Advances and Challenges in Antiviral Development for Respiratory Viruses DOI Creative Commons
Luis Adrián De Jesús‐González, Moisés León‐Juárez,

Flor Itzel Lira-Hernández

и другие.

Pathogens, Год журнала: 2024, Номер 14(1), С. 20 - 20

Опубликована: Дек. 31, 2024

The development of antivirals for respiratory viruses has advanced markedly in response to the growing threat pathogens such as Influenzavirus (IAV), syncytial virus (RSV), and SARS-CoV-2. This article reviews advances challenges this field, highlighting therapeutic strategies that target critical stages viral replication cycle, including inhibitors entry, replication, assembly. In addition, innovative approaches inhibiting host cellular proteins reduce resistance repurposing existing drugs are explored, using bioinformatics tools optimize identification antiviral candidates. analysis also covers emerging technologies nanomedicine CRISPR gene editing, which promise improve stability efficacy treatments. While current offer valuable options, they face evolution need accessible treatments vulnerable populations. underscores importance continued innovation biotechnology overcome these limitations provide safe effective Combining traditional developing is essential order address diseases affect global health.

Язык: Английский

Advances and Challenges in Antiviral Development for Respiratory Viruses DOI Creative Commons
Luis Adrián De Jesús‐González, Moisés León‐Juárez,

Flor Itzel Lira-Hernández

и другие.

Pathogens, Год журнала: 2024, Номер 14(1), С. 20 - 20

Опубликована: Дек. 31, 2024

The development of antivirals for respiratory viruses has advanced markedly in response to the growing threat pathogens such as Influenzavirus (IAV), syncytial virus (RSV), and SARS-CoV-2. This article reviews advances challenges this field, highlighting therapeutic strategies that target critical stages viral replication cycle, including inhibitors entry, replication, assembly. In addition, innovative approaches inhibiting host cellular proteins reduce resistance repurposing existing drugs are explored, using bioinformatics tools optimize identification antiviral candidates. analysis also covers emerging technologies nanomedicine CRISPR gene editing, which promise improve stability efficacy treatments. While current offer valuable options, they face evolution need accessible treatments vulnerable populations. underscores importance continued innovation biotechnology overcome these limitations provide safe effective Combining traditional developing is essential order address diseases affect global health.

Язык: Английский

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