Liquid biopsy and its significance in tumour – Detection in the field of pathology
Journal of Oral and Maxillofacial Pathology,
Год журнала:
2023,
Номер
27(1), С. 195 - 200
Опубликована: Янв. 1, 2023
The
treatment
of
cancer
has
remarkably
improved
because
increased
knowledge
the
abnormalities
at
molecular
level,
which
results
in
human
growth.
This
initiated
development
ever
more
successful
as
well
effective
targeted
therapies.
Detection
is
diagnosed
basically
by
performing
routine
biopsy/cytology,
many
drawbacks.
Therefore,
concept
liquid
biopsy
been
introduced
to
oncology,
potential
revolutionise
management
patients,
eliminating
invasive
procedures
needed
obtain
tissue
samples
and
provide
information.
Liquid
analysis
tumour
cells
or
cell
products
obtained
from
blood
other
body
fluids,
providing
a
broad
range
opportunities
field
pathology.
Here,
we
focus
on
most
prominent
markers,
circulating
tumour-derived
deoxyribonucleic
acid
(DNA),
patients.
In
this
review,
discuss
recent
clinical
studies
these
biomarkers
for
early
detection
prognostication
cancer,
helps
management.
Hence,
with
great
promise
personalised
medicine
its
ability
multiple
non-invasive
snapshots
primary
metastatic
tumours.
Язык: Английский
Longitudinal interpretability of deep learning based breast cancer risk prediction
Physics in Medicine and Biology,
Год журнала:
2024,
Номер
70(1), С. 015001 - 015001
Опубликована: Дек. 11, 2024
Deep-learning-based
models
have
achieved
state-of-the-art
breast
cancer
risk
(BCR)
prediction
performance.
However,
these
are
highly
complex,
and
the
underlying
mechanisms
of
BCR
not
fully
understood.
Key
questions
include
whether
can
detect
morphologic
changes
that
lead
to
cancer.
These
findings
would
boost
confidence
in
utilizing
practice
provide
clinicians
with
new
perspectives.
In
this
work,
we
aimed
determine
when
oncogenic
processes
sufficient
signal
for
changes.
Язык: Английский