Long COVID and gut microbiome: insights into pathogenesis and therapeutics DOI Creative Commons
Raphaela Iris Lau, Qi Su, Siew C. Ng

и другие.

Gut Microbes, Год журнала: 2025, Номер 17(1)

Опубликована: Янв. 24, 2025

Post-acute coronavirus disease 2019 syndrome (PACS), following severe acute respiratory 2 (SARS-CoV-2) infection or (COVID-19), is typically characterized by long-term debilitating symptoms affecting multiple organs and systems. Unfortunately, there currently a lack of effective treatment strategies. Altered gut microbiome has been proposed as one the plausible mechanisms involved in pathogenesis PACS; extensive studies have emerged to bridge gap between persistent dysbiosis microbiome. Recent clinical trials indicated that modulation using probiotics, prebiotics, fecal microbiota transplantation (FMT) led improvements related PACS, including fatigue, memory loss, difficulty concentration, gastrointestinal upset, disturbances sleep mood. In this review, we highlight latest evidence on key microbial alterations observed well use microbiome-based therapeutics managing PACS symptoms. These novel findings altogether shed light other chronic conditions.

Язык: Английский

Navigating the (Post-) Pandemic Landscape: An Analysis of COVID-19’s Current Status and Future Implications DOI

Filippo Bistagnino,

Arunkumar Subramanian, Marcos Roberto Tovani‐Palone

и другие.

Disaster Medicine and Public Health Preparedness, Год журнала: 2025, Номер 19

Опубликована: Янв. 1, 2025

Abstract Although it is true that the coronavirus disease 2019 (COVID-19) situation has improved significantly around world, especially after implementation of mass vaccination campaigns, there still a lack consensus both in literature and among health authorities other stakeholders about current epidemiological situation. This, turn, been intensified World Health Organization declared end public emergency international concern related to COVID-19. In this context, worrying questions have arisen, including rampant dissemination scientific misinformation coupled with increased resistance and/or revocation appropriate measures. response these challenges hoping contribute their mitigation, article addresses aspects COVID-19, discusses long COVID its controversies, intensification as well considerations on surveillance, recommendations for improving existing

Язык: Английский

Процитировано

1
Long COVID and gut microbiome: insights into pathogenesis and therapeutics DOI Creative Commons
Raphaela Iris Lau, Qi Su, Siew C. Ng

и другие.

Gut Microbes, Год журнала: 2025, Номер 17(1)

Опубликована: Янв. 24, 2025

Post-acute coronavirus disease 2019 syndrome (PACS), following severe acute respiratory 2 (SARS-CoV-2) infection or (COVID-19), is typically characterized by long-term debilitating symptoms affecting multiple organs and systems. Unfortunately, there currently a lack of effective treatment strategies. Altered gut microbiome has been proposed as one the plausible mechanisms involved in pathogenesis PACS; extensive studies have emerged to bridge gap between persistent dysbiosis microbiome. Recent clinical trials indicated that modulation using probiotics, prebiotics, fecal microbiota transplantation (FMT) led improvements related PACS, including fatigue, memory loss, difficulty concentration, gastrointestinal upset, disturbances sleep mood. In this review, we highlight latest evidence on key microbial alterations observed well use microbiome-based therapeutics managing PACS symptoms. These novel findings altogether shed light other chronic conditions.

Язык: Английский

Процитировано

0