Patients with Hepatitis C Undergoing Direct-Acting Antiviral Treatment Have a Lower SARS-CoV-2 Infection Rate DOI Creative Commons

Chin‐Wen Hsu,

Wan-Wen Yang,

Chia-Yi Hou

и другие.

Life, Год журнала: 2023, Номер 13(12), С. 2326 - 2326

Опубликована: Дек. 11, 2023

This study retrospectively analyzed the medical records of 602 patients with first-time positive results for HCV nucleic acid test between 1 May 2021 and 31 March 2023, exploring association DAA treatment SARS-CoV-2 infection. The showed that 9.8% were co-infected SARS-CoV-2. Gender, age, vaccination status, genotype did not significantly affect However, undergoing lower rates infection mortality compared to those treatment. analysis also different treatments, Epclusa Maviret showing superior protection against Furthermore, this explored severity in having completed It revealed diagnosed COVID-19 during experienced only mild symptoms, none died, suggesting a potential protective effect severe outcomes findings contribute understanding interplay HCV, treatment, infection, highlighting need continued monitoring healthcare measures individuals chronic conditions ongoing pandemic.

Язык: Английский

COVID-19 vaccinations in patients with chronic liver disease: Correspondence DOI Open Access
Hinpetch Daungsupawong, Viroj Wiwanitkit

Journal of Gastrointestinal and Liver Diseases, Год журнала: 2024, Номер 33(2), С. 281 - 282

Опубликована: Июнь 29, 2024

N/A

Язык: Английский

Процитировано

0
Utility of Escherichia coli Nissle in maintaining disease remission in inflammatory bowel disease DOI Open Access
Osman Çağın Buldukoğlu

Journal of Gastrointestinal and Liver Diseases, Год журнала: 2024, Номер 33(2), С. 280 - 281

Опубликована: Июнь 29, 2024

Gluten does not induce gastrointestinal symptoms in healthy volunteers: the British Broadcasting Company ExperimentTo Editor, While gluten-free diet (GFD) is best treatment for clinical gluten sensitivity (GS) [(e.g.coeliac disease (CD), nonceliac (NCGS)], scientific opinion supports that safe general population [1].However, celebrity/athletic endorsement of GFD has cultivated an image as "unhealthy" [2]."Lifestylers", "free from" or "people who avoid gluten" are individuals a lifestyle choice.American market research [3] found 44% people buy food reasons other than GS, and 65% believe generally healthier.This trend driven worldwide industry from values $1.7bn 2011 to $3.5bn 2016, it forecast reach $4.7bn 2020 [4].The surge popularity also encouraged opposing belief "fad" [2].This unfortunate with CD/NCGS express they taken seriously restaurants, even face dismissive attitudes non-specialist clinicians [5].The drawing clear line between those do benefit needed ground public perspective on these issues.For this reason, conjunction (BBC) we undertook televised experiment.Our hypothesis was giving volunteers (via gluten-containing flour) should cause any symptoms.Participants (who received no financial incentives), recruited by BBC advertising, were ≥18 years, had diagnosed gluten-related disorders followed diets.The experiment aimed recruit 30 subjects divide into two groups; previous data available but NCGS Double Blind Randomised Controlled Trials (DBRCT) have reported symptom changes induced which would carry 89.2% power if observed within group N=15 [6].Participants point care tested (IgA/

Язык: Английский

Процитировано

0
Association between antibody responses post-vaccination and severe COVID-19 outcomes: national population-based cohort study in Scotland DOI Creative Commons
C. M. Macdonald, Norah Palmateer, Andrew McAuley

и другие.

Research Square (Research Square), Год журнала: 2023, Номер unknown

Опубликована: Май 23, 2023

Abstract Several population-level studies have described individual clinical risk factors associated with suboptimal antibody responses following COVID-19 vaccination, but none examined multimorbidity. Others shown that post-vaccination offer reduced protection to subsequent SARS-CoV-2 infection; however, the level of from hospitalisation/death remains unconfirmed. We use national Scottish datasets investigate association between multimorbidity and testing antibody-negative, examining correlation levels among double-vaccinated individuals. found individuals (≥five conditions) were more likely test antibody-negative 13.37 [6.05 - 29.53] times be hospitalised/die than without conditions. also show a dose-dependent hospitalisation or death, those undetectable at significantly higher (HR 9.21 [95% CI 4.63 18.29]) these serious outcomes compared high levels.

Язык: Английский

Процитировано

1
Impact of prior SARS-CoV-2 infection on postoperative recovery in patients with hepatocellular carcinoma resection DOI Creative Commons
Dan Fang,

B.K. Gan,

Lei Wu

и другие.

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Фев. 7, 2024

Abstract BACKGROUND The impact of prior SARS-CoV-2 infection on postoperative recovery patients who underwent liver resection for hepatocellular carcinoma (HCC) remains uncertain given the lack sufficient evidence. AIM To investigate (HCC). METHODS Patients were pathologically diagnosed with HCC and elective partial hepatectomy in Guangdong Provincial People’s Hospital between January 2022 April 2023 enrolled this retrospective cohort study. divided into two groups based their history infection. Rehabilitation parameters, including function, incidence complications, hospitalization expenses, compared groups. Propensity score matching (PSM) was performed to reduce confounding bias. RESULTS We included 172 (58 114 without infection) HCC. No significant differences rehabilitation parameters observed After PSM, 58 selected from each group form new comparative Similar results obtained within population after PSM. CONCLUSION Prior does not appear affect rehabilitation, or expenses among hepatectomy.

Язык: Английский

Процитировано

0
Association between antibody responses post-vaccination and severe COVID-19 outcomes in Scotland DOI Creative Commons
C. M. Macdonald, Norah Palmateer, Andrew McAuley

и другие.

npj Vaccines, Год журнала: 2024, Номер 9(1)

Опубликована: Июнь 14, 2024

Several population-level studies have described individual clinical risk factors associated with suboptimal antibody responses following COVID-19 vaccination, but none examined multimorbidity. Others shown that post-vaccination offer reduced protection to subsequent SARS-CoV-2 infection; however, the level of from hospitalisation/death remains unconfirmed. We use national Scottish datasets investigate association between multimorbidity and testing antibody-negative, examining correlation levels among double-vaccinated individuals. found individuals ( ≥ five conditions) were more likely test antibody-negative 13.37 [6.05-29.53] times be hospitalised/die than without conditions. also show a dose-dependent hospitalisation or death, those undetectable at significantly higher (HR 9.21 [95% CI 4.63-18.29]) these serious outcomes compared high levels.

Язык: Английский

Процитировано

0
Impact of prior SARS-CoV-2 infection on postoperative recovery in patients with hepatocellular carcinoma resection DOI Creative Commons
Dan Fang, Lei Wu,

B.K. Gan

и другие.

BMC Gastroenterology, Год журнала: 2024, Номер 24(1)

Опубликована: Сен. 17, 2024

The impact of prior SARS-CoV-2 infection on postoperative recovery patients who underwent liver resection for hepatocellular carcinoma (HCC) remains uncertain given the lack sufficient evidence.

Язык: Английский

Процитировано

0
Vaccination Strategies for a Liver Transplant Recipient DOI
Monalisa Sahu,

Dibya Lochan Praharaj,

Ajeet Singh Bhadoria

и другие.

Journal of Clinical and Experimental Hepatology, Год журнала: 2024, Номер 15(2), С. 102421 - 102421

Опубликована: Окт. 11, 2024

Язык: Английский

Процитировано

0
The Frequency and Characteristics of Severe Liver-Related Adverse Events in Patients with Chronic Liver Diseases after Vaccination against Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Study DOI Creative Commons

Oyunjargal Bat-Erdene,

Kouichi Miura,

Hiroshi Maeda

и другие.

Gastrointestinal Disorders, Год журнала: 2023, Номер 5(1), С. 15 - 27

Опубликована: Янв. 5, 2023

Background: Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is recommended for patients with chronic liver diseases as the vaccine can prevent and/or reduce severity of SARS-CoV-2 infection. However, we have little information on often-reported liver-related adverse events (LrAEs) caused by mRNA vaccine. Methods: We retrospectively investigated frequency and details LrAEs changes in function tests diseases. Results: Among 431 diseases, 416 (96.5%) had received ≥ times. 345 included analysis, 6 (1.7%) LrAEs; 3 ascites, increases transaminases, 1 an increase total bilirubin. Multivariate analysis demonstrated that cirrhosis autoimmune disease were risk factors LrAEs. In contrast, reserve assessed Child–Pugh ALBI scores did not markedly change after vaccination despite a small transaminase levels. Conclusion: vaccines, which used most our patients, are safe but slightly increased

Язык: Английский

Процитировано

0
Analysis of Differences in User Groups and Post Sentiment of COVID-19 Vaccine Hesitators in Chinese Social-Media Platforms DOI Open Access
Jingfang Liu, Shuangjinhua Lu, Huiqin Zheng

и другие.

Healthcare, Год журнала: 2023, Номер 11(9), С. 1207 - 1207

Опубликована: Апрель 23, 2023

(1) Background: The COVID-19 epidemic is still global and no specific drug has been developed for COVID-19. Vaccination can both prevent infection limit the spread of epidemic. Eliminating hesitation to vaccine achieving early herd immunity a common goal all countries. However, efforts in this area have not significant there long way go eliminate hesitancy. (2) Objective: This study aimed uncover differences characteristics sentiments hesitators on Chinese social-media platforms achieve classification vaccine-hesitant groups. (3) Methods: COVID-19-vaccine-hesitation posts user were collected Sina Microblog platform posting times spanning one year, identified types. Logistic regression was used conduct user-group analysis. between various types analysed according four characteristics: gender, address type, degree personal-information disclosure, whether they followed health topics. Sentiment analysis conducted using sentiment tools calculate scores polarity posts, K-W test posts. (4) Results: There are posted by users with different characteristics, differ terms sentiment. Differences attributes behaviors found across Ultimately, two COVID-19-vaccine-hesitant groups identified: Body-related Non-bodily-related. Users who body-related vaccine-hesitation more often female, disclose personal information follow topics platforms. non-bodily-related male, less information, do average score COVID-19-vaccine-hesitant-type than 0.45, negative-sentiment outweighing positive- neutral-sentiment each among which "Individual rights" type most negative. (5) Conclusions: paper complements application field hesitation, results group post help provide an in-depth comprehensive concerns needs hesitators. will public-health agencies implement targeted strategies hesitancy improve their work related vaccine, far-reaching implications COVID-19-vaccine promotion vaccination.

Язык: Английский

Процитировано

0
COVID-19 vaccine and liver dysfunction DOI Creative Commons
Viroj Wiwanitkit, Sora Yasri, Beuy Joob

и другие.

Gastrointestinal Tract, Год журнала: 2023, Номер 1

Опубликована: Авг. 3, 2023

Due to the COVID-19 pandemic’s high death rate and rapid spread, an effective vaccination is urgently needed. The detrimental consequences of have received a lot attention in reports on vaccine’s side effects. liver problem that appears after getting immunization causes clinical hepatology considerable concern. Hepatitis one issues vaccine may cause. Often, autoimmune pathogenic process mentioned relation pathophysiology. Although precise cause vaccine-related dysfunction not yet understood, immunopathological mechanisms are likely be involved.

Язык: Английский

Процитировано

0