Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Апрель 23, 2025
Diabetic
Retinopathy
(DR)
is
a
leading
cause
of
vision
impairment
globally,
necessitating
regular
screenings
to
prevent
its
progression
severe
stages.
Manual
diagnosis
labor-intensive
and
prone
inaccuracies,
highlighting
the
need
for
automated,
accurate
detection
methods.
This
study
proposes
novel
approach
early
DR
by
integrating
advanced
machine
learning
techniques.
The
proposed
system
employs
three-phase
methodology:
initial
image
preprocessing,
blood
vessel
segmentation
using
Hopfield
Neural
Network
(HNN),
feature
extraction
through
an
Attention
Mechanism-based
Capsule
(AM-CapsuleNet).
features
are
optimized
Taylor-based
African
Vulture
Optimization
Algorithm
(AVOA)
classified
Bilinear
Convolutional
(BCAN).
To
enhance
classification
accuracy,
introduces
hybrid
Electric
Fish
Arithmetic
(EFAOA),
which
refines
exploration
phase,
ensuring
rapid
convergence.
model
was
evaluated
on
balanced
dataset
from
APTOS
2019
Blindness
Detection
challenge,
demonstrating
superior
performance
in
terms
accuracy
efficiency.
offers
robust
solution
DR,
potentially
improving
patient
outcomes
timely
precise
diagnosis.
Biomimetics,
Год журнала:
2025,
Номер
10(2), С. 88 - 88
Опубликована: Фев. 1, 2025
This
research
paper
explores
the
development
of
AI-optimized
lattice
structures
for
biomechanics
scaffold
design,
aiming
to
enhance
bone
implant
functionality
by
utilizing
advanced
human–AI
systems.
The
primary
objective
is
create
that
mimic
mechanical
properties
natural
and
improve
bioactivity
biocompatibility,
adapting
patient-specific
needs.
We
employed
polylactic
acid
(PLA),
calcium
hydroxyapatite
(cHAP),
reduced
graphene
oxide
(rGO)
as
base
materials,
leveraging
their
synergistic
properties.
scaffolds
were
intricately
designed
using
nTopology
software
(nTop
5.12)
fabricated
via
3D
printing
techniques,
optimizing
biomechanical
load-bearing
cellular
integration.
study’s
findings
highlight
a
notable
enhancement
in
scaffolds,
with
Gyroid
design
demonstrating
20%
higher
energy-absorption
capacity
than
traditional
designs.
Thermal
chemical
analysis
revealed
15%
increase
thermal
stability
composites,
enhancing
resilience
under
physiological
conditions.
However,
identified
minor
inconsistencies
filament
diameter
during
printing,
which
could
affect
uniformity.
These
underscore
potential
integrating
AI-driven
material
composites
revolutionizing
orthopedic
technologies.
BMC Cardiovascular Disorders,
Год журнала:
2025,
Номер
25(1)
Опубликована: Фев. 20, 2025
Alignment
of
advanced
cutting-edge
technologies
such
as
Artificial
Intelligence
(AI)
has
emerged
a
significant
driving
force
to
achieve
greater
precision
and
timeliness
in
identifying
cardiovascular
diseases
(CVDs).
However,
it
is
difficult
high
accuracy
reliability
CVD
diagnostics
due
complex
clinical
data
the
selection
modeling
process
useful
features.
Therefore,
this
paper
studies
AI-based
feature
techniques
application
AI
classification.
It
uses
methodologies
Chi-square,
Info
Gain,
Forward
Selection,
Backward
Elimination
an
essence
health
indicators
into
refined
eight-feature
subset.
This
study
emphasizes
ethical
considerations,
including
transparency,
interpretability,
bias
mitigation.
achieved
by
employing
unbiased
datasets,
fair
techniques,
rigorous
validation
metrics
ensure
fairness
trustworthiness
diagnostic
process.
In
addition,
integration
various
Machine
Learning
(ML)
models,
encompassing
Random
Forest
(RF),
XGBoost,
Decision
Trees
(DT),
Logistic
Regression
(LR),
facilitates
comprehensive
exploration
predictive
performance.
Among
diverse
range
XGBoost
stands
out
top
performer,
achieving
exceptional
scores
with
99%
rate,
100%
recall,
F1-measure,
precision.
Furthermore,
we
venture
dimensionality
reduction,
applying
Principal
Component
Analysis
(PCA)
subset,
effectively
refining
compact
six-attribute
Once
again,
shines
model
choice,
yielding
outstanding
results.
achieves
accuracy,
98%,
100%,
97%,
respectively,
when
applied
subset
derived
from
combination
Chi-square
Selection
methods.
Sensors,
Год журнала:
2025,
Номер
25(6), С. 1812 - 1812
Опубликована: Март 14, 2025
The
need
for
creative
solutions
in
the
real-time
monitoring
of
health
is
rapidly
increasing,
especially
light
incidents
relation
to
drivers
motor
vehicles.
A
sensor-based
system
provides
an
integrated
mechanism
diagnosing
and
managing
real
time,
enabling
detection,
prediction,
recommendation
treatment
prevention
disease
onset.
driver’s
represents
a
significant
advancement
assurance
driver
safety
well-being.
From
fitness
trackers
advanced
biosensors,
these
devices
have
not
only
made
healthcare
more
accessible
but
also
transformed
how
people
interact
with
their
data.
purpose
this
scoping
review
systematically
collect
evaluate
information
from
publications
on
systems
provide
comprehensive
overview
current
state
research
wearable
or
remote
sensor
technologies
monitoring.
It
aims
identify
knowledge
gaps
that
be
addressed
suggest
future
directions
will
help
fill
gaps.
This
approach
involves
topic
vehicle
contribute
field.
By
focusing
parameters
automotive
context,
highlights
potential
different
types
bridge
gap
between
safety.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Март 26, 2025
Inadequate
sleep
has
been
associated
with
an
increased
risk
of
mortality
and
various
health
issues.
We
previously
conducted
a
placebo-controlled
vaccination
trial
healthy
adults
who
were
monitored
by
blood
samples,
questionnaires,
wearable
devices.
C-reactive
protein
(CRP),
systemic
marker
inflammation,
linked
to
numerous
outcomes,
was
found
significantly
increase
post-vaccination
in
the
trial.
In
this
retrospective
study,
we
investigated
that
if
inflammation
response
triggered
perturbations
from
vaccine
placebo
injections.
Plasma
hs-CRP
levels
measured
on
same
day
as
intervention,
prior
vaccine/placebo
administration
two
days
after
intervention.
Associations
duration
CRP
188
participants
regression
models
adjusting
for
age,
sex,
body
mass
index
(BMI),
comorbidities,
status
(vaccination
or
placebo),
averaged
daily
steps.
shorter
wearable-derived
Total
Sleep
Time
(TST)
Bed
(TIB),
well
subjectively
assessed
Pittsburgh
Quality
Index
(PSQI),
independently
higher
incidence
elevation
administration.
Our
study
suggests
deprivation
could
be
predictor
inflammatory
highlights
potential
application
metrics
public
health.
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2025,
Номер
13
Опубликована: Март 27, 2025
The
search
for
suitable
manufacturing
methods
and
the
selection
of
biocompatible
material
with
good
mechanical
properties
is
still
a
major
challenge
in
implant
development.
polyethylene
terephthalate
glycol
(PETG)
thermoplastic
extensively
utilized
biomedical
applications,
like
tissue
engineering,
dental,
scaffolds
surgery,
because
its
biocompatibility.
Fused
deposition
modeling
(FDM)
gaining
importance
wide
range
applications
developing
custom
shaped
medical
implants.
This
study
aimed
to
fabricate
cranial
using
optimized
parameters
3D
printed
PETG
properties.
research
investigates
optimization
key
printing
layer
height,
line
width
print
speed
by
utilizing
Box
Behnken
Design
(BBD).
Analysis
suggests
that
influential
FDM
are
height
width,
which
significantly
influence
tensile
compressive
strength.
analysis
variance
(ANOVA)
showed
0.12
mm,
0.77
mm
25.75
mm/s
indicated
increased
value
strength,
i.e.,
51.18
MPa
52.33
MPa,
respectively.
effectiveness
RSM
model
was
confirmed
validation
experiment,
errors
less
than
2%.
Additionally,
this
presents
process
framework
development
customized
implants
computed
tomography
(CT)
scan
data
patient.
tested
under
uniaxial
load
shows
an
average
peak
1088
N.
goal
assist
surgeons
overcoming
clinical
challenges
faced
while
selecting
materials
in-house
production
patient-specific
A
further
evaluation
presented
technology
recommended
potential
use
trials.