Clostridioides difficile Infections and Antibiotherapy: Results of Four Years of Observation in a Romanian Tertiary Hospital DOI Creative Commons
Carmen-Cristina Vasile,

Liliana Gheorghe,

Carmen-Daniela Chivu

и другие.

Microorganisms, Год журнала: 2024, Номер 12(12), С. 2490 - 2490

Опубликована: Дек. 3, 2024

Clostridioides difficile infection (CDI) is one of the main causes morbidity associated with antibiotic use, producing both healthcare-associated infections and community infections. This study aims to describe epidemiological characteristics, clinical outcomes, previous exposure, other risk factors hospitalized patients CDI in a tertiary infectious disease hospital Bucharest, Romania. We performed descriptive analysis based on four-year surveillance data, collected The annual incidence CDIs varied from 65.1 cases per 10,000 discharges 2020 211.7 2023, continuously ascending trend. Most were hospital-acquired cases. There was high share consumption three months before admission (61.3%). Third-generation cephalosporins, β-lactams inhibitor combination, carbapenems most used antibiotics, shares 46.0%, 25.2%, 18.6%, respectively. Hospitalization 12 contact confirmed case frequent group, occurrences which recorded as 66.2% 2.4%, data identified that trend very variable, suggesting need for continuous multiannual analysis.

Язык: Английский

Clostridioides difficile Infections and Antibiotherapy: Results of Four Years of Observation in a Romanian Tertiary Hospital DOI Creative Commons
Carmen-Cristina Vasile,

Liliana Gheorghe,

Carmen-Daniela Chivu

и другие.

Microorganisms, Год журнала: 2024, Номер 12(12), С. 2490 - 2490

Опубликована: Дек. 3, 2024

Clostridioides difficile infection (CDI) is one of the main causes morbidity associated with antibiotic use, producing both healthcare-associated infections and community infections. This study aims to describe epidemiological characteristics, clinical outcomes, previous exposure, other risk factors hospitalized patients CDI in a tertiary infectious disease hospital Bucharest, Romania. We performed descriptive analysis based on four-year surveillance data, collected The annual incidence CDIs varied from 65.1 cases per 10,000 discharges 2020 211.7 2023, continuously ascending trend. Most were hospital-acquired cases. There was high share consumption three months before admission (61.3%). Third-generation cephalosporins, β-lactams inhibitor combination, carbapenems most used antibiotics, shares 46.0%, 25.2%, 18.6%, respectively. Hospitalization 12 contact confirmed case frequent group, occurrences which recorded as 66.2% 2.4%, data identified that trend very variable, suggesting need for continuous multiannual analysis.

Язык: Английский

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