Metallurgical and Materials Transactions A, Год журнала: 2024, Номер 55(11), С. 4423 - 4444
Опубликована: Авг. 23, 2024
Язык: Английский
BioMedical Engineering OnLine, Год журнала: 2025, Номер 24(1)
Опубликована: Апрель 8, 2025
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
International Journal of Pharmaceutics, Год журнала: 2024, Номер 663, С. 124578 - 124578
Опубликована: Авг. 15, 2024
Язык: Английский
Процитировано
3
Advanced Materials Technologies, Год журнала: 2023, Номер unknown
Опубликована: Дек. 6, 2023
Abstract Creatures in nature perform a variety of activities through adhesion behavior, including moving flexibly and quickly on inclined vertical walls even ceilings. Studying the physical chemical mechanisms underlying their behaviors can provide effective templates for applications such as climbing robots, grippers, medical devices. This review summarizes various major types that creatures rely morphological structures enhance adhesion, addition to discussing inspiration regarding design bionic systems. First, different adopted by natural environments are introduced, theoretical models summarized. Subsequently, convergent evolution exhibited biological is summarized from three perspectives: size limitation, compliance, fluid transport. The development process wherein researchers imitate create artificial adhesives then presented mechanisms: bonding adhesives, fiber arrays, suckers. Fiber arrays further divided into dry wet adhesives. Finally, shortcomings existing systems future trends
Язык: Английский
Процитировано
6
Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12
Опубликована: Май 27, 2024
A developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials targeted cell types, such as cancer cells. In healthcare, has brought about revolutionary changes the treatment various medical and surgical conditions, including orthopedic. Its clinical applications surgery range from instruments suture enhancing imaging techniques, drug delivery, visualization methods, wound healing procedures. Notably, plays a significant role preventing, diagnosing, treating orthopedic disorders, which is crucial for patients’ functional rehabilitation. The integration improves standards patient care, fuels research endeavors, facilitates trials, eventually patient’s quality life. Looking ahead, holds promise achieving sustained success numerous disciplines, surgery, years come. This review aims focus on application highlighting recent development future perspective bridge translation.
Язык: Английский
Процитировано
1
Polymers, Год журнала: 2024, Номер 16(13), С. 1895 - 1895
Опубликована: Июль 2, 2024
The current paper highlights the active development of tissue engineering in field biofabrication living analogues through 3D-bioprinting technology. implementation latter is impossible without important products such as bioinks and their basic components, namely, hydrogels. In this regard, engineers are searching for biomaterials to produce hydrogels with specified properties both terms physical, mechanical chemical local biological effects following implantation into an organism. One provision optimal conditions physiological reparative regeneration by structural components that form basis biomaterial. Therefore, qualitative assessment composition protein component a biomaterial significant task bioprinting. It predicting behaviour printed constructs gradual resorption followed due formation new extracellular matrix. most promising natural potential production based on them polymer collagen allogeneic origin, which plays role maintaining integrity matrix, well morphogenesis cellular metabolism tissues, giving required biochemical properties. engineering, widely used because its availability, biocompatibility facile combination other materials. This manuscript presents main results mass spectrometry analysis (proteomic assay) lyophilized hydrogel produced from registered Lyoplast® bioimplant (allogeneic human bone tissue), biotechnology. Proteomic assays investigated sample showed presence proteins (six major fibers types I, II, IV, IX, XXVII, XXVIII were identified), matrix proteins, mRNA-stabilizing participate regulation transcription, inducer mediate activation regeneration, including level circadian rhythm. research offer perspective indicate effective alternative synthetic xenogeneic materials regenerative medicine, particularly biotechnology, acting cell-containing 3D
Язык: Английский
Процитировано
1
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 279, С. 135018 - 135018
Опубликована: Авг. 28, 2024
Язык: Английский
Процитировано
1
Fundamental Research, Год журнала: 2024, Номер unknown
Опубликована: Фев. 1, 2024
The bone repair niche, including the physiological and pathological microenvironment, is a complex system that interferes with various cellular/noncellular activities. Thus, rational perspective of designing tunable biomaterials modulation microenvironment in high demand pre/clinical practice for management refractory defects combination severe diseases. Two-dimensional (2D) layered materials are emerging engineering because their inherent biocompatibility, osteo-inductivity, osteo-conductivity, optical properties, enzyme mimetics, mechanical properties. In this study, we focus on latest advances developing 2D regeneration, cancer therapies, bone-related infections eradication, articular cartilage repair. addition, specific action mechanisms design regimens 2D-layered material-based nanoplatforms clarified. Finally, current challenges discussed, key inspirations further broadening applications orthopedic disorder therapy proposed.
Язык: Английский
Процитировано
0
Biomaterials Science, Год журнала: 2024, Номер 12(12), С. 3193 - 3201
Опубликована: Янв. 1, 2024
Considering the shortcomings of known medical hemostatic materials such as bone wax for bleeding management, it is essential to develop alternative capable efficient hemostasis and regeneration adaptable clinical surgical needs. Thus, in current work, a calcium sulfate hemihydrate starch-based composite paste was developed optimized. Firstly, found that use hydroxypropyl distarch phosphate (HDP) coupled with pregelatinization could generate an injectable, malleable self-hardening impressive anti-collapse ability dynamic aqueous environment, suggesting its potential applicability both open minimally invasive practice. The as-hardened matrix exhibited compressive strength up 61.68 ± 5.13 MPa compared cement 15.16 2.42 MPa, making promising candidate temporary mechanical stabilization defects. Secondly, as-prepared revealed superior regenerative capabilities wax, greatly enhanced management healing outcomes when subjected testing vitro vivo models. In summary, our results confirmed reinforced selected starch can act reliable platform treatment, overcoming limitations traditional agents.
Язык: Английский
Процитировано
0
Journal of Applied Polymer Science, Год журнала: 2024, Номер 141(38)
Опубликована: Июль 8, 2024
Abstract The increase in bone fractures has been driving the development of materials for repair with better mechanical and biological properties. This work reports poly (lactic acid) (PLA)‐zinc oxide (ZnO) biocomposites 3D printing scaffolds to be applied tissue engineering. ZnO surface was functionalized maleic anhydride (ZnOMA) by applying radio frequency plasma treatment as an alternative control catalytic effects on degradation PLA during molten state processing. ZnOMA powders were processed using a heated internal mixer resulted used manufacture printing. characterized their rheological, thermal, microstructural, mechanical, Compositions containing presented higher viscosities, evidencing functionalization, achieved elastic modulus near 1 GPa, suitable applications, unlike untreated samples. In relation cell functions, PLA‐ZnOMA exhibited viabilities at 160%, compared 50% samples stimulated mesenchymal stem cells toward osteoblast. Therefore, ZnO's negative thermal effect successfully overcome enabling bioactive great potential application
Язык: Английский
Процитировано
0