Leveraging wastewater-based epidemiology to monitor the spread of neglected tropical diseases in African communities DOI

Benedict Ofori,

Righteous Kwaku Agoha,

Edem Kwame Bokoe

и другие.

Infectious Diseases, Год журнала: 2024, Номер 56(9), С. 697 - 711

Опубликована: Июнь 26, 2024

Neglected tropical diseases continue to cause a significant burden worldwide, with Africa accounting for more than one-third of the global burden. Over past decade, progress has been made in eliminating, controlling, and eradicating these Africa. By December 2022, 47 out 54 African countries had eliminated at least one neglected disease, were close achieving this milestone. Between 2020 2021, there was an 80 million reduction people requiring intervention. However, continued efforts are needed manage address their social economic burden, as they deepen marginalisation stigmatisation. Wastewater-based epidemiology involves analyzing wastewater detect quantify biomarkers disease-causing pathogens. This approach can complement current disease surveillance systems provide additional layer information monitoring spread detecting outbreaks. is particularly important due limited traditional methods. also provides tsunami-like warning system outbreaks facilitate timely intervention optimised resource allocation, providing unbiased reflection community's health compared systems. In review, we highlight potential wastewater-based innovative transmission within communities improving existing Our analysis shows that enhance Africa, early detection management Buruli ulcers, hookworm infections, ascariasis, schistosomiasis, dengue, chikungunya, echinococcosis, rabies, cysticercosis better control.

Язык: Английский

Wastewater-based epidemiology framework: Collaborative modeling for sustainable disease surveillance DOI Creative Commons
Néstor DelaPaz-Ruíz, Ellen-Wien Augustijn, Mahdi Farnaghi

и другие.

The Science of The Total Environment, Год журнала: 2025, Номер 968, С. 178889 - 178889

Опубликована: Фев. 19, 2025

Язык: Английский

Процитировано

1
Wastewater surveillance overcomes socio-economic limitations of laboratory-based surveillance when monitoring disease transmission: The South African experience during the COVID-19 pandemic DOI Creative Commons
Gillian Maree, Fiona Els, Yashena Naidoo

и другие.

PLoS ONE, Год журнала: 2025, Номер 20(2), С. e0311332 - e0311332

Опубликована: Фев. 25, 2025

Wastewater and environmental surveillance has been promoted as a communicable disease tool because it overcomes inherent biases in laboratory-based surveillance. Yet, little empirical evidence exists to support this notion, remains largely an intuitive, though highly plausible hypothesis. Our interdisciplinary study uses WES data show for underreporting of SARS-CoV-2 the context measurable statistically significant associations between economic conditions incidence testing rates. We obtained geolocated, anonymised, laboratory-confirmed cases, wastewater viral load socio-demographic Gauteng Province, South Africa. spatially located all create single dataset sewershed catchments served by two large treatment plants. conducted epidemiological, persons infected principal component analysis explore relationships variables. Overall, we demonstrate co-contributory influences socio-economic indicators on access cumulative incidence, thus reflecting that apparent rates mirror socioeconomic considerations rather than true epidemiology. These analyses how provides valuable information contextualise interpret epidemiological data. Whilst is useful have these established SARS-CoV-2, implications beyond are legion reasons, namely clinical broadly applicable across pathogens infecting humans will find their way into albeit varying quantities. should be implemented strengthen systems, especially where inequalities limit interpretability conventional

Язык: Английский

Процитировано

0
Establishment of Cooperation Between Companies and Institutions in the Baltic Sea region and the World – Reflections from the EcoTech 2024 DOI Open Access
Inga Grīnfelde, Jovita Pilecka-Uļčugačeva

IOP Conference Series Earth and Environmental Science, Год журнала: 2025, Номер 1474(1), С. 011001 - 011001

Опубликована: Апрель 1, 2025

The 14th Annual International Scientific Conference, EcoTech 2024, held in Jelgava, Latvia, marked a significant milestone the history of series, traditionally hosted Sweden. By expanding its geographic scope, conference fostered broader range interdisciplinary collaborations, addressing critical environmental challenges such as climate change, pollution, biodiversity loss, and resource depletion. Featuring diverse array topics, including sustainable agriculture, advanced hydrological modelling, green technologies, circular economy practices, 2024 provided dynamic platform for exchanging groundbreaking research exploring innovative solutions. was further distinguished by emphasis on integrating scientific practical approaches through keynote presentations, interactive sessions, informal networking events. newly designed logo visual identity underscored event’s commitment to sustainability inclusivity, symbolizing interconnectedness regional ecosystems global reach EcoTech’s mission. bringing together academics, policymakers, industry leaders, not only actionable strategies but also strengthened networks across Baltic Sea region beyond. These contributions collectively highlight vital role collaboration achieving equitable future.

Язык: Английский

Процитировано

0
A framework for integrating wastewater-based epidemiology and public health DOI Creative Commons

Hanna Brosky,

Sarah M. Prasek,

Gabriel K. Innes

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Июль 24, 2024

Wastewater-based epidemiology (WBE) is an environmental approach to monitor community health through the analysis of sewage. The COVID-19 pandemic catalyzed scientists and public professionals revisit WBE as a tool optimize resource allocation mitigate disease spread prevent outbreaks. Some studies have highlighted value programs that coordinate with professionals; however, details necessary for implementation are not well-characterized. To respond this knowledge gap, article documents framework successful program in Arizona, titled Wastewater Analysis Tactical Epidemiological Response Systems (WATERS), detailing developed structure methods communication enabled preparedness response actions. This illustrates how operations were employed reduce outbreak severity. outlined here customizable may guide other tool.

Язык: Английский

Процитировано

3
Tracking epidemic viruses in wastewaters DOI Creative Commons
Inés Girón‐Guzmán, Glòria Sánchez, Alba Pérez‐Cataluña

и другие.

Microbial Biotechnology, Год журнала: 2024, Номер 17(10)

Опубликована: Окт. 1, 2024

Classical epidemiology relies on incidence, mortality rates, and clinical data from individual testing, which can be challenging for many countries. Therefore, innovative, flexible, cost-effective, scalable surveillance techniques are needed. Wastewater-based (WBE) has emerged as a highly powerful tool in this regard. WBE analyses substances excreted human fluids faeces that enter the sewer system. This approach provides insights into community health status lifestyle habits. serves an early warning system viral surveillance, detecting emergence of new pathogens, changes incidence identifying future trends, studying outbreaks, informing performance action plans. While long been used to study different viruses such poliovirus norovirus, its implementation surged due pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2. led establishment wastewater programmes at international, national, levels, remain operational. Furthermore, is increasingly applied other including antibiotic resistance bacteria, parasites, fungi, emerging viruses, with methodologies being developed. Consequently, primary focus now creating international frameworks enhance states' preparedness against risks. However, there remains considerable work done, particularly integrating principles One Health epidemiological acknowledge interconnectedness humans, animals, environment pathogen transmission. Thus, broader analysing three pillars must developed, transitioning environmental establishing routine practice public health.

Язык: Английский

Процитировано

3
Leveraging wastewater-based epidemiology to monitor the spread of neglected tropical diseases in African communities DOI

Benedict Ofori,

Righteous Kwaku Agoha,

Edem Kwame Bokoe

и другие.

Infectious Diseases, Год журнала: 2024, Номер 56(9), С. 697 - 711

Опубликована: Июнь 26, 2024

Neglected tropical diseases continue to cause a significant burden worldwide, with Africa accounting for more than one-third of the global burden. Over past decade, progress has been made in eliminating, controlling, and eradicating these Africa. By December 2022, 47 out 54 African countries had eliminated at least one neglected disease, were close achieving this milestone. Between 2020 2021, there was an 80 million reduction people requiring intervention. However, continued efforts are needed manage address their social economic burden, as they deepen marginalisation stigmatisation. Wastewater-based epidemiology involves analyzing wastewater detect quantify biomarkers disease-causing pathogens. This approach can complement current disease surveillance systems provide additional layer information monitoring spread detecting outbreaks. is particularly important due limited traditional methods. also provides tsunami-like warning system outbreaks facilitate timely intervention optimised resource allocation, providing unbiased reflection community's health compared systems. In review, we highlight potential wastewater-based innovative transmission within communities improving existing Our analysis shows that enhance Africa, early detection management Buruli ulcers, hookworm infections, ascariasis, schistosomiasis, dengue, chikungunya, echinococcosis, rabies, cysticercosis better control.

Язык: Английский

Процитировано

0