Variability in COVID-19 symptom presentation during pregnancy and its impact on maternal and infant outcomes across the pandemic

International Journal of Infectious Diseases, Год журнала: 2024, Номер 146, С. 107157 - 107157

Опубликована: Июль 5, 2024

Язык: Английский

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Unraveling relevant cross-waves pattern drifts in patient-hospital risk factors among hospitalized COVID-19 patients using explainable machine learning methods

BMC Infectious Diseases, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 15, 2025

Язык: Английский

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Placental Infection Associated with SARS-CoV-2 Wildtype Variant and Variants of Concern

Viruses, Год журнала: 2023, Номер 15(9), С. 1918 - 1918

Опубликована: Сен. 13, 2023

The original SARS-CoV-2 lineages have been replaced by successive variants of concern (VOCs) over time. aim this study was to perform an assessment the placental infection according predominant variant at moment COVID-19 diagnosis. This a prospective SARS-CoV-2-positive pregnant women between March 2020 and 2022. population divided into pregnancies affected disease during (Pre-VOC group) after December (VOC group). presence virus assessed RT-PCR, viral determined whole genome sequencing. A total 104 placentas were examined, among which 54 cases belonged Pre-VOC group 50 VOC group. Sixteen positive RT-PCR tests for reported. NGS analysis confirmed lineage in placenta tissue. All samples corresponded group, whereas no detected (16, 29.6% vs. 0, 0.0% p = 0.000). Preterm birth (9, 16.7% 2, 4%; 0.036) hypertensive disorders pregnancy (14, 25.9% 3, 6%; 0.003) more frequent than Finally, composed 23 unvaccinated 27 vaccinated women; differences observed sub-analysis focused on vaccination status. In summary, only infected wildtype. Thus, could be influenced variants, timing, or According our data, current risk maternal COVID should updated.

Язык: Английский

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COVID-19 virus and clinical outcome on the newborns at the Neonatal Department of Intensive Medicine in Bratislava, Slovakia

Bratislavské lekárske listy/Bratislava medical journal, Год журнала: 2024, Номер 125(03), С. 189 - 195

Опубликована: Янв. 1, 2024

of Children´s Diseases in the period from 08.01.2021 until 07.07.2023 who were affected by COVID-19 virus mother before birth, staff or family only contact with positive person.RESULTS: Most common symptoms newborns within our findings included fever, upper respiratory symptoms, and diarrhoea.Detailed analysis prenatal postnatal characteristics, clinical are presented tables 1-3.CONCLUSION: pandemic had a great impact on pregnant women as well development child.Our results reveal that severity infected sample was low.It is important to implement adequate neonatal practices for early detection illnesses, especially relation which will subsequently allow intervention reduce mortality.Future challenges all countries include implementation higher hygiene standards, prevention spreading, more sensitive tests use first day life (Tab.3, Ref. 36).

Язык: Английский

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Challenges and Barriers to WIC Participation Vary by Participation Status and Language: Findings from focus groups in Missouri

Appetite, Год журнала: 2024, Номер unknown, С. 107838 - 107838

Опубликована: Дек. 1, 2024

Язык: Английский

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Recommendations for the Diagnosis and Treatment of Maternal SARS-CoV-2 Infection

Maternal-Fetal Medicine, Год журнала: 2023, Номер 5(2), С. 74 - 79

Опубликована: Фев. 28, 2023

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread worldwide and threatened human's health. With the passing of time, epidemiology disease 2019 evolves knowledge SARS-CoV-2 accumulates. To further improve scientific standardized diagnosis treatment maternal in China, Chinese Society Perinatal Medicine Medical Association commissioned leading experts to develop Recommendations for Diagnosis Treatment Maternal Infection under guidance Child Health Department National Commission. This recommendations includes epidemiology, diagnosis, management, care, medication treatment, care birth newborns, psychological support associated with infection. It is hoped that will effectively help clinical management

Язык: Английский

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COVID-19 pandemic in low-risk pregnant women in 2020-2022: disease confounders and clinical characteristics

Fundamental and Clinical Medicine, Год журнала: 2023, Номер 8(1), С. 32 - 42

Опубликована: Апрель 1, 2023

Aim . To identify confounders and clinical symptoms of COVID-19 in low-risk pregnant women during the pandemics from 2020 to 2022. Materials Methods The study included with COVID-19: 1) those who have been admitted October-December (n = 163); 2) May-August 2021 158); 3) January-February 2022 160). Patients all groups were 3st trimester gestation comparable age (18–35 years), socioeconomic status, parity, body mass index, had no established risk factors for COVID-19. Results Iron deficiency anemia, tobacco smoking, belonging East Asian ethnic group recognized as reliable women. In 1st year pandemic, most common were: loss smell/taste (87.7%), somnolence (68,7%), shortness breath (68.1%). 2nd pandemic year, SARS-CoV-2 Delta variant more frequently resulted fever above 38°C (19.6% vs 7.4%), pneumonia (61.4% 21.4%), respiratory failure (17.7% 4.9%), admission intensive care unit (11.4% 6.4%), invasive mechanical ventilation (1.89% 0). Symptoms 3rd similar observed seasonal acute viral infections: runny nose (66.7%) cough (54.4%), whereas cases rare (3.8%). Conclusion Among without any are iron group. Each provoked vastly different symptoms.

Язык: Английский

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Risk Factors of Adverse Maternal Outcome among SARS-CoV-2 Infected Critically Ill Pregnant Women in Serbia

Journal of Clinical Medicine, Год журнала: 2023, Номер 12(12), С. 3902 - 3902

Опубликована: Июнь 7, 2023

During the COVID-19 pandemic, Serbia has faced devastating losses related to increased mortality rates among men and women of all ages. With 14 registered cases maternal death in 2021, it became obvious that pregnant are with a serious threat jeopardises their life as well unborn child. Studying consequences pandemic on outcomes is vivifying stimulating for many professionals decision-makers, knowing contextual characteristics can facilitate application literature findings practice. Therefore, aim this study was present associated SARS-CoV-2 infected critically ill women. Clinical status pregnancy-related features were analysed series 192 confirmed infection. According treatment outcome, divided two groups: group survivors deceased patients. A lethal outcome recorded seven cases. Pregnant presenting at admission more commonly X-ray-confirmed pneumonia, body temperature >38 °C, cough, dyspnea, fatigue. They likely have progression disease, be admitted intensive care unit, dependent from mechanical ventilation, nosocomial infection, pulmonary embolism, postpartum haemorrhage. On average, they early third trimester pregnancy, gestational hypertension preeclampsia. Initial clinical manifestations such fatigue, fever, could potent factors risk stratification prediction. Prolonged hospitalization, ICU admission, hospital-acquired infections require strict microbiological surveillance should constant reminder rational antibiotics use. Understanding identification poor warn medical potentially unwanted used organising an individualised patient's specific needs, including guide necessary consultations specialists various fields.

Язык: Английский

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Clinical characteristics and confounders of the new coronavirus infection in low-risk pregnant women: an analysis of three years of the pandemic: A cross sectional study

GYNECOLOGY, Год журнала: 2023, Номер 25(2), С. 183 - 188

Опубликована: Июль 14, 2023

Background. During the three years of new coronavirus infection (NCI) pandemic, young women low infectious risk made a certain contribution to severe maternal morbidity and mortality from COVID-19. Aim. To establish factors for give clinical assessment COVID-19 during epidemic outbreaks in 2020, 2021, 2022 low-risk pregnant women. Materials methods. The study included groups with clinically manifested laboratory-confirmed SARS-CoV-2 infection: 163 who became ill first wave October-December 158 second third July October 160 fourth JanuaryFebruary 2022. Each comparison group 100 did not become same periods pandemic. Patients all were III trimester gestation, comparable age (1835 years), social status, parity, body mass index, had no known Results. Iron-deficiency anemia, tobacco smoking, belonging East Asian ethnic showed stable association incidence women. In year pandemic (strains zero Alpha), presentation NCI was dominated by loss smell and/or taste (87.7%), drowsiness (68.7%), dyspnea even mild degree lung damage (68.1%). epidemics (Delta strain) characterized more course disease than year: fever often reported above 38C (19.6% vs 7.4%; p2=0.006), pneumonia confirmed computed tomography (61.4% 21.4%; p20.001), (CT-3: 11.4% 4.9%; p2=0.040; CT-4: 0 6.3%; p20.05), intensive care unit admission (11.4% 6.4%; p2=0.041); there cases invasive mechanical ventilation (1.89% 0; p2=0.118) deaths (0.63% p2=0.492). (Omicron strain), similar seasonal acute respiratory viral predominant symptoms runny nose (66.7%) cough (54.4%); rare (3.8%). Conclusion. Iron deficiency are confounders without factors. Unlike dominant zero, Alpha, Omicron strains, caused Delta strain most course, high rate patients.

Язык: Английский

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What to Expect When Expecting? Experiences of Pregnant Women in Serbia during the COVID-19 Pandemic and State of Emergency

Gender and Research, Год журнала: 2023, Номер 24(1), С. 88 - 113

Опубликована: Сен. 4, 2023

The aim of this paper is to shed light on the experiences non-infected pregnant women in Serbia during COVID-19 pandemic and state emergency by applying a qualitative research method. present analysis examines four aspects being emergency: (a) women's health care; (b) preparation for childbirth arrival new family member; (c) working while pandemic; (d) atmosphere practices. results show that coronavirus affected both psychologically socially. following conditions had negative impact women: worrying about their own baby; significant reduction level quality health-care support; decrease 'external' parental support as result need socially isolate; difficulties managing professional obligations; (e) missing regular pre-pandemic activities; (f) total income changes employment pandemic. Respondents who experienced pregnancy positively high levels marital adjustment stable enjoyed spending more time with husband children

Язык: Английский

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