes the development of innovative regenerative medicine and biomedical engineering strategies particularly necessary. study aims fill existing gap in neuromorphic by mimicking biological neuron dynamics realizing effective clinical applications promote functional recovery quality life enhancement patients with injury. The novel approaches leverage dynamic behavior neurons, incorporating electronic circuits that emulate neuronal dynamics. A basic configuration involves model designed mimic living neuron, potential replace damaged tissue when implanted, thus restoring signal propagation. An enhanced integrates closed-loop system, wherein feedback from neurons synchronizes artificial its counterpart, allowing continuous self-adjustment system parameters promoting neuro-autogenerative regime. Further refinement introduces memristive device connects simulate synaptic plasticity. In conjunction control, this enables self-tuning for improved adaptability natural supporting software combines nonlinear deep learning techniques, specifically employing reservoir computing performance. These were successfully validated vitro vivo using mice models, demonstrating advanced holds significant activity offers promising strategy improve rehabilitation outcomes patients’ aiding neurological reconstruction.

Язык: Английский

Machine Learning Opportunities in Traumatic Brain Injury Patients DOI Creative Commons

M. Marzia Noor,

Md Moshiur Rahman, Amit Agrawal

и другие.

Indian Journal of Neurotrauma, Год журнала: 2025, Номер unknown

Опубликована: Фев. 10, 2025

Язык: Английский

Процитировано

0

Advances of Artificial Intelligence in Neuroimaging DOI Creative Commons
Iman Beheshti, Daichi Sone, Carson K. Leung

и другие.

Brain Sciences, Год журнала: 2025, Номер 15(4), С. 351 - 351

Опубликована: Март 28, 2025

Neuroimaging [...]

Язык: Английский

Процитировано

0

Animal Models of Traumatic Brain Injury and Their Relevance in Clinical Settings DOI Creative Commons
Payal Chauhan,

Nikita Yadav,

Karan Wadhwa

и другие.

CNS Neuroscience & Therapeutics, Год журнала: 2025, Номер 31(4)

Опубликована: Апрель 1, 2025

ABSTRACT Background Traumatic brain injury (TBI) is a significant concern that often goes overlooked, resulting from various factors such as traffic accidents, violence, military services, and medical conditions. It major health issue affecting people of all age groups across the world, causing morbidity mortality. TBI highly intricate disease process causes both structural damage functional deficits. These effects result combination primary secondary mechanisms. responsible for range negative effects, impairments in cognitive function, changes social behavioural patterns, difficulties with motor skills, feelings anxiety, symptoms depression. Methods associated animal models were reviewed databases including PubMed, Web Science, Google scholar etc. The current study provides comprehensive overview commonly utilized examines their potential usefulness clinical context. Results Despite notable advancements outcomes over past two decades, there remain challenges evaluating, treating, addressing long‐term prevention this condition. Utilizing experimental crucial gaining insight into development progression TBI, it allows us to examine biochemical impacts on Conclusion This exploration can assist scientists unraveling mechanisms involved ultimately contribute advancement successful treatments interventions aimed at enhancing patients.

Язык: Английский

Процитировано

0

Advanced neuromorphic engineering approaches for restoring neural activity after brain injury: innovations in regenerative medicine DOI
Alexander N. Pisarchik, Svetlana A. Gerasimova, Albina Lebedeva

и другие.

Regenerative medicine reports ., Год журнала: 2024, Номер 1(2), С. 195 - 210

Опубликована: Дек. 1, 2024

Restoring neural function after brain injury is a critical medical challenge, as conventional treatments often fail to achieve full recovery. This makes the development of innovative regenerative medicine and biomedical engineering strategies particularly necessary. study aims fill existing gap in neuromorphic by mimicking biological neuron dynamics realizing effective clinical applications promote functional recovery quality life enhancement patients with injury. The novel approaches leverage dynamic behavior neurons, incorporating electronic circuits that emulate neuronal dynamics. A basic configuration involves model designed mimic living neuron, potential replace damaged tissue when implanted, thus restoring signal propagation. An enhanced integrates closed-loop system, wherein feedback from neurons synchronizes artificial its counterpart, allowing continuous self-adjustment system parameters promoting neuro-autogenerative regime. Further refinement introduces memristive device connects simulate synaptic plasticity. In conjunction control, this enables self-tuning for improved adaptability natural supporting software combines nonlinear deep learning techniques, specifically employing reservoir computing performance. These were successfully validated vitro vivo using mice models, demonstrating advanced holds significant activity offers promising strategy improve rehabilitation outcomes patients’ aiding neurological reconstruction.

Язык: Английский

Процитировано

0