The Role of Extracellular Vesicles in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease and Other Liver Diseases DOI Open Access
Elena Grossini, Mohammad Mostafa Ola Pour, Sakthipriyan Venkatesan

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(11), С. 5033 - 5033

Опубликована: Май 23, 2025

The increasing prevalence of liver diseases, such as metabolic dysfunction-associated steatotic disease (MASLD), presents considerable medical challenges, particularly given the absence approved pharmacological treatments, which underscores necessity to comprehend its underlying mechanisms. Extracellular vesicles (EVs), are tiny particles released by cells, play a crucial role in facilitating communication and can transport harmful molecules that promote inflammation tissue damage. These EVs involved progression various types disorders since they aggravate oxidative stress. Because their critical role, it is believed widely initiation MASLD, well viral hepatitis, alcoholic disease, drug-induced injury, hepatocellular carcinoma. This review emphasizes recent findings regarding functions above pathologies potential new therapeutic targets, paving way for innovative approaches address those detrimental conditions.

Язык: Английский

The Role of Extracellular Vesicles in the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease and Other Liver Diseases DOI Open Access
Elena Grossini, Mohammad Mostafa Ola Pour, Sakthipriyan Venkatesan

и другие.

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(11), С. 5033 - 5033

Опубликована: Май 23, 2025

The increasing prevalence of liver diseases, such as metabolic dysfunction-associated steatotic disease (MASLD), presents considerable medical challenges, particularly given the absence approved pharmacological treatments, which underscores necessity to comprehend its underlying mechanisms. Extracellular vesicles (EVs), are tiny particles released by cells, play a crucial role in facilitating communication and can transport harmful molecules that promote inflammation tissue damage. These EVs involved progression various types disorders since they aggravate oxidative stress. Because their critical role, it is believed widely initiation MASLD, well viral hepatitis, alcoholic disease, drug-induced injury, hepatocellular carcinoma. This review emphasizes recent findings regarding functions above pathologies potential new therapeutic targets, paving way for innovative approaches address those detrimental conditions.

Язык: Английский

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