Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review
Biomedicines,
Год журнала:
2025,
Номер
13(1), С. 182 - 182
Опубликована: Янв. 13, 2025
Background/Objectives:
The
gold
standard
in
the
non-surgical
treatment
of
periodontitis
is
scaling
and
root
planning
(SRP).
In
recent
years,
studies
have
emerged
suggesting
additional
clinical
benefits
from
use
statins
as
an
adjunct
to
classical
periodontal
disease
treatment.
aim
present
study
was
review
relevant
literature
relating
subgingival
adjunctive
classical,
periodontitis,
with
a
particular
focus
on
groups
general
factors
that
may
affect
outcome
Methods:
authors
conducted
systematic
following
PRISMA
2020
guidelines.
electronic
search
included
MEDLINE
(PubMed)
database,
Web
Science,
Scopus,
Google
Scholar
1
January
2012
14
June
2024.
keywords
used
for
PubMed
were
determined
help
MeSH
Browser
Tool
follows:
Periodontitis
[Mesh]
AND
Statin
OR
Simvastatin
Atorvastatin
or
Rosuvastatin
Calcium
[Mesh].
Based
authors’
inclusion
exclusion
criteria,
20
results
review,
out
937.
Results:
improvement
more
pronounced
patients
without
diseases
compared
those
type
II
diabetes
non-smokers
smoking
patients.
Greater
improvements
radiological
parameters
seen
diagnosed
aggressive
chronic
periodontitis.
Conclusions:
This
led
conclusion
applied
locally
might
be
competent
agents
improving
therapeutic
outcomes
SRP.
Язык: Английский
Evaluation of Morphology and Biochemical Parameters of Young Adults Using Heated Tobacco Products in Poland: A Case-Control Study
Journal of Clinical Medicine,
Год журнала:
2025,
Номер
14(8), С. 2734 - 2734
Опубликована: Апрель 16, 2025
Background/Objectives:
Little
is
currently
known
of
the
impact
heated
tobacco
on
health.
The
aim
this
study
to
evaluate
use
selected
health
assessment
parameters
among
people
aged
18–30
determine
effect
status.
Methods:
A
case-control
was
conducted
from
April
2022
February
2025.
total
195
young,
healthy
adult
residents
Lodz,
Poland,
took
part.
participants
were
divided
into
three
groups:
IQOS
(I-Quit-Ordinary-Smoking)
smokers
who
had
never
smoked
or
quit
smoking
six
months
previously
(n
=
65);
daily
at
least
five
cigarettes
per
day
for
one
year
and
not
used
any
other
substitutes
have
products
65).
Blood
samples
37
users
(57%),
28
traditional
cigarette
(43%),
45
non-smokers
(69%)
submitted
laboratory
analysis.
tested
determined
in
diagnostic
Bonifratów
Hospital
Lodz.
Results:
No
significant
differences
(p
>
0.05)
found
between
groups
with
regard
blood
count
(white
cell
(WBC),
red
(RBC),
lymphocytes,
monocyte
number
(MONO),
hemoglobin
concentration
(HGB)),
biochemical
biomarkers
(C-reactive
protein
(CRP),
fibrinogen,
apolipoprotein
A1
(apo
A1),
B
B),
glucose),
lipid
profile
(total
cholesterol,
triglycerides
(TG),
high-density
lipoprotein
(HDL),
low-density
(LDL)).
demonstrated
significantly
higher
uric
acid
levels
compared
non-smokers:
5.22
vs.
4.77
4.40
mg/dL
<
0.01).
platelet
290.27
267.14
256.33
×
103/
μL
0.05).
Among
37),
level
glucose
(ρ
−0.47;
p
0.01),
WBC
−0.36;
0.03),
lymphocytes
−0.38;
0.02),
−0.34;
0.04)
negatively
correlated
sticks.
HDL
positively
0.39;
0.02)
Conclusions:
Further
cohort
studies
assessing
status
young
nicotine
prospective
analyses
are
necessary.
Язык: Английский
The Use of Hyaluronic Acid in the Non-Surgical Treatment of Periodontitis—An Umbrella Review
Biomedicines,
Год журнала:
2025,
Номер
13(4), С. 998 - 998
Опубликована: Апрель 20, 2025
Background:
Periodontitis
is
a
prevalent
inflammatory
condition
that
destroys
periodontal
tissues.
Scaling
and
root
planing
(SRP)
the
gold
standard
for
non-surgical
treatment;
however,
its
efficacy
may
be
limited
in
cases
with
complex
dental
issues.
This
umbrella
review
aims
to
evaluate
effectiveness
of
hyaluronic
acid
(HA)
as
an
adjunct
scaling
enhancing
clinical
outcomes
periodontitis
management.
Methods:
A
comprehensive
five
systematic
reviews,
including
meta-analyses
where
available,
was
conducted
synthesize
evidence
on
adjunctive
use
HA
SRP.
The
studies
were
evaluated
using
AMSTAR-2
quality
assessment
tool
determine
methodological
rigor.
Data
parameters
such
probing
depth
(PD),
attachment
level
(CAL),
bleeding
(BOP),
gingival
index
(GI),
plaque
(PI)
extracted
analyzed.
Results:
findings
indicate
supplementation
leads
moderate
improvements
PD,
CAL,
BOP,
GI,
PI
compared
SRP
alone.
Notable
reductions
PD
gains
CAL
observed,
some
showing
statistically
significant
benefits.
However,
heterogeneity
concentrations
(0.2–1.4%),
application
methods,
treatment
frequencies,
follow-up
durations
(1
week
12
months)
limits
definitive
conclusions.
Additionally,
did
not
significantly
affect
reduction
P.
gingivalis
prevalence.
Conclusions:
conjunction
shows
promise
therapy.
methodologies
indicates
necessity
high-quality,
standardized
randomized
controlled
trials
establish
clear
guidelines
periodontitis.
Язык: Английский
Integrating e-cigarette (vaping) questions into medical and dental charts: a critical need
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology,
Год журнала:
2023,
Номер
137(2), С. 93 - 94
Опубликована: Окт. 29, 2023
The
use
of
nicotine-containing
products
has
changed
significantly
as
electronic
cigarettes
(e-cigarettes)
and
vaporizers
have
become
devices
with
huge
commercial
potential.1The
Tobacco
Atlas.
Challenges
e-cigarettes
&
HTP.
Accessed
March
27,
2023.
https://tobaccoatlas.org/challenges/e-cigarettes-htps/Google
Scholar,2Martins
BNFL
Normando
AGC
Rodrigues-Fernandes
CI
et
al.Global
frequency
epidemiological
profile
cigarette
users:
a
systematic
review.Oral
Surg,
Oral
Med,
Pathol
Radiol.
2022;
134:
548-561Abstract
Full
Text
PDF
PubMed
Scopus
(5)
Google
Scholar
initial
aim
these
was
to
help
smokers
reduce
their
tobacco
consumption
quit
the
habit;
however,
evidence
shown
that
rapidly
popular
around
world,
predominantly
among
young
people
who
never
been
smokers.3Tobacco
Use:
Considerations
for
Clinicians.
American
Academy
Pediatrics.
Oct
5,
https://www.aap.org/en/patient-care/tobacco-control-and-prevention/youth-tobacco-cessation/tobacco-use-considerations-for-clinicians/Google
Scholar,4Lee
R.
Rethinking
e-smoking.Br
Dent
J.
2023;
234:
12Crossref
(2)
E-cigarettes
are
store
release
nicotine
by
aerosolized
vapor
containing
myriad
other
harmful
potentially
carcinogenic
substances
poorly
understood
in
terms
product
formulation
linked
range
health
issues,
including
respiratory,5Jonas
A
Impact
vaping
on
respiratory
health.BMJ.
378e065997Google
cardiovascular,6Rose
JJ
Krishnan-Sarin
S
Exil
VJ
al.Cardiopulmonary
impact
products:
Scientific
Statement
From
Heart
Association.Circulation.
148:
703-728Crossref
(13)
oral
conditions.7Niemczyk
Niemczyk
W
Prokurat
M
al.Impact
-
literature
review.Pol
Merkur
Lekarski.
51:
271-275Crossref
(1)
Traditionally,
providers
routinely
inquired
about
patients'
alcohol
part
comprehensive
medical
history
assessment.
These
questions
proven
central
assessing
overall
risks
guiding
treatment
plans.
However,
increase
e-cigarette
usage,
need
adapt
our
approach
collect
more
data
clear.4Lee
Therefore,
it
is
crucial
care
professionals
detailed
information
use,
alongside
traditional
inquiries
regarding
smoking
drinking
habits,
better
understand
its
short-
long-term
implications
health.
incorporation
related
dental
records
should
cover
various
aspects,
those
suggested
below.1.Type:
neither
widely
regulated
nor
well
standardized
commercially;
therefore,
patients
be
asked
specific
type
they
considering
there
than
400
different
brands8Zhu
SH
Sun
JY
Bonnevie
E
al.Four
hundred
sixty
brands
counting:
regulation.Tob
Control.
2014;
23:
iii3-iii9Crossref
(733)
approximately
20,000
e-liquids.9Havermans
Krüsemann
EJZ
Pennings
J
de
Graaf
K
Boesveldt
Talhout
Nearly
20
000
e-liquids
250
unique
flavour
descriptions:
an
overview
Dutch
market
based
from
manufacturers.Tob
2021;
30:
57-62Crossref
(46)
This
improves
understanding
content
device,
amount
inhaled,
how
many
"puffs"
user
can
take
per
device
(each
mL
liquid
allows
300
"puffs").2.Duration
use:
Knowing
long
patient
using
us
any
cumulative
effects
associated
devices,
intensity
exposure
risk
addiction.
In
this
context,
advisable
ask
average
duration
each
until
buy
new
one
or
recharge
current
one.4Lee
Scholar3.Time
Asking
when
usually
identify
patterns
associative
stress,
professional,
social
situations,
cravings,
which
guide
interventions
aimed
at
cessation.4.Simultaneous
Assessing
whether
conjunction
products,
cannabis,
recreational
illicit
drugs
obtain
view
potential
aggravating
identifying
approaches.5.General
symptoms:
Encouraging
report
adverse
symptoms
associate
detect
treat
early
signs
e-cigarette-related
problems.6.Oral
Dental
attribute
such
dry
mouth,
gum
irritation,
unusual
taste
sensations,
sore
throat.
indicate
possible
problems
manifestations.
We
propose
integrating
aforementioned
questions,
aspects
will
evident
coming
years
large
international
dimension
reached
short
time,2Martins
into
allow
determine
habits
systemic
personalized
plans,
facilitate
intervention,
educate
consequences
use.
To
goal,
imperative
ensure
both
undergraduate
students
receive
education
vaping.10Martín
Carreras-Presas
C
Naeim
Hsiou
D
Somacarrera
Pérez
ML
Messadi
DV
future
E-cigarette
effects.Eur
Educ.
2018;
22:
e751-e758Crossref
(11)
conclusion,
continues
seems
meeting
little
resistance
creation
implementation
public
policies
regulate
control
inevitable
physicians
dentists
collection
methods
encompass
contemporary
pattern
consumption.
sense,
fundamental
step
toward
clinical
care.
It's
time
recognize
importance
defend
well-being
through
objective
formally
recorded
and,
useful
informed
policies.
None.
Язык: Английский