A state-of-the-art review of the recent advances in exosome isolation and detection methods in viral infection
Virology Journal,
Год журнала:
2024,
Номер
21(1)
Опубликована: Янв. 30, 2024
Abstract
Proteins,
RNA,
DNA,
lipids,
and
carbohydrates
are
only
some
of
the
molecular
components
found
in
exosomes
released
by
tumor
cells.
They
play
an
essential
role
healthy
diseased
cells
as
messengers
short-
long-distance
intercellular
communication.
However,
since
every
kind
cell
may
be
blood
other
bodily
fluids,
they
one
day
serve
biomarkers
for
a
wide
range
disorders.
In
many
pathological
conditions,
including
cancer,
inflammation,
infection,
role.
It
has
been
shown
that
biogenesis
is
analogous
to
viruses
exosomal
cargo
plays
propagation,
dissemination,
infection
several
viruses.
Bidirectional
modulation
immune
response
achieved
ability
associated
with
facilitate
immunological
escape
stimulate
body's
antiviral
response.
Recently,
have
received
lot
interest
due
their
potential
therapeutic
use
viral
infections
such
human
immunodeficiency
virus
(HIV),
Hepatitis
B
(HBV),
C
(HCV),
Epstein–Barr
(EBV),
SARS-CoV-2.
This
article
discusses
purification
procedures
detection
techniques
examines
research
on
biomarker
infection.
Graphical
abstract
Язык: Английский
Exosomes and SARS-CoV-2 infection
Frontiers in Immunology,
Год журнала:
2024,
Номер
15
Опубликована: Ноя. 26, 2024
Exosomes,
which
are
small
extracellular
vesicles,
of
particular
interest
in
studies
on
SARS-CoV-2
infection
because
their
crucial
role
intercellular
communication.
These
vesicles
released
by
several
cell
types
and
rich
"cargo"
such
as
proteins,
lipids,
nucleic
acids,
vital
for
regulating
immune
response
viral
pathogenesis.
Exosomes
have
been
reported
to
be
involved
transmission,
escape
mechanisms,
illness
development
infection.
This
review
examines
the
current
research
contribution
exosomes
interplay
between
virus
host
cells,
highlighting
potential
diagnostic
biomarkers
therapeutic
targets
combating
COVID-19.
Язык: Английский