Assessment of vaccinations and breakthrough infections after adjustment of the dynamic zero-COVID-19 strategy in China: an online survey
Emerging Microbes & Infections,
Год журнала:
2023,
Номер
12(2)
Опубликована: Сен. 11, 2023
Coronavirus
disease
2019
(COVID-19)
cases
in
China
has
grown
rapidly
after
adjustment
of
the
dynamic
zero-COVID-19
strategy.
However,
how
different
vaccination
states
affect
symptoms,
severity
and
post
COVID
conditions
was
unclear.
Here,
we
used
an
online
questionnaire
to
investigate
infection
status
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
among
11,897
participants,
with
55.55%
positive
28.42%
negative.
The
common
COVID-19
symptoms
were
fatigue
(73.31%),
cough
(70.02%),
fever
(65.25%)
overall
soreness
(58.64%);
self-reported
asymptomatic
accounted
for
0.7%
participants.
persistent
at
1
month
included
(48.7%),
drowsiness
(34.3%),
(30.1%),
decreased
exercise
ability
(23.1%)
pharyngeal
discomfort
(19.4%),
which
reduced
by
more
than
200%
months.
Participants
complications
such
as
chronic
obstructive
pulmonary
disease,
diseases,
diabetes,
hypertension,
etc.
have
a
higher
proportion
hospitalization
longer
recovery
time
(
Язык: Английский
The impact of risk perception and institutional trust on COVID-19 vaccine hesitancy in China
Human Vaccines & Immunotherapeutics,
Год журнала:
2024,
Номер
20(1)
Опубликована: Янв. 28, 2024
Vaccination
has
become
the
primary
means
for
citizens
to
prevent
severe
morbidity
and
mortality
during
pandemic.
However,
vaccine
hesitancy
poses
a
major
threat
global
public
health
security.
Based
on
data
from
Chinese
General
Social
Survey
in
2021,
this
study
aims
explore
socio-political
aspects
of
COVID-19
hesitancy,
focusing
relationship
between
risk
perceptions,
institutional
trust
hesitancy.
Among
samples,
39.8%
respondents
exhibited
48.9%
had
high
awareness
COVID-19,
74.6%
presented
level
institutions.
The
results
showed
that
higher
perception
are
negatively
correlated
with
(p
<
.001).
Institutional
no
statistically
significant
moderating
effect
association
but
role
influencing
is
more
at
lower
perceptions
risk.
Furthermore,
regional
variations
factors
contributing
were
demonstrated
China.
These
findings
have
important
implications
developing
strategies
address
Язык: Английский
Azvudine for the Treatment of COVID‐19 in Pre‐Existing Cardiovascular Diseases: A Single‐Center, Real‐World Experience
Advanced Science,
Год журнала:
2024,
Номер
11(23)
Опубликована: Март 27, 2024
Abstract
COVID‐19
can
lead
to
adverse
outcomes
in
patients
with
pre‐existing
diseases.
Azvudine
has
been
approved
for
treating
China,
but
the
real‐world
data
is
limited.
It
aimed
investigate
efficacy
of
and
cardiovascular
Patients
confirmed
diseases
are
retrospectively
enrolled.
The
primary
outcome
all‐cause
death
during
hospitalization.
Overall,
351
included,
a
median
age
74
years,
44%
female.
212
(60.6%)
severe
cases.
used
106
(30.2%)
not
245
(69.8%).
72
died
After
multivariate
adjustment,
who
received
lower
risk
(hazard
ratio:
0.431;
95%
confidence
interval:
0.252–0.738;
p
=
0.002)
than
controls.
therapy
also
associated
risks
shock
acute
kidney
injury.
For
sensitivity
analysis
propensity
score‐matched
cohort
(
n
90
each
group),
there
significant
difference
between
two
groups
0.189;
0.071–0.498;
<
0.001).
This
study
indicated
that
better
Язык: Английский
Lactating nurses' experiences of return to work after lifting COVID-19 lockdown: A qualitative study
Heliyon,
Год журнала:
2023,
Номер
10(1), С. e23761 - e23761
Опубликована: Дек. 24, 2023
AimTo
explore
the
lactating
nurses'
experiences
of
return
to
work
after
lifting
COVID-19
lockdown.BackgroundReturn
is
a
key
reason
for
low
rates
breastfeeding.
Especially
lockdown,
case
counts
reached
recorded
highs.
So
nurses
face
more
challenges
when
they
work.MethodThe
empirical
phenomenology
method
was
used
conduct
qualitative
study.
Lactating
were
recruited
in
tertiary
hospital
through
purposive
and
snowball
sampling,
participated
semi-structured
video
interviews.
Colaizzi's
analyze
data.ResultsThree
themes
10
sub-themes
emerged
from
interview
data
15
participants.
The
first
theme
"preparation
work",
which
helped
adapt
quickly.
second
"experiences
work".
inconvenience
pumping
mentioned
repeatedly.
In
addition,
flexible
schedule
highlighted.
third
infection".
attitudes
toward
breastfeeding
differed
due
different
perceptions
COVID-19.ConclusionsLactation
easily
interrupted
or
stopped
returned
lockdown.
Recommendations
include
further
provision
longer
periods
leave,
working
arrangements,
separate
facilities
breast
pumping,
strategies
epidemics.
Язык: Английский
Investigating the association between perceived risk levels and commuting mode shifts after the lifting of the COVID-19 pandemic prevention and control policies
Transportation Research Interdisciplinary Perspectives,
Год журнала:
2024,
Номер
25, С. 101085 - 101085
Опубликована: Май 1, 2024
There
is
a
research
gap
in
understanding
people's
perceived
risks
and
their
commute
mode
shifts
after
the
major
shift
anti-pandemic
policies.
Our
study
aims
to
reveal
relationship
between
commuters'
commuting
transfers
specific
context
of
canceling
We
conducted
an
online
sample
survey
residents
6
neighborhoods
one
month
lifting
policies
Kunming,
China.
Measured
risk
data
suggested
that
score
23
∼
30
accounted
for
62
%
respondents,
who
were
defined
as
high-perceived
group;
while
14
22
36
middle-perceived
only
2
respondents
with
14.
Commuting
transfer
statistics
showed
22.2
switched
from
other
modes
private
cars,
which
56.1
came
public
transportation.
Conversely,
out
81
car
commuters,
3
moved
modes.
used
nonparametric
tests
find
there
group
differences
shifts.
Specifically,
proportion
commuters
levels
shifted
travel
cars
was
11%
larger
than
levels.
Public
more
likely
switch
active
commuters.
The
test
results
also
single
variables
such
ownership,
distance,
age,
marital
status
significantly
correlated
distribution
shifting
mode.
Furthermore,
we
employed
binary
logistic
regression
model
higher
levels,
longer
distances,
or
ownership
conclusion
this
COVID-19
pandemic
prevention
control
increases
level
pushes
them
commuting.
It
necessary
pre-estimating
level,
pre-judging
changes
daily
behaviors
before
deciding
cancel
Язык: Английский
Clinical Characteristics of Diabetic Patients with COVID-19 During the Full Liberalization of the Pandemic
Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Май 24, 2024
Abstract
Diabetes
is
an
important
comorbidity
of
COVID-19.
This
study
aimed
to
compare
the
clinical
course
and
outcomes
COVID-19
patients
with
without
diabetes.
We
enrolled
321
hospitalized
from
Third
Xiangya
Hospital
(Hunan,
China)
between
December
20,
2021,
March
1,
including
158
diabetes
163
Data
medical
records,
characteristics,
coexisting
conditions,
complications,
laboratory
tests,
radiographic
studies,
treatments
outcomes,
were
extracted
analyzed.
Among
type
2
diabetes,
several
biochemical
parameters,
such
as
systolic
blood
pressure
[137.00
(IQR:
122.00-148.50)
vs.
126.00
116.00-137.00),
P<0.001],
CRP
[64.25
28.16-129.83)
44.13
17.56-87.26),
P
=
0.005],
PCT
[0.11
0.06-0.44)
0.08
(IQR
:
0.05-0.14),
0.002],
urea
nitrogen
[15.40
10.62-24.44)
10.34
(IQR:7.56-15.14),
<
0.001),
In
terms
symptoms,
had
pleural
effusion
[17.3%
7.5%,
P=0.010],
fever
[39.0%
60.7%,
nausea
vomiting
[10.4%
1.2%,
fatigue
symptoms
[22.7%
vs
12.9%,
P=0.022].
There
significant
differences
in
comorbidities,
hypertension
(71.2%
37.0%,
P<0.001)
chronic
kidney
disease
(6.4%
18.5%,
P=0.001).
The
statistically
difference
treatment
those
was
mainly
reflected
use
azvudine
(15.9%
40.7%,
P<0.001).
Regression
analysis
revealed
that
lymphocyte
ratio
(0R=0.925,
95%
CI
0.885-0.966,
age
(0R=1.025,
1.003-1.048,
P=0.027)
a
effect
on
severity
respiratory
failure.
Some
medication
effects
survival
time,
calcification
(HR=0.410,
0.193-0.872,
P=0.021),
(HR=1.935,
1.259-2.975,
P=0.003),
(HR=1.416,
1.042-1.926,
P=0.026),
(HR=1.557,
1.032-2.349,
P=0.035),
antibiotics
(HR=1.623,
1.139-2.315,
P=0.007)
glucocorticoids
P=0.005),
mechanical
ventilation
(HR=4.201,
1.883-9.377,
Our
suggested
tend
have
more
severe
poorer
this
relationship
requires
further
exploration.Retrospectively
registered.
Язык: Английский
WITHDRAWN: Clinical Characteristics of Diabetic Patients with COVID-19 During the Full Liberalization of the Pandemic
Research Square (Research Square),
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 17, 2024
Abstract
The
full
text
of
this
preprint
has
been
withdrawn
by
the
authors
in
order
to
comply
with
an
institutional
policy
on
preprints.
Therefore,
do
not
wish
work
be
cited
as
a
reference.
Язык: Английский
What are the frequent complaints voiced by inpatients and physicians amidst the emerging infectious diseases? — An illustrative instance of the COVID-19
BMC Infectious Diseases,
Год журнала:
2024,
Номер
24(1)
Опубликована: Авг. 7, 2024
Emerging
infectious
diseases
(EIDs)
can
disrupt
the
healthcare
system,
causing
regulatory
changes
that
affect
healthcare-seeking
process
and
potentially
increase
patient-physician
dissatisfaction.
This
study
aimed
to
collect
analyze
patients'
physicians'
complaints
during
an
EID
outbreak
inform
potential
clues
regarding
medical
quality
patient
safety
enhancement
in
future
dealing
with
EIDs,
employing
text
mining
methodologies.
Язык: Английский
Safety, immunogenicity and immune-persistence of heterologous prime-boost immunization with BBIBP-CorV and ZF2001 against SARS-CoV-2 in healthy adults aged 18 years or older
Expert Review of Vaccines,
Год журнала:
2023,
Номер
22(1), С. 1079 - 1090
Опубликована: Окт. 25, 2023
Because
SARS-CoV-2
mutations
and
immunity
wane
over
time,
a
third
dose
of
heterologous
COVID-19
vaccine
is
proposed
for
individuals
primed
with
inactivated
vaccine.We
conducted
single-center,
open-label
trial
to
assess
the
safety,
immunogenicity,
immune-persistence
BBIBP-CorV/ZF2001
prime-boost
vaccination
in
Chinese
adults.
480
participants
who
had
been
two
doses
BBIBP-CorV,
received
ZF2001
after
an
interval
3-4,
5-6,
or
7-9
months.The
overall
incidence
adverse
reactions
within
30
days
was
5.83%.
No
serious
were
reported.
The
respective
geometric
mean
titers
(GMTs)
neutralizing
antibodies
months
groups
at
baseline
2.06,
2.02,
2.10;
which
increased
55.42,
63.45,
62.06
on
day
14;
then
decreased
17.53,
23.79,
26.73
30;
before
finally
waning
8.29,
9.24,
9.51
180.
After
booster,
three
showed
no
significant
differences
GMTs.
GMTs
lower
older
than
younger
participants.A
safe
immunogenic.
Prime-boost
intervals
did
not
affect
immune
response.
response
weaker
adults
adults.NCT05205083.
Язык: Английский