OUTBREAK OF VIRAL HEPATITIS A IN VINNITSYA REGION IN WARTIME PERIOD AMONG PEDIATRIC POPULATION: CLINICAL AND LABORATORY FEATURES DOI Creative Commons
Iryna Nezgoda, О. С. Онофрійчук, Yaroslav Demchyshyn

и другие.

Clinical and Preventive Medicine, Год журнала: 2024, Номер 7, С. 6 - 12

Опубликована: Ноя. 28, 2024

Introduction. HAV is a ubiquitous viral disease with faecal-oral transmission mechanism, characterized by liver lesions. According to global data reposts, the frequency of outbreaks all over world had increased. From beginning outbreak (Vinnytsia, Ukraine) in 2023 incidence rate was detected as 27,25 per 100,000 (in 2022—0,35 100,000). Having analyzed these data, also were registered among pediatric population (88 out 454 cases during outbreak; 19,3%). Incidence and evidence rates increased, especially regions increased military activities, also, facts shown increasing role on burden public health system. Aim. To estimate peculiarities clinical, laboratory features, genotype distribution patients Vinnitsya region 2023–2024 years. Materials methods. Among 88 outbreak, 31 children examined course study formed group (boys—51,6%; average age—12,84±0,16 years). Clinical examination patients, instrumental assays, ELISA, PCR-testing performed accordance standard management. All (n=31; 100%) confirmed ELISA additionally for 16,1% (n=5) examined. Statistical analysis using «SPSS v.22.0». The considered significant at p<0.05. Results. During HAV, 46 serum samples tested PCR genome sequencing 78,2% (n=36) IB while 21,8% (n=10) – IA genotype. (n=5), 80% (n=4) tested, IA—in 20% (n=1). severe 100% (n=31) according indexes. Frequency clinical symptoms group. level total bilirubin, ALT, AST estimated significance. Severe could be explained spreading outbreak. Conclusions. associated HAV. paediatric 80%. main parameters.

Язык: Английский

The burden of infectious diseases throughout and after the COVID‐19 pandemic (2020–2023) and Russo‐Ukrainian war migration DOI
Piotr Rzymski, Dorota Zarębska‐Michaluk, Miłosz Parczewski

и другие.

Journal of Medical Virology, Год журнала: 2024, Номер 96(5)

Опубликована: Май 1, 2024

Understanding how the infectious disease burden was affected throughout COVID-19 pandemic is pivotal to identifying potential hot spots and guiding future mitigation measures. Therefore, our study aimed analyze changes in rate of new cases Poland's most frequent diseases during entire after influx war refugees from Ukraine. We performed a registry-based population-wide Poland 24 2020 2023 compared them prepandemic period (2016-2019). Data were collected publicly archived datasets Epimeld database published by national epidemiological authority institutions. The studied (66.6%) revealed significantly negative correlations with SARS-CoV-2 infections. For majority diseases, it substantially decreased (in case 83%) 2021 (63%), following which mostly rebounded levels and, some cases, exceeded when exceptionally high annual rates scarlet fever, Streptococcus pneumoniae infections, HIV syphilis, gonococcal tick-borne encephalitis noted. Clostridioides difficile enterocolitis two-fold higher than before onward. Legionnaires' also threshold, although this due local outbreak unrelated lifted restrictions or migration refugees. migrants Ukraine could impact epidemiology sexually transmitted diseases. present analysis indicates that continued efforts are needed prevent overwhelming healthcare systems again decreasing control over other It identifies tipping points require additional measures, discussed paper, avoid escalation future.

Язык: Английский

Процитировано

5

Ongoing outbreak of maternal parvovirus B19 infections in Germany since end of 2023: consequence of COVID‐19 pandemic? DOI Creative Commons
J Jiménez Cruz, R Axt-Fliedner, Christoph P. Berg

и другие.

Ultrasound in Obstetrics and Gynecology, Год журнала: 2025, Номер unknown

Опубликована: Март 6, 2025

To investigate the ongoing parvovirus B19 (B19V) outbreak among pregnant women in Germany and its connection to coronavirus disease 2019 (COVID-19) pandemic. This retrospective cohort study analyzed anonymous data regarding serologically confirmed B19V infections during pregnancy between January 2014 April 2024 across 13 major fetal medicine centers Germany. We evaluated yearly frequency of cases, cases that underwent intrauterine transfusion (IUT), presenting with hydrops fetalis death (IUFD) related infection, stratified these variables by event occurrence < 20 weeks' gestation or ≥ gestation. Variables were compared three subperiods: pre COVID-19 pandemic, pandemic post Data from 918 infection revealed a significant since end 2023. The mean ± SD number annual was 57.3 20.7 COVID-19, 20.3 13.5 surged 384.8 299.8 (P 0.01). Correspondingly, which fetus IUT increased COVID-19. proportion diagnoses made before 32.3% 53.2% 0.001). These results demonstrate an unforeseen increase after consequent rise anemia. introduced policies reduced rate but likely conditioned present upsurge. Counseling, early detection access specialized performing are essential measures required address this outbreak. © 2025 Author(s). Ultrasound Obstetrics & Gynecology published John Wiley Sons Ltd on behalf International Society Gynecology.

Язык: Английский

Процитировано

0

Current Massive Parvovirus B19 Outbreak in Germany and the Risk of Intrauterine Infection. A Consequence of the Covid-19 Pandemic? DOI

Jorge Jimenenez Cruz,

Axt-Fliedner Roland,

Christoph Berg

и другие.

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Unveiling the Burden of Hepatitis A in Salerno, Italy: A Comprehensive 9-Year Retrospective Study (2015–2023) on the Seroprevalence of HAV Antibodies and Age/Sex Distribution DOI Open Access
Enrica Serretiello, Domenico Iervolino,

Giuseppe Di Siervi

и другие.

Journal of Clinical Medicine, Год журнала: 2024, Номер 13(18), С. 5534 - 5534

Опубликована: Сен. 18, 2024

Background: Hepatitis A virus (HAV) infection is a significant global cause of viral hepatitis. At present, the anti-HAV vaccine in Italy proposed exclusively for specific high-risk groups, and universal vaccination program not implemented. Objectives: This study aimed to assess level immunity against HAV patients both sexes across age groups ranging from 0 95 years admitted San Giovanni di Dio e Ruggi d’Aragona Hospital Salerno, Italy, over 9-year period (2015–2023). Methods: The total seroprevalence by chemiluminescence Vitros system immunodiagnostics (ortho-diagnostics) was obtained database analysis, stratifying gender group pre-pandemic (2015–2019) pandemic (2020–2023) periods. Results: Out 28,104 samples collected 2015–2023, 20,613 resulted positive immune screening, with reduction annualized proportion events during compared period. more abundant males than females periods (exceeding 70%), statistically decrease 2015–2019. 61–70-year-old susceptible genders, strong deviation 41–50-year-old 51–60-year-old group. affected number analyzed 2020. Conclusions: revealed high seroprevalence, especially individuals aged 61–70 years. There notable These results emphasize need ongoing monitoring suggest that could address regional gaps lower disease incidence.

Язык: Английский

Процитировано

0

OUTBREAK OF VIRAL HEPATITIS A IN VINNITSYA REGION IN WARTIME PERIOD AMONG PEDIATRIC POPULATION: CLINICAL AND LABORATORY FEATURES DOI Creative Commons
Iryna Nezgoda, О. С. Онофрійчук, Yaroslav Demchyshyn

и другие.

Clinical and Preventive Medicine, Год журнала: 2024, Номер 7, С. 6 - 12

Опубликована: Ноя. 28, 2024

Introduction. HAV is a ubiquitous viral disease with faecal-oral transmission mechanism, characterized by liver lesions. According to global data reposts, the frequency of outbreaks all over world had increased. From beginning outbreak (Vinnytsia, Ukraine) in 2023 incidence rate was detected as 27,25 per 100,000 (in 2022—0,35 100,000). Having analyzed these data, also were registered among pediatric population (88 out 454 cases during outbreak; 19,3%). Incidence and evidence rates increased, especially regions increased military activities, also, facts shown increasing role on burden public health system. Aim. To estimate peculiarities clinical, laboratory features, genotype distribution patients Vinnitsya region 2023–2024 years. Materials methods. Among 88 outbreak, 31 children examined course study formed group (boys—51,6%; average age—12,84±0,16 years). Clinical examination patients, instrumental assays, ELISA, PCR-testing performed accordance standard management. All (n=31; 100%) confirmed ELISA additionally for 16,1% (n=5) examined. Statistical analysis using «SPSS v.22.0». The considered significant at p<0.05. Results. During HAV, 46 serum samples tested PCR genome sequencing 78,2% (n=36) IB while 21,8% (n=10) – IA genotype. (n=5), 80% (n=4) tested, IA—in 20% (n=1). severe 100% (n=31) according indexes. Frequency clinical symptoms group. level total bilirubin, ALT, AST estimated significance. Severe could be explained spreading outbreak. Conclusions. associated HAV. paediatric 80%. main parameters.

Язык: Английский

Процитировано

0